VDAC1 antibody (Middle Region)
(1 reference)-
- Target See all VDAC1 Antibodies
- VDAC1 (Voltage-Dependent Anion Channel 1 (VDAC1))
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Binding Specificity
- AA 154-181, Middle Region
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This VDAC1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purpose
- Rabbit IgG polyclonal antibody for Voltage-dependent anion-selective channel protein 1(VDAC1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- Sequence
- QMNFETAKSR VTQSNFAVGY KTDEFQLH
- Cross-Reactivity (Details)
- No cross reactivity with other proteins.
- Characteristics
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Rabbit IgG polyclonal antibody for Voltage-dependent anion-selective channel protein 1(VDAC1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: voltage-dependent anion channel 1
Protein Name: Voltage-dependent anion-selective channel protein 1 - Purification
- Immunogen affinity purified.
- Immunogen
- A synthetic peptide corresponding to a sequence in the middle region of human VDAC/Porin (154-181aa QMNFETAKSRVTQSNFAVGYKTDEFQLH), different from the related mouse and rat sequences by one amino acid.
- Isotype
- IgG
- Top Product
- Discover our top product VDAC1 Primary Antibody
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anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 1-30), (N-Term) antibody
VDAC1 Reactivity: Human, Mouse WB, IHC (p), FACS Host: Rabbit Polyclonal RB19920 unconjugated
anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 1-283) antibodyVDAC1 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 95-124) antibodyVDAC1 Reactivity: Human WB, IHC (p), FACS Host: Rabbit Polyclonal RB19925 unconjugated
anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 1-283) antibodyVDAC1 Reactivity: Human WB, IHC, ICC, IF Host: Mouse Monoclonal S152B-23 unconjugated
anti-Voltage-Dependent Anion Channel 1 (VDAC1) (N-Term) antibodyVDAC1 Reactivity: Human WB, IHC, ICC, IF Host: Rabbit Polyclonal unconjugated
anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 1-283) antibody (HRP)VDAC1 Reactivity: Human WB, IHC, ICC, IF Host: Mouse Monoclonal S152B-23 HRP
anti-Voltage-Dependent Anion Channel 1 (VDAC1) (N-Term) antibody (HRP)VDAC1 Reactivity: Human WB, IHC, ICC, IF Host: Rabbit Polyclonal HRP
anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 1-283) antibody (FITC)VDAC1 Reactivity: Human WB, IHC, ICC, IF Host: Mouse Monoclonal S152B-23 FITC
anti-Voltage-Dependent Anion Channel 1 (VDAC1) (N-Term) antibody (FITC)VDAC1 Reactivity: Human WB, IHC, ICC, IF Host: Rabbit Polyclonal FITC
anti-Voltage-Dependent Anion Channel 1 (VDAC1) (AA 1-283) antibody (Alkaline Phosphatase (AP))VDAC1 Reactivity: Human WB, IHC, ICC, IF Host: Mouse Monoclonal S152B-23 Alkaline Phosphatase (AP)
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- Application Notes
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for VDAC/Porin is approximately 0.1 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - Comment
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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: "MicroRNA-27b Regulates Mitochondria Biogenesis in Myocytes." in: PLoS ONE, Vol. 11, Issue 2, pp. e0148532, (2016) (PubMed).
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: "MicroRNA-27b Regulates Mitochondria Biogenesis in Myocytes." in: PLoS ONE, Vol. 11, Issue 2, pp. e0148532, (2016) (PubMed).
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- Target
- VDAC1 (Voltage-Dependent Anion Channel 1 (VDAC1))
- Alternative Name
- VDAC1 (VDAC1 Products)
- Synonyms
- vdac1 antibody, VDAC1 antibody, 5076 antibody, ARABIDOPSIS THALIANA VOLTAGE DEPENDENT ANION CHANNEL 1 antibody, ATVDAC1 antibody, T22N4.9 antibody, T22N4_9 antibody, voltage dependent anion channel 1 antibody, PORIN antibody, VDAC-1 antibody, AL033343 antibody, Vdac5 antibody, fa13f11 antibody, wu:fa13f11 antibody, zgc:85830 antibody, voltage-dependent anion channel 1 S homeolog antibody, voltage-dependent anion channel 1 antibody, voltage dependent anion channel 1 antibody, vdac1.S antibody, vdac1 antibody, VDAC1 antibody, Vdac1 antibody
- Background
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The voltage-dependent anion channel (VDAC) of the outer mitochondrial membrane is a small, abundant outer membrane pore-forming protein found in the outer membranes of all eukaryotic mitochondria. The VDAC protein is thought to form the major pathway for movement of adenine nucleotides through the outer membrane and to be the mitochondrial binding site for hexokinase and glycerol kinase. At low transmembrane voltage, VDAC is open for anions such as phosphate, chloride, and adenine nucleotides. At higher transmembrane voltage, VDAC functions as a selective channel for cations and uncharged molecules. These features make VDAC likely to play a role in mitochondrial energy metabolism. Huizing et al. studied by Northern and Western blot analyses the human tissue distribution of mitochondrial transmembrane metabolite carriers. They found that VDAC1 mRNA has a ubiquitous distribution, with most pronounced expression in heart, liver, and skeletal muscle, whereas the VDAC2 isoform appears to be expressed only in the heart.
Synonyms: N2441 antibody|OMP2 antibody|POR1 antibody|hVDAC1 antibody|MGC111064 antibody|Mitochondrial Porin antibody|Outer mitochondrial membrane protein porin 1 antibody|Plasmalemmal porin antibody|Porin 31 HL antibody|Porin 31HL antibody|Porin 31HM antibody|VDAC 1 antibody|VDAC antibody|VDAC-1 antibody|VDAC1 antibody|VDAC1_HUMAN antibody|Voltage dependent anion channel 1 antibody|Voltage dependent anion selective channel protein 1 antibody|Voltage-dependent anion-selective channel protein 1 antibody|YNL055C antibody|YNL2441C antibody - Gene ID
- 7416
- UniProt
- P21796
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