Caveolin-1 antibody (N-Term)
(1 reference)-
- Target See all Caveolin-1 (CAV1) Antibodies
- Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))
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Binding Specificity
- N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Caveolin-1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
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Rabbit polyclonal antibody to Caveolin 1 (caveolin 1, caveolae protein, 22 kDa)
Caveolin 1 antibody [N1N3] - Purification
- Purified by antigen-affinity chromatography.
- Grade
- KO Validated
- Immunogen
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Caveolin 1. The exact sequence is proprietary.
- Isotype
- IgG
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anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (AA 2-104) antibody
CAV1 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (AA 2-104) antibodyCAV1 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (AA 2-105) antibodyCAV1 Reactivity: Rat WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (Internal Region) antibodyVerified CAV1 Reactivity: Human WB, ELISA, IHC, IF, FACS Host: Goat Polyclonal unconjugated
anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (AA 1-100) antibodyCAV1 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (AA 2-120) antibodyCAV1 Reactivity: Human, Rat, Mouse WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro), FACS Host: Rabbit Polyclonal unconjugated
anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (AA 4-178) antibodyCAV1 Reactivity: Human, Mouse WB, IHC (p), ICC, IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (AA 4-178) antibodyCAV1 Reactivity: Human, Mouse WB, IF, IHC (p), ICC, IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (N-Term) antibodyCAV1 Reactivity: Human, Rat, Mouse WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (C-Term) antibodyCAV1 Reactivity: Human, Mouse WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Comment
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Positive Control: A431 , H1299 , HeLa , mouse lung , HeLa
Validation: KO/KD, Orthogonal
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "A novel c-Kit/phospho-prohibitin axis enhances ovarian cancer stemness and chemoresistance via Notch3-PBX1 and β-catenin-ABCG2 signaling." in: Journal of biomedical science, Vol. 27, Issue 1, pp. 42, (2020) (PubMed).
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: "A novel c-Kit/phospho-prohibitin axis enhances ovarian cancer stemness and chemoresistance via Notch3-PBX1 and β-catenin-ABCG2 signaling." in: Journal of biomedical science, Vol. 27, Issue 1, pp. 42, (2020) (PubMed).
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- Target
- Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))
- Alternative Name
- caveolin 1 (CAV1 Products)
- Background
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The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene.
Cellular Localization: Golgi apparatus membrane , Cell membrane , Membrane , caveola - Molecular Weight
- 20 kDa
- Gene ID
- 857
- UniProt
- Q03135
- Pathways
- Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of Transporter Activity, VEGFR1 Specific Signals
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