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ZFYVE19 antibody (Internal Region)

ZFYVE19 Reactivity: Human, Mouse WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6257582
  • Target See all ZFYVE19 products
    ZFYVE19 (Zinc Finger, FYVE Domain Containing 19 (ZFYVE19))
    Binding Specificity
    • 10
    • 8
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 36
    • 3
    • 3
    • 2
    • 1
    Human, Mouse
    Host
    • 33
    • 3
    Rabbit
    Clonality
    • 33
    • 3
    Polyclonal
    Conjugate
    • 18
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ZFYVE19 antibody is un-conjugated
    Application
    • 29
    • 21
    • 15
    • 6
    • 4
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    ZFYVE19 Antibody detects endogenous levels of total ZFYVE19.
    Predicted Reactivity
    Horse,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human ZFYVE19, corresponding to a region within the internal amino acids.
    Isotype
    IgG
  • Application Notes
    WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    ZFYVE19 (Zinc Finger, FYVE Domain Containing 19 (ZFYVE19))
    Alternative Name
    ZFYVE19 (ZFYVE19 Products)
    Synonyms
    ZFYVE19 antibody, mpfyve antibody, DKFZp469E1112 antibody, MPFYVE antibody, 1500041L05Rik antibody, zinc finger FYVE-type containing 19 antibody, zinc finger FYVE domain containing 19 antibody, zinc finger, FYVE domain containing 19 antibody, ZFYVE19 antibody, Zfyve19 antibody, zfyve19 antibody
    Background

    Description: Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB results in dephosphorylation of CHMP4C followed by its dissociation from ZFYVE19/ANCHR and VPS4 and subsequent abscission.

    Gene: ZFYVE19

    Molecular Weight
    50 kDa
    Gene ID
    84936
    UniProt
    Q96K21
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