SETD7 antibody (AA 107-366)
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- Target See all SETD7 Antibodies
- SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))
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Binding Specificity
- AA 107-366
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Reactivity
- Human, Rat, Monkey
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This SETD7 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)
- Purification
- purified
- Immunogen
- Purified recombinant fragment of human SETD7 (AA: 107-366) expressed in E. coli.
- Clone
- 1B3B8
- Isotype
- IgG2a
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anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (AA 107-366) antibody
SETD7 Reactivity: Human, Rat, Monkey WB, ELISA, IHC, FACS, ICC, Neut Host: Mouse Monoclonal 3D6G11 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (AA 257-366) antibodySETD7 Reactivity: Human WB, ELISA, IHC (p), IF Host: Mouse Monoclonal 5B4 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (AA 159-189) antibodySETD7 Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB2763 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (AA 257-366) antibodySETD7 Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) antibodySETD7 Reactivity: Human WB, ELISA, IHC, IHC (p) Host: Mouse Monoclonal S4E5 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) antibodySETD7 Reactivity: Human, Mouse WB, FACS Host: Mouse Monoclonal 2E3 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (AA 1-366) antibodySETD7 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (AA 1-218) antibodySETD7 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (AA 1-366) antibodySETD7 Reactivity: Human WB, ELISA, FACS, IF, ICC Host: Mouse Monoclonal s4E5 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (C-Term) antibodySETD7 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400, ICC: N/A, IHC: N/A
- Restrictions
- For Research Use only
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- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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- Target
- SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))
- Alternative Name
- SETD7 (SETD7 Products)
- Synonyms
- KMT7 antibody, SET7 antibody, SET7/9 antibody, SET9 antibody, set7 antibody, zgc:101860 antibody, zgc:92330 antibody, 1600028F23Rik antibody, H3K4MT antibody, Set7 antibody, Set7/9 antibody, mKIAA1717 antibody, SET domain containing lysine methyltransferase 7 antibody, SET domain containing (lysine methyltransferase) 7 antibody, SETD7 antibody, setd7 antibody, Setd7 antibody
- Background
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Description: Histone methyltransferase that specifically monomethylates Lys-4 of histone H3. H3 Lys-4 methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates Lys-189 of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates Lys-372 of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation.
Aliases: KMT7, SET7, SET9, SET7/9
- Molecular Weight
- 40.7 kDa
- Gene ID
- 80854
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