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NCOA1 antibody (AA 1222-1441)

NCOA1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3021492
  • Target See all NCOA1 Antibodies
    NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))
    Binding Specificity
    • 15
    • 7
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1222-1441
    Reactivity
    • 65
    • 46
    • 18
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 72
    • 8
    Rabbit
    Clonality
    • 63
    • 17
    Polyclonal
    Conjugate
    • 40
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This NCOA1 antibody is un-conjugated
    Application
    • 52
    • 16
    • 13
    • 13
    • 12
    • 8
    • 7
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    NPQMQQNVFQ YPGAGMVPQG EANFAPSLSP GSSMVPMPIP PPQSSLLQQT PPASGYQSPD MKAWQQGAIG NNNVFSQAVQ NQPTPAQPGV YNNMSITVSM AGGNTNVQNM NPMMAQMQMS SLQMPGMNTV CPEQINDPAL RHTGLYCNQL SSTDLLKTEA DGTQQVQQVQ VFADVQCTVN LVGGDPYLNQ PGPLGTQKPT SGPQTPQAQQ KSLLQQLLTE
    Cross-Reactivity
    Human, Mouse
    Characteristics
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1222-1441 of human NCOA1 (NP_003734.3).
    Isotype
    IgG
  • Application Notes
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid freeze / thaw cycles
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))
    Alternative Name
    NCOA1 (NCOA1 Products)
    Synonyms
    F-SRC-1 antibody, KAT13A antibody, RIP160 antibody, SRC1 antibody, bHLHe42 antibody, bHLHe74 antibody, si:dkey-5g7.6 antibody, si:dkey-34f16.6 antibody, NCOA1 antibody, SRC-1 antibody, nuclear receptor coactivator 1 antibody, NCOA1 antibody, ncoa1 antibody, Ncoa1 antibody
    Background
    The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified.,NCOA1,F-SRC-1,KAT13A,RIP160,SRC1,bHLHe42,bHLHe74,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Acetylation,Nuclear Receptor Signaling,Nuclear hormone receptors,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,NCOA1
    Molecular Weight
    152 kDa/156 kDa
    Gene ID
    8648
    UniProt
    Q15788
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
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