APH1B antibody (AA 93-110)
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- Target See all APH1B (Aph1b) Antibodies
- APH1B (Aph1b) (Anterior Pharynx Defective 1 Homolog B (Aph1b))
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Binding Specificity
- AA 93-110
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This APH1B antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Peptide sequence from Human Gamma-secretase subunit APH-1B protein (93-110AA)
- Isotype
- IgG
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anti-Anterior Pharynx Defective 1 Homolog B (Aph1b) (AA 51-150) antibody
Aph1b Reactivity: Mouse WB, ELISA, IF (p), IF (cc), IHC (fro), IHC (p), ICC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Recommended dilution: WB:1:1000-1:5000,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- APH1B (Aph1b) (Anterior Pharynx Defective 1 Homolog B (Aph1b))
- Alternative Name
- APH1B (Aph1b Products)
- Synonyms
- APH-1B antibody, PRO1328 antibody, PSFL antibody, TAAV688 antibody, APH-1B' antibody, 2310057K14Rik antibody, Aph1c antibody, aph-1 homolog B, gamma-secretase subunit antibody, aph-1 homolog B, gamma secretase subunit antibody, aph1 homolog B, gamma secretase subunit antibody, APH1B antibody, Aph1b antibody
- Background
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Background: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex. Probably present in a minority of gamma-secretase complexes compared to APH1A.
Aliases: Anterior pharynx defective 1 homolog B (C. elegans) antibody, Anterior pharynx defective 1 homolog B antibody, Anterior pharynx defective 1B like antibody, Anterior pharynx defective 1b short splicing variant antibody, APH 1B antibody, Aph 1beta antibody, APH-1b antibody, Aph-1beta antibody, Aph1 beta antibody, aph1b antibody, APH1B_HUMAN antibody, Aph1beta antibody, DKFZp564D0372 antibody, Gamma secretase subunit APH 1B antibody, Gamma secretase subunit APH1B antibody, Gamma secretase sununit antibody, Gamma-secretase subunit Aph-1b antibody, Presenilin stabilisation factor like antibody, Presenilin-stabilization factor-like antibody, PRO 1328 antibody, PRO1328 antibody, PSFL antibody, TAAV 688 antibody, TAAV688 antibody
- UniProt
- Q8WW43
- Pathways
- Notch Signaling, Neurotrophin Signaling Pathway
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