PPAP2A antibody (C-Term)
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- Target See all PPAP2A Antibodies
- PPAP2A (Phosphatidic Acid Phosphatase Type 2A (PPAP2A))
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Binding Specificity
- AA 270-304, C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PPAP2A antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This PPAP2A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 270-304 amino acids from the C-terminal region of human PPAP2A.
- Clone
- RB51855
- Isotype
- Ig Fraction
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anti-Phosphatidic Acid Phosphatase Type 2A (PPAP2A) (AA 1-284) antibody
PPAP2A Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Phosphatidic Acid Phosphatase Type 2A (PPAP2A) (AA 31-80) antibodyPPAP2A Reactivity: Human, Rat, Guinea Pig, Monkey WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Phosphatidic Acid Phosphatase Type 2A (PPAP2A) (AA 1-284) antibodyPPAP2A Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-Phosphatidic Acid Phosphatase Type 2A (PPAP2A) (N-Term) antibodyPPAP2A Reactivity: Human, Rat, Mouse, Guinea Pig WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Phosphatidic Acid Phosphatase Type 2A (PPAP2A) (Middle Region) antibodyPPAP2A Reactivity: Human, Rat, Mouse, Guinea Pig, Dog, Horse, Zebrafish (Danio rerio), Cow, Rabbit WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Phosphatidic Acid Phosphatase Type 2A (PPAP2A) (AA 136-185) antibodyPPAP2A Reactivity: Human, Rat, Mouse, Guinea Pig, Dog, Horse, Zebrafish (Danio rerio), Cow, Monkey, Bat, Chicken, Pig, Xenopus laevis WB Host: Rabbit Polyclonal unconjugated
anti-Phosphatidic Acid Phosphatase Type 2A (PPAP2A) (AA 35-84) antibodyPPAP2A Reactivity: Human, Mouse, Guinea Pig, Dog, Horse, Monkey, Bat WB Host: Rabbit Polyclonal unconjugated
anti-Phosphatidic Acid Phosphatase Type 2A (PPAP2A) (AA 1-100) antibodyPPAP2A Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB: 1:1000. WB: 1:1000. WB: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Expiry Date
- 6 months
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- Target
- PPAP2A (Phosphatidic Acid Phosphatase Type 2A (PPAP2A))
- Alternative Name
- PPAP2A (PPAP2A Products)
- Synonyms
- PPAP2A antibody, wun antibody, LLP1a antibody, LPP1 antibody, PAP-2a antibody, PAP2 antibody, Hic53 antibody, Hpic53 antibody, LPP-1 antibody, mPAP antibody, PAP2A antibody, PAP2a2 antibody, phospholipid phosphatase 1 antibody, phosphatidic acid phosphatase type 2A antibody, phospholipid phosphatase 1 L homeolog antibody, PLPP1 antibody, plpp1 antibody, Ppap2a antibody, plpp1.L antibody, Plpp1 antibody
- Background
- Broad-specificity phosphohydrolase that dephosphorylates exogenous bioactive glycerolipids and sphingolipids. Catalyzes the conversion of phosphatidic acid (PA) to diacylglycerol (DG). Pivotal regulator of lysophosphatidic acid (LPA) signaling in the cardiovascular system. Major enzyme responsible of dephosphorylating LPA in platelets, which terminates signaling actions of LPA. May control circulating, and possibly also regulate localized, LPA levels resulting from platelet activation. It has little activity towards ceramide-1-phosphate (C-1-P) and sphingosine-1-phosphate (S-1-P). The relative catalytic efficiency is LPA > PA > S-1-P > C-1-P. It's down-regulation may contribute to the development of colon adenocarcinoma.
- Molecular Weight
- 32156
- UniProt
- O14494
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway
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