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SLC7A5 antibody (AA 101-200)

SLC7A5 Reactivity: Human, Mouse, Rat, Pig WB, ELISA, IHC (p), IF (cc) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1387470
  • Target See all SLC7A5 Antibodies
    SLC7A5 (Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 (SLC7A5))
    Binding Specificity
    • 14
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-200
    Reactivity
    • 31
    • 16
    • 15
    • 14
    • 3
    • 3
    • 2
    • 2
    • 2
    Human, Mouse, Rat, Pig
    Host
    • 29
    • 2
    • 1
    Rabbit
    Clonality
    • 29
    • 3
    Polyclonal
    Conjugate
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SLC7A5 antibody is un-conjugated
    Application
    • 23
    • 12
    • 7
    • 6
    • 5
    • 5
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Cross-Reactivity
    Human, Mouse, Pig, Rat
    Predicted Reactivity
    Dog,Cow,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human SLC7A5
    Isotype
    IgG
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Beals, Sukiennik, Nallabelli, Emmons, van Vliet, Young, Ulanov, Li, Paluska, De Lisio, Burd: "Anabolic sensitivity of postprandial muscle protein synthesis to the ingestion of a protein-dense food is reduced in overweight and obese young adults." in: The American journal of clinical nutrition, Vol. 104, Issue 4, pp. 1014-1022, (2016) (PubMed).

    Mayers, Torrence, Danai, Papagiannakopoulos, Davidson, Bauer, Lau, Ji, Dixit, Hosios, Muir, Chin, Freinkman, Jacks, Wolpin, Vitkup, Vander Heiden: "Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers." in: Science (New York, N.Y.), Vol. 353, Issue 6304, pp. 1161-5, (2016) (PubMed).

  • Target
    SLC7A5 (Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 (SLC7A5))
    Alternative Name
    SLC7A5 (SLC7A5 Products)
    Synonyms
    4F2LC antibody, CD98 antibody, D16S469E antibody, E16 antibody, LAT1 antibody, MPE16 antibody, hLAT1 antibody, D0H16S474E antibody, TA1 antibody, JHI-21 antibody, SLC7A5 antibody, LAT-1 antibody, slc7a5a antibody, 4F2 antibody, 4F2HC antibody, AI314110 antibody, Cd98 antibody, Ly-10 antibody, Ly-m10 antibody, Ly10 antibody, Mdu1 antibody, Mgp-2hc antibody, NACAE antibody, solute carrier family 7 member 5 antibody, solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 antibody, solute carrier family 7 (amino acid transporter light chain, L system), member 5 antibody, solute carrier family 7 member 5 S homeolog antibody, solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 antibody, SLC7A5 antibody, Slc7a5 antibody, slc7a5.S antibody, Slc3a2 antibody
    Background

    Synonyms: Large neutral amino acids transporter small subunit 1, 4F2 light chain, 4F2 LC, 4F2LC, CD98 light chain, Integral membrane protein E16, L-type amino acid transporter 1, hLAT1, Solute carrier family 7 member 5, y+ system cationic amino acid transporter, SLC7A5, CD98LC, LAT1, MPE16

    Background: Sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Involved in cellular amino acid uptake. Acts as an amino acid exchanger. Involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Plays a role in neuronal cell proliferation (neurogenesis) in brain. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. May play an important role in high-grade gliomas. Mediates blood-to-retina L-leucine transport across the inner blood-retinal barrier which in turn may play a key role in maintaining large neutral amino acids as well as neurotransmitters in the neural retina. Acts as the major transporter of tyrosine in fibroblasts.

    Gene ID
    8140
    UniProt
    Q01650
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