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Cullin 1 antibody (AA 500-776)

Name: Cullin 1 antibody (AA 500-776)
Brand: antibodies-online
SKU: ABIN3015864
Price: 731.45 USD
Availability: InStock

CUL1 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated

Western blot analysis of extracts of K562 cell line, using CUL1 antibody.

Immunohistochemistry of paraffin-embedded rat lung using Cullin 1 Rabbit pAb (ABIN3015863, ABIN3015864, ABIN3015865 and ABIN6219345) at dilution of 1:50 (40x lens).

IHC

Immunofluorescence (IF) image for anti-Cullin 1 (CUL1) (AA 500-776) antibody (ABIN3015864)

Western blot analysis of extracts of various cell lines, using Cullin 1 antibody (ABIN3015863, ABIN3015864, ABIN3015865 and ABIN6219345) at 1:1000 dilution.

Immunohistochemistry of paraffin-embedded human colon using Cullin 1 Rabbit pAb (ABIN3015863, ABIN3015864, ABIN3015865 and ABIN6219345) at dilution of 1:50 (40x lens).

IHC

Immunohistochemistry of paraffin-embedded human lung cancer using Cullin 1 Rabbit pAb (ABIN3015863, ABIN3015864, ABIN3015865 and ABIN6219345) at dilution of 1:50 (40x lens).

IHC

6 images

(2 references)

Catalog No. ABIN3015864

Datasheet as PDF

Target See all Cullin 1 (CUL1) Antibodies

Cullin 1 (CUL1)
Binding Specificity
15

15

8

6

3

2

2

2

2

2

1

1

1

1

1

1
AA 500-776
Reactivity
76

33

28

6

5

5

4

4

4

4

2

2

2

2

1

1
Human
Host
75

1
Rabbit
Compatible Secondaries
Clonality
65

11
Polyclonal
Conjugate
38

5

3

3

3

3

3

3

3

3

2

2

1

1

1

1

1
This Cullin 1 antibody is un-conjugated
Application
42

27

15

14

14

13

12

8

6

3

2

2

1

1

1
Western Blotting (WB), Immunofluorescence (IF)

Sequence

YTSKLQRMFQ DIGVSKDLNE QFKKHLTNSE PLDLDFSIQV LSSGSWPFQQ SCTFALPSEL ERSYQRFTAF YASRHSGRKL TWLYQLSKGE LVTNCFKNRY TLQASTFQMA ILLQYNTEDA YTVQQLTDST QIKMDILAQV LQILLKSKLL VLEDENANVD EVELKPDTLI KLYLGYKNKK LRVNINVPMK TEQKQEQETT HKNIEEDRKL LIQAAIVRIM KMRKVLKHQQ LLGEVLTQLS SRFKPRVPVI KKCIDILIEK EYLERVDGEK DTYSYLA

Cross-Reactivity

Human, Mouse, Rat

Characteristics

Polyclonal Antibodies

Purification

Affinity purification

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 500-776 of human Cullin 1 (NP_003583.2).

Isotype

IgG
anti-Cullin 1 (CUL1) antibody
CUL1 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Cullin 1 (CUL1) antibody
CUL1 Reactivity: Human, Mouse WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Cullin 1 (CUL1) (AA 1-250) antibody
CUL1 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Cullin 1 (CUL1) antibody
CUL1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Cullin 1 (CUL1) (AA 1-776) antibody
CUL1 Reactivity: Human WB, IF, PLA Host: Rabbit Polyclonal unconjugated

anti-Cullin 1 (CUL1) (C-Term) antibody
CUL1 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Cullin 1 (CUL1) (C-Term) antibody
CUL1 Reactivity: Human, Mouse WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Cullin 1 (CUL1) (C-Term) antibody
CUL1 Reactivity: Human WB, ELISA, IHC, IP, IHC (p) Host: Mouse Monoclonal unconjugated

anti-Cullin 1 (CUL1) (C-Term) antibody
CUL1 Reactivity: Human, Mouse, Rat, Chicken, Cow, Dog, Rabbit, Pig WB, IHC, IF, IC Host: Rabbit Polyclonal unconjugated

anti-Cullin 1 (CUL1) (AA 727-776) antibody
CUL1 Reactivity: Human, Mouse WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated

Application Notes

WB,1:500 - 1:2000,IF,1:10 - 1:100

Restrictions

For Research Use only
Buffer

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

-20 °C

Storage Comment

Store at -20°C. Avoid freeze / thaw cycles.
Chen, Xu, Yang, Zhang, Wu, Chen, Li, Wang, Li, Li, Dai: "Upregulation of miR-223 in the rat liver inhibits proliferation of hepatocytes under simulated microgravity." in: Experimental & molecular medicine, Vol. 49, Issue 6, pp. e348, (2018) (PubMed).

Liao, Jiang, He, Ni, Tu, Zhang, Wang, Lou, Quan, Wang: "NEDD8-mediated neddylation is required for human endometrial stromal proliferation and decidualization." in: Human reproduction (Oxford, England), Vol. 30, Issue 7, pp. 1665-76, (2016) (PubMed).
Target

Cullin 1 (CUL1)

Alternative Name

CUL1 (CUL1 Products)

Synonyms

LOC100282292 antibody, Cullin-1 antibody, Cul1 antibody, zgc:55747 antibody, zgc:77500 antibody, wu:fc13a10 antibody, cullin-1 antibody, ATCUL1 antibody, AUXIN RESISTANT 6 antibody, AXR6 antibody, T10P11.26 antibody, T10P11_26 antibody, cullin 1 antibody, cul1 antibody, wu:fi43h07 antibody, wu:fj43a08 antibody, zgc:111899 antibody, zgc:55483 antibody, Cul-1 antibody, cullin 1 antibody, cullin-1 antibody, Cullin 1 antibody, Cullin-1 antibody, cullin 1a antibody, cullin 1 S homeolog antibody, cullin 1b antibody, CUL1 antibody, LOC100282292 antibody, cul1 antibody, ATEG_00491 antibody, EDI_072700 antibody, EDI_264400 antibody, SJAG_02591 antibody, BDBG_03785 antibody, Cul1 antibody, cul1a antibody, cul1.S antibody, cul-1 antibody, cul1b antibody

Background

The cullin family proteins are scaffold proteins for the Ring finger type E3 ligases. Humans express seven cullin proeins: CUL1-3, CUL4A, CUL4B, CUL5, and CUL7. Each cullin protein can form an E3 ligase similar to the prototype Ring-type E3 ligase Skp1-CUL1-F-box complex. The Cullin-RING-finger type E3 ligases are important regulators in early embryonic development, as highlighted by genetic studies demonstrating that knock-out of CUL1, CUL3, or CUL4A in mice results in early embryonic lethality.,Cullin 1,CUL1,cullin-1,MGC149834,MGC149835,Cancer,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Cell cycle inhibitors,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,CUL1

Molecular Weight

89 kDa

Gene ID

8454

UniProt

Q13616

Pathways

Cell Division Cycle, Hedgehog Signaling, Mitotic G1-G1/S Phases, Regulation of Cell Size