FZD8 antibody (AA 55-233)
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- Target See all FZD8 Antibodies
- FZD8 (Frizzled Family Receptor 8 (FZD8))
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Binding Specificity
- AA 55-233
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FZD8 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Cross-Reactivity
- Human, Mouse
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Frizzled-8 protein (55-233AA)
- Isotype
- IgG
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anti-Frizzled Family Receptor 8 (FZD8) (N-Term) antibody
FZD8 Reactivity: Human, Mouse, Rat WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Frizzled Family Receptor 8 (FZD8) antibodyFZD8 Reactivity: Human, Mouse, Rat ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Frizzled Family Receptor 8 (FZD8) (C-Term) antibodyVerified FZD8 Reactivity: Human WB, ELISA, IHC, IF, IEM Host: Goat Polyclonal unconjugated
anti-Frizzled Family Receptor 8 (FZD8) (AA 72-161) antibodyFZD8 Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
anti-Frizzled Family Receptor 8 (FZD8) (Extracellular Domain) antibodyFZD8 Reactivity: Human, Mouse, Rat, Cow, Dog, Monkey, Rabbit IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Frizzled Family Receptor 8 (FZD8) (N-Term) antibodyFZD8 Reactivity: Human, Mouse, Rat, Cow, Monkey, Xenopus laevis, Horse IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Frizzled Family Receptor 8 (FZD8) (C-Term) antibodyFZD8 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Frizzled Family Receptor 8 (FZD8) (C-Term) antibodyFZD8 Reactivity: Human WB, IHC, IF, IC Host: Rabbit Polyclonal unconjugated
anti-Frizzled Family Receptor 8 (FZD8) (N-Term) antibodyFZD8 Reactivity: Human, Mouse, Rat, Dog WB Host: Rabbit Polyclonal unconjugated
anti-Frizzled Family Receptor 8 (FZD8) (AA 144-193) antibodyFZD8 Reactivity: Human, Monkey WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- FZD8 (Frizzled Family Receptor 8 (FZD8))
- Alternative Name
- FZD8 (FZD8 Products)
- Synonyms
- FZ-8 antibody, hFZ8 antibody, FZD8 antibody, Fz-8 antibody, frizzled8 antibody, xfz8 antibody, Xfz8 antibody, frizzled-8 antibody, hfz8 antibody, Fz8 antibody, fzd8 antibody, fz5 antibody, fz8a antibody, fzc antibody, wu:fd02c05 antibody, zg05 antibody, ZG06 antibody, Zfz8b antibody, fz6 antibody, fz8b antibody, fzA antibody, ik:tdsubc_1e1 antibody, xx:tdsubc_1e1 antibody, zfzA antibody, frizzled class receptor 8 antibody, frizzled class receptor 8 S homeolog antibody, frizzled class receptor 8 L homeolog antibody, frizzled class receptor 8a antibody, frizzled class receptor 8b antibody, FZD8 antibody, fzd8.S antibody, fzd8 antibody, Fzd8 antibody, fzd8.L antibody, fzd8a antibody, fzd8b antibody
- Background
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Background: Receptor for Wnt proteins. Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalosomes. The beta-catenin canonical signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Coreceptor along with RYK of Wnt proteins, such as WNT1.
Aliases: Frizzled 8 seven transmembrane spanning receptor antibody, frizzled 8, seven transmembrane spanning receptor antibody, Frizzled family receptor 8 antibody, frizzled homolog 8 (Drosophila) antibody, Frizzled homolog 8 antibody, Frizzled-8 antibody, FZ 8 antibody, Fz-8 antibody, FZ8 antibody, FZD 8 antibody, FZD8 antibody, FZD8_HUMAN antibody, hFZ 8 antibody, hFz8 antibody, HGNC4046 antibody, Homolog of Drosophila Frizzled 8 antibody
- UniProt
- Q9H461
- Pathways
- WNT Signaling
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