ZC3H8 antibody
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- Target See all ZC3H8 Antibodies
- ZC3H8 (Zinc Finger CCCH-Type Containing 8 (ZC3H8))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ZC3H8 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Cross-Reactivity
- Human
- Characteristics
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Rabbit polyclonal antibody to ZC3H8 (zinc finger CCCH-type containing 8)
ZC3H8 antibody [N1C3] - Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human ZC3H8. The exact sequence is proprietary.
- Isotype
- IgG
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anti-Zinc Finger CCCH-Type Containing 8 (ZC3H8) (Internal Region) antibody
ZC3H8 Reactivity: Human, Mouse WB, ELISA, IHC, ICC, IF Host: Rabbit Polyclonal unconjugated
anti-Zinc Finger CCCH-Type Containing 8 (ZC3H8) (AA 52-81), (N-Term) antibodyZC3H8 Reactivity: Human, Mouse WB, FACS Host: Rabbit Polyclonal RB28955 unconjugated
anti-Zinc Finger CCCH-Type Containing 8 (ZC3H8) (Internal Region) antibodyZC3H8 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Zinc Finger CCCH-Type Containing 8 (ZC3H8) (Center) antibodyZC3H8 Reactivity: Human, Mouse, Rat, Monkey WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Zinc Finger CCCH-Type Containing 8 (ZC3H8) (AA 81-130) antibodyZC3H8 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Comment
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Positive Control: A431 , HepG2 , Raji
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.84 mg/mL
- Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- ZC3H8 (Zinc Finger CCCH-Type Containing 8 (ZC3H8))
- Alternative Name
- zinc finger CCCH-type containing 8 (ZC3H8 Products)
- Synonyms
- Zc3hdc8 antibody, DKFZp459D018 antibody, AU020882 antibody, E130108N08Rik antibody, Fliz1 antibody, ZC3HDC8 antibody, zinc finger CCCH type containing 8 antibody, zinc finger CCCH-type containing 8 antibody, Zc3h8 antibody, ZC3H8 antibody
- Background
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Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (By similarity). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.
Cellular Localization: Nucleus - Molecular Weight
- 34 kDa
- Gene ID
- 84524
- UniProt
- Q8N5P1
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