PAAF1 antibody (N-Term)
PAAF1
Reactivity: Human
WB, IHC (p)
Host: Rabbit
Polyclonal
RB25789
unconjugated
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- Target See all PAAF1 Antibodies
- PAAF1 (Proteasomal ATPase-Associated Factor 1 (PAAF1))
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Binding Specificity
- AA 109-138, N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PAAF1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Predicted Reactivity
- B
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This PAAF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-138 amino acids from the N-terminal region of human PAAF1.
- Clone
- RB25789
- Isotype
- Ig Fraction
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anti-Proteasomal ATPase-Associated Factor 1 (PAAF1) (AA 57-106) antibody
PAAF1 Reactivity: Human, Dog, Guinea Pig, Horse, Rabbit, Bat, Pig WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB: 1:1000. IHC-P: 1:50~100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Expiry Date
- 6 months
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- Target
- PAAF1 (Proteasomal ATPase-Associated Factor 1 (PAAF1))
- Alternative Name
- PAAF1 (PAAF1 Products)
- Synonyms
- paaf antibody, rpn14 antibody, wdr71 antibody, WDR71 antibody, MGC146521 antibody, PAAF antibody, Rpn14 antibody, proteasomal ATPase associated factor 1 S homeolog antibody, proteasomal ATPase associated factor 1 antibody, paaf1.S antibody, PAAF1 antibody, paaf1 antibody, Paaf1 antibody
- Background
- PAAF1 inhibits proteasome 26S assembly and proteolytic activity by impairing the association of the 19S regulatory complex with the 20S core. In case of HIV-1 infection, recruited by viral Tat to the HIV-1 promoter, where it promotes the recruitment of 19S regulatory complex through dissociation of the proteasome 26S. This presumably promotes provirus transcription efficiency.
- Molecular Weight
- 42190
- Gene ID
- 80227
- NCBI Accession
- NP_001254732, NP_001254733, NP_001254734, NP_001254735, NP_079431
- UniProt
- Q9BRP4
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