CCDC98 antibody (AA 51-150)
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- Target See all CCDC98 (FAM175A) Antibodies
- CCDC98 (FAM175A) (Family with Sequence Similarity 175, Member A (FAM175A))
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Binding Specificity
- AA 51-150
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Reactivity
- Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CCDC98 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Cross-Reactivity
- Mouse
- Predicted Reactivity
- Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human CCDC98
- Isotype
- IgG
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anti-Family with Sequence Similarity 175, Member A (FAM175A) (AA 1-313) antibody
FAM175A Reactivity: Human WB, IP, FACS Host: Mouse Monoclonal ABRA1-01 unconjugated
anti-Family with Sequence Similarity 175, Member A (FAM175A) (AA 1-313) antibodyFAM175A Reactivity: Human WB, IP, IHC, IHC (p), FACS Host: Mouse Monoclonal ABRA1-01 unconjugated
anti-Family with Sequence Similarity 175, Member A (FAM175A) (AA 350-400) antibodyFAM175A Reactivity: Human WB, IP, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Family with Sequence Similarity 175, Member A (FAM175A) (N-Term) antibodyFAM175A Reactivity: Human, Mouse WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
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- Application Notes
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- CCDC98 (FAM175A) (Family with Sequence Similarity 175, Member A (FAM175A))
- Alternative Name
- CCDC98 (FAM175A Products)
- Synonyms
- CCDC98 antibody, abra1 antibody, ccdc98 antibody, fam175a antibody, ABRA1 antibody, 3830405G04Rik antibody, 5630400M01Rik antibody, AI506069 antibody, AL024423 antibody, AV118690 antibody, Ccdc98 antibody, RGD1305287 antibody, zgc:103522 antibody, abraxas 1, BRCA1 A complex subunit antibody, Coiled-coil domain-containing protein 98 antibody, BRCA1 A complex subunit antibody, family with sequence similarity 175 member A antibody, abraxas 2a, BRISC complex subunit antibody, abraxas 1, BRCA1 A complex subunit S homeolog antibody, ABRAXAS1 antibody, abraxas1 antibody, Abraxas1 antibody, FAM175A antibody, abraxas2a antibody, abraxas1.S antibody
- Background
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Synonyms: ABRA1, CCDC98, BRCA1-A complex subunit Abraxas, Coiled-coil domain-containing protein 98, Protein FAM175A, FAM175A, UNQ496/PRO1013
Background: Involved in DNA damage response and double-strand break (DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs. This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX.
- Gene ID
- 84142
- UniProt
- Q6UWZ7
- Pathways
- DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
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