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AKR1C1 antibody

DDH Reactivity: Human, Mouse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7256524
  • Target See all AKR1C1 (DDH) Antibodies
    AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))
    Reactivity
    • 34
    • 12
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 28
    • 6
    Rabbit
    Clonality
    • 31
    • 3
    Polyclonal
    Conjugate
    • 23
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AKR1C1 antibody is un-conjugated
    Application
    • 21
    • 11
    • 11
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human AKR1C1 (NP_001344.2).
    Isotype
    IgG
    Top Product
    Discover our top product DDH Primary Antibody
  • Application Notes
    WB 1:1000-1:3000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))
    Alternative Name
    AKR1C1 (DDH Products)
    Synonyms
    2-ALPHA-HSD antibody, 20-ALPHA-HSD antibody, C9 antibody, DD1 antibody, DD1/DD2 antibody, DDH antibody, DDH1 antibody, H-37 antibody, HAKRC antibody, HBAB antibody, MBAB antibody, aldo-keto reductase family 1 member C1 antibody, aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) antibody, AKR1C1 antibody
    Background
    This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
    Molecular Weight

    Observed_MW: 38 kDa

    Calculated_MW: 36 kDa

    Gene ID
    1645
    UniProt
    Q04828
    Pathways
    Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process
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