QTRT1 antibody (Catalytic Subunit 1)
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- Target See all QTRT1 Antibodies
- QTRT1 (Queuine tRNA-Ribosyltransferase 1 (QTRT1))
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Binding Specificity
- AA 211-403, Catalytic Subunit 1
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This QTRT1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Queuine tRNA-ribosyltransferase catalytic subunit 1 protein (211-403AA)
- Isotype
- IgG
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anti-Queuine tRNA-Ribosyltransferase 1 (QTRT1) (AA 1-358) antibody
QTRT1 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-Queuine tRNA-Ribosyltransferase 1 (QTRT1) (AA 345-371), (C-Term) antibodyQTRT1 Reactivity: Human WB Host: Rabbit Polyclonal RB37610 unconjugated
anti-Queuine tRNA-Ribosyltransferase 1 (QTRT1) antibodyQTRT1 Reactivity: Human, Mouse, Rat WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Queuine tRNA-Ribosyltransferase 1 (QTRT1) (AA 45-94) antibodyQTRT1 Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Zebrafish (Danio rerio), Rabbit, Bat, Monkey, Drosophila melanogaster WB Host: Rabbit Polyclonal unconjugated
anti-Queuine tRNA-Ribosyltransferase 1 (QTRT1) (AA 252-301) antibodyQTRT1 Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Zebrafish (Danio rerio), Guinea Pig, Bat, Monkey, Pig, Xenopus laevis WB Host: Rabbit Polyclonal unconjugated
anti-Queuine tRNA-Ribosyltransferase 1 (QTRT1) (AA 22-340) antibodyQTRT1 Reactivity: Human, Mouse WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- QTRT1 (Queuine tRNA-Ribosyltransferase 1 (QTRT1))
- Alternative Name
- QTRT1 (QTRT1 Products)
- Synonyms
- CG4947 antibody, Dmel\\CG4947 antibody, TGT antibody, tgt antibody, zgc:66378 antibody, FP3235 antibody, TGUT antibody, 2610028E17Rik antibody, Tgt antibody, Tgut antibody, tRNA-guanine transglycosylase antibody, queuine tRNA-ribosyltransferase 1 S homeolog antibody, queuine tRNA-ribosyltransferase 1 antibody, queuine tRNA-ribosyltransferase catalytic subunit 1 antibody, Tgt antibody, Olsu_0732 antibody, Palpr_1298 antibody, Riean_1227 antibody, Calni_1240 antibody, Ftrac_0312 antibody, Ocepr_1541 antibody, Sulku_0977 antibody, Tmar_0854 antibody, Bache_2323 antibody, Nitsa_1291 antibody, Isop_1657 antibody, Despr_0021 antibody, Pedsa_1842 antibody, Corgl_1148 antibody, Mahau_0921 antibody, Theth_0831 antibody, qtrt1.S antibody, qtrt1 antibody, QTRT1 antibody, Qtrt1 antibody
- Background
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Background: Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GUN anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (PubMed:11255023, PubMed:20354154). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1\\\' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming queuine, allowing a nucleophilic attack on the C1\\\' of the ribose to form the product (By similarity).
Aliases: FP3235 antibody, Guanine insertion enzyme antibody, qtrt1 antibody, Queuine tRNA ribosyltransferase 1 antibody, Queuine tRNA ribosyltransferase antibody, Queuine tRNA-ribosyltransferase antibody, TGT antibody, TGT, 43 KD subunit antibody, TGT, catalytic subunit antibody, TGT_HUMAN antibody, TGUT antibody, tRNA guanine transglycosylase antibody, tRNA-guanine transglycosylase antibody
- UniProt
- Q9BXR0
- Pathways
- Ribonucleoside Biosynthetic Process
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