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MARCO antibody (AA 13-40)

MARCO Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB24662 unconjugated
Catalog No. ABIN653847
  • Target See all MARCO Antibodies
    MARCO (Macrophage Receptor with Collagenous Structure (MARCO))
    Binding Specificity
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 13-40
    Reactivity
    • 13
    • 6
    • 3
    • 2
    • 1
    • 1
    Human
    Host
    • 11
    • 3
    • 1
    • 1
    Rabbit
    Clonality
    • 11
    • 4
    • 1
    Polyclonal
    Conjugate
    • 15
    • 1
    This MARCO antibody is un-conjugated
    Application
    • 14
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This MARCO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-40 amino acids of human MARCO.
    Clone
    RB24662
    Isotype
    IgG
    Top Product
    Discover our top product MARCO Primary Antibody
  • Application Notes
    WB: 1:500. IHC-P: 1:50~100. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Ohta, Moriyama, Maehara, Gion, Furukawa, Tanaka, Hayashida, Yamauchi, Ishiguro, Mikami, Tsuboi, Iizuka-Koga, Kawano, Sato, Kiyoshima, Sumida, Nakamura: "DNA Microarray Analysis of Submandibular Glands in IgG4-Related Disease Indicates a Role for MARCO and Other Innate Immune-Related Proteins." in: Medicine, Vol. 95, Issue 7, pp. e2853, (2016) (PubMed).

    Chao, Makale, Karmali, Sharikov, Tsigelny, Merkulov, Kesari, Wrasidlo, Ruoslahti, Simberg: "Recognