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Beclin 1 antibody (AA 201-330)

Name: Beclin 1 antibody (AA 201-330)
SKU: ABIN675384
Price: 384.62 USD
Availability: InStock

BECN1 Reactivity: Human, Mouse, Rat WB, ELISA, FACS, IHC (p), ICC, IF (p), IF (cc), IHC (fro) Host: Rabbit Polyclonal unconjugated

293T lyates probed with Rabbit Anti-Beclin 1 Polyclonal Antibody, Unconjugated at 1:300 in 4˚C overnight.

Lane 1: mouse brain lysates Lane 2: mouse intestine lysates probed with Anti BECN1/Beclin 1/ATG6 Polyclonal Antibody, Unconjugated (ABIN675384) at 1:200 in 4C.

SDS

Formalin-fixed and paraffin embedded rat kidney labeled with Anti-Beclin 1/ATG6 Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining

IHC (p)

Formalin-fixed and paraffin-embedded rat stomach labeled with Anti-Beclin 1/ATG6 Polyclonal Antibody, Unconjugatedused at 1:200 dilution for 40 minutes at 37°C.

Formalin-fixed and paraffin embedded rabbit myocardium labeled with Anti-BECN1/Beclin 1/ATG6 Polyclonal Antibody, Unconjugated (ABIN675384) followed by conjugation to the secondary antibody and DAB staining

IHC

Formalin-fixed and paraffin embedded rat brain labeled with Anti-Beclin 1/ATG6 Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining

IHC (p)

Image provided by One World Lab validation program.

IF (cc)

8 images

(11 references)

Catalog No. ABIN675384

Datasheet as PDF

Target See all Beclin 1 (BECN1) Antibodies

Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))
Binding Specificity
15

15

15

9

9

9

8

8

8

8

8

7

7

6

6

6

6

6

6

6

6

6

5

4

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 201-330
Reactivity
202

87

71

10

9

7

5

5

4

3

3

2

2

2

1

1

1

1
Human, Mouse, Rat
Host
171

34

2
Rabbit
Compatible Secondaries
Clonality
170

37
Polyclonal
Conjugate
91

18

16

15

14

14

4

4

4

4

4

4

2

2

2

2

2

1

1

1

1

1
This Beclin 1 antibody is un-conjugated
Application
147

98

61

37

31

26

25

22

19

13

12

4

3

2
Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity

Human, Mouse, Rat

Predicted Reactivity

Dog,Cow,Pig,Horse,Rabbit

Purification

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from human Beclin 1

Isotype

IgG
anti-Beclin 1, Autophagy Related (BECN1) (AA 210-239) antibody
BECN1 Reactivity: Human, Mouse WB, FACS, IHC (p) Host: Rabbit Polyclonal RB7463 unconjugated

anti-Beclin 1, Autophagy Related (BECN1) antibody
BECN1 Reactivity: Human, Rat, Dog WB, IHC, IF, FACS, IHC (p) Host: Mouse Monoclonal 1F1 unconjugated

anti-Beclin 1, Autophagy Related (BECN1) antibody
BECN1 Reactivity: Human WB, ELISA, IHC, FACS Host: Mouse Monoclonal 2A4 unconjugated

anti-Beclin 1, Autophagy Related (BECN1) antibody
BECN1 Reactivity: Human, Rat, Monkey, Dog WB, IHC, IF, FACS, IHC (p) Host: Mouse Monoclonal 3C3 unconjugated

anti-Beclin 1, Autophagy Related (BECN1) antibody
BECN1 Reactivity: Human, Rat, Monkey WB, IHC, IF, FACS, IHC (p) Host: Mouse Monoclonal 3F3 unconjugated

anti-Beclin 1, Autophagy Related (BECN1) (AA 1-354) antibody
BECN1 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-Beclin 1, Autophagy Related (BECN1) (AA 210-239) antibody
BECN1 Reactivity: Human, Mouse WB, ELISA, IHC, FACS Host: Rabbit Polyclonal unconjugated

anti-Beclin 1, Autophagy Related (BECN1) (AA 181-210) antibody
BECN1 Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB7461 unconjugated

anti-Beclin 1, Autophagy Related (BECN1) (C-Term) antibody
BECN1 Reactivity: Human, Mouse WB, ELISA, IHC, IHC (p), ICC Host: Rabbit Polyclonal unconjugated

anti-Beclin 1, Autophagy Related (BECN1) (AA 95-132) antibody
BECN1 Reactivity: Human, Mouse WB, ELISA, IHC, FACS Host: Rabbit Polyclonal unconjugated

Application Notes

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions

For Research Use only
Format

Liquid

Concentration

1 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative

ProClin

Precaution of Use

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage

4 °C,-20 °C

Storage Comment

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date

12 months
Chen, Chen, Wu, Chou, Chen, Wei, Lee, Hong, Zheng, Chiu, Lin, Hsu, Hsu: "Far-infrared protects vascular endothelial cells from advanced glycation end products-induced injury via PLZF-mediated autophagy in diabetic mice." in: Scientific reports, Vol. 7, pp. 40442, (2017) (PubMed).

