Midkine antibody (Internal Region)
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- Target See all Midkine (MDK) Antibodies
- Midkine (MDK) (Midkine (Neurite Growth-Promoting Factor 2) (MDK))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Midkine antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Specificity
- MDK Antibody detects endogenous levels of total MDK.
- Predicted Reactivity
- Pig,Bovine,Sheep,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human MDK, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product MDK Primary Antibody
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anti-Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 22-140) antibody
MDK Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 21-143) antibodyMDK Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 22-143) antibodyMDK Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 113-143), (C-Term) antibodyMDK Reactivity: Human WB, IF, IHC (p) Host: Rabbit Polyclonal RB14452 unconjugated
anti-Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 110-143), (C-Term) antibodyMDK Reactivity: Human, Mouse WB, IF, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
anti-Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 21-143) antibodyMDK Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Midkine (Neurite Growth-Promoting Factor 2) (MDK) antibodyMDK Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 1-143) antibodyMDK Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 22-140) antibodyMDK Reactivity: Rat WB, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 113-143), (C-Term) antibodyMDK Reactivity: Human, Mouse WB, IF, IHC (p) Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- Midkine (MDK) (Midkine (Neurite Growth-Promoting Factor 2) (MDK))
- Alternative Name
- MDK (MDK Products)
- Synonyms
- ARAP antibody, MK antibody, NEGF2 antibody, Mek antibody, MK-B antibody, PTF-alpha-1 antibody, mdk antibody, midkine antibody, negf2 antibody, RIHB antibody, cb518 antibody, fb79b05 antibody, fj33b02 antibody, fj48a12 antibody, mdk2 antibody, plei2 antibody, wu:fb79b05 antibody, wu:fj33b02 antibody, wu:fj48a12 antibody, MK-A antibody, PTF-alpha-2 antibody, X-PTF-alpha1 antibody, XMK antibody, mdk-a antibody, mdk-b antibody, midkine antibody, midkine L homeolog antibody, midkine (neurite growth-promoting factor 2) antibody, midkine b antibody, midkine S homeolog antibody, MDK antibody, Mdk antibody, mdk.L antibody, mdkb antibody, mdk.S antibody
- Background
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Description: Developmentally regulated, secreted growth factor homologous to pleiotrophin (PTN), which has heparin binding activity. Binds anaplastic lymphoma kinase (ALK) which induces ALK activation and subsequent phosphorylation of the insulin receptor substrate (IRS1), followed by the activation of mitogen-activated protein kinase (MAPK) and PI3-kinase, and the induction of cell proliferation. Involved in neointima formation after arterial injury, possibly by mediating leukocyte recruitment. Also involved in early fetal adrenal gland development (By similarity).
Gene: MDK
- Molecular Weight
- 16kDa
- Gene ID
- 4192
- UniProt
- P21741
- Pathways
- RTK Signaling, M Phase, Skeletal Muscle Fiber Development
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