UNC93B1 antibody (AA 451-550)
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- Target See all UNC93B1 Antibodies
- UNC93B1 (Unc-93 Homolog B1 (UNC93B1))
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Binding Specificity
- AA 451-550
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This UNC93B1 antibody is un-conjugated
- Application
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Predicted Reactivity
- Human,Mouse,Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human UNC93B
- Isotype
- IgG
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anti-Unc-93 Homolog B1 (UNC93B1) (AA 83-135) antibody
UNC93B1 Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
anti-Unc-93 Homolog B1 (UNC93B1) (AA 500-550) antibodyUNC93B1 Reactivity: Human, Mouse, Rat, Dog, Cow WB Host: Rabbit Polyclonal unconjugated
anti-Unc-93 Homolog B1 (UNC93B1) (AA 61-110) antibodyUNC93B1 Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio), Monkey WB Host: Rabbit Polyclonal unconjugated
anti-Unc-93 Homolog B1 (UNC93B1) (AA 450-550) antibodyUNC93B1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Unc-93 Homolog B1 (UNC93B1) (N-Term) antibodyUNC93B1 Reactivity: Human, Mouse, Rat WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
anti-Unc-93 Homolog B1 (UNC93B1) (AA 300-597) antibodyUNC93B1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Unc-93 Homolog B1 (UNC93B1) (N-Term) antibodyUNC93B1 Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- UNC93B1 (Unc-93 Homolog B1 (UNC93B1))
- Alternative Name
- UNC93B (UNC93B1 Products)
- Synonyms
- UNC93 antibody, IIAE1 antibody, UNC93B antibody, Unc-93B1 antibody, Unc93b antibody, unc-93 homolog B1, TLR signaling regulator antibody, unc-93 homolog B1 (C. elegans) antibody, UNC93B1 antibody, Unc93b1 antibody
- Background
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Synonyms: IIAE1, UNC93, UNC93B, Unc-93B1, Protein unc-93 homolog B1, hUNC93B1, UNC93B1
Background: Plays an important role in innate and adaptive immunity by regulating nucleotide-sensing Toll-like receptor (TLR) signaling. Required for the transport of a subset of TLRs (including TLR3, TLR7 and TLR9) from the endoplasmic reticulum to endolysosomes where they can engage pathogen nucleotides and activate signaling cascades. May play a role in autoreactive B-cells removal.
- Gene ID
- 81622
- UniProt
- Q9H1C4
- Pathways
- TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
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