Yang, Wu, Feng, Huang, Liu, Liu, Chen: "Vitamin C plus hydrogel facilitates bone marrow stromal cell-mediated endometrium regeneration in rats." in: Stem cell research & therapy, Vol. 8, Issue 1, pp. 267, (2017) (PubMed).

Tian, Liu, Qu: "Role of endoplasmic reticulum stress on cisplatin resistance in ovarian carcinoma." in: Oncology letters, Vol. 13, Issue 3, pp. 1437-1443, (2017) (PubMed).

Sun, Nie, Wang, Yang, Meng, Xiao, Xiang, Li, Fu, Wang: "Factors that Affect Pancreatic Islet Cell Autophagy in Adult Rats: Evaluation of a Calorie-Restricted Diet and a High-Fat Diet." in: PLoS ONE, Vol. 11, Issue 3, pp. e0151104, (2016) (PubMed).

Han, Hu, Qi, Ma, Wang, Ma, Tao, Qin: "Polysaccharides from Polygonatum Inhibit the Proliferation of Prostate Cancer-Associated Fibroblasts." in: Asian Pacific journal of cancer prevention : APJCP, Vol. 17, Issue 8, pp. 3829-33, (2016) (PubMed).

Zhang, Ma, Qi, Wei, Zhang, Li, Chiu: "P62 regulates resveratrol-mediated Fas/Cav-1 complex formation and transition from autophagy to apoptosis." in: Oncotarget, Vol. 6, Issue 2, pp. 789-801, (2015) (PubMed).

Liu, Tang, Zhang, Li, Yuan, Wang: "Autophagy activation aggravates neuronal injury in the hippocampus of vascular dementia rats." in: Neural regeneration research, Vol. 9, Issue 13, pp. 1288-96, (2014) (PubMed).

Chen, Wei, Nie, Lin, Tian, Liu, Yu, Cheng, Yan, Wang, Liu, Deng, Lai, Zhou, Zhang, Lin, Chen: "?-Asarone prevents autophagy and synaptic loss by reducing ROCK expression in asenescence-accelerated prone 8 mice." in: Brain research, Vol. 1552, pp. 41-54, (2014) (PubMed).

Tang, Li, Wei, Zhang, Chiu, Hasenmayer, Zhang, Zhang: "Resveratrol-induced apoptosis is enhanced by inhibition of autophagy in esophageal squamous cell carcinoma." in: Cancer letters, Vol. 336, Issue 2, pp. 325-37, (2013) (PubMed).

Wang, Niu, Shi, Gao, Wang, Han, Li, Gao, Zhu, Song, Qin, Wang: "Bcl-3, induced by Tax and HTLV-1, inhibits NF-?B activation and promotes autophagy." in: Cellular signalling, Vol. 25, Issue 12, pp. 2797-804, (2013) (PubMed).

Banerjee, Basu, Wegiel, Otterbein, Mizumura, Gasser, Waaga-Gasser, Choi, Pal: "Heme oxygenase-1 promotes survival of renal cancer cells through modulation of apoptosis- and autophagy-regulating molecules." in: The Journal of biological chemistry, Vol. 287, Issue 38, pp. 32113-23, (2012) (PubMed).
Target

Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))

Alternative Name

Beclin 1 (BECN1 Products)

Synonyms

beclin-1 antibody, atg6 antibody, vps30 antibody, beclin1 antibody, Beclin-1 antibody, becn1 antibody, zgc:73097 antibody, ATG6 antibody, VPS30 antibody, 4921513J16Rik antibody, 5430417M23Rik antibody, Atg6 antibody, beclin 1 antibody, beclin 1, autophagy related antibody, beclin 1 protein antibody, beclin-1 antibody, beclin family protein antibody, beclin 1, autophagy related L homeolog antibody, BECN1 antibody, becn1 antibody, atg6 antibody, CpipJ_CPIJ011087 antibody, PTRG_07825 antibody, SJAG_01876 antibody, Becn1 antibody, becn1.L antibody

Background

Synonyms: ATG6, VPS3, beclin1, Beclin-1, Coiled-coil myosin-like BCL2-interacting protein, Protein GT197, BECN1, GT197
Background: Plays a central role in autophagy. Required for the abcission step in cytokinesis. May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus.

Gene ID

8678

UniProt

Q14457

Pathways

Autophagy