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COL18A1 antibody (AA 1572-1754)

COL18A1 Reactivity: Human, Mouse, Rat WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5692837
  • Target See all COL18A1 Antibodies
    COL18A1 (Collagen, Type XVIII, alpha 1 (COL18A1))
    Binding Specificity
    • 15
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1572-1754
    Reactivity
    • 76
    • 47
    • 22
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 76
    • 9
    • 2
    Rabbit
    Clonality
    • 77
    • 11
    Polyclonal
    Conjugate
    • 44
    • 9
    • 7
    • 7
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This COL18A1 antibody is un-conjugated
    Application
    • 74
    • 48
    • 32
    • 15
    • 13
    • 13
    • 6
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Brand
    Picoband™
    Cross-Reactivity (Details)
    No cross reactivity with other proteins.
    Characteristics
    Rabbit IgG polyclonal antibody for COL18A1 detection. Tested with WB, ELISA(Cap) in Human,Mouse,Rat.
    Immunogen
    E. coli-derived human COL18A1 recombinant protein (Position: H1572-K1754).
    Top Product
    Discover our top product COL18A1 Primary Antibody
  • Application Notes

    Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

    Application Details: Western blot, 0.1-0.5 μg/mL
    ELISA(Cap), 1-5 μg/mL

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Buffer
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
  • Target
    COL18A1 (Collagen, Type XVIII, alpha 1 (COL18A1))
    Alternative Name
    COL18A1 (COL18A1 Products)
    Synonyms
    KNO antibody, KNO1 antibody, KS antibody, cb371 antibody, cb529 antibody, fc96d06 antibody, sb:cb529 antibody, wu:fb47h10 antibody, wu:fb77g12 antibody, wu:fc50f04 antibody, wu:fc96d06 antibody, wu:fk02h12 antibody, kno antibody, kno1 antibody, collagen type XVIII alpha 1 chain antibody, collagen type XVIII alpha 1 chain a antibody, collagen, type XVIII, alpha 1 antibody, collagen type XVIII alpha 1 antibody, COL18A1 antibody, col18a1a antibody, Col18a1 antibody, col18a1 antibody
    Background

    Synonyms: Collagen alpha-1(XVIII) chain, Endostatin, COL18A1

    Tissue Specificity: Present in multiple organs with highest levels in liver, lung and kidney.

    Background: Collagen alpha-1(XVIII) chain is a protein that in humans is encoded by the COL18A1 gene. This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. A long isoform of the protein has an N-terminal domain that is homologous to the extracellular part of frizzled receptors. Proteolytic processing at several endogenous cleavage sites in the C-terminal domain results in production of endostatin, a potent antiangiogenic protein that is able to inhibit angiogenesis and tumor growth. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternative splicing results in multiple transcript variants.

    UniProt
    P39060
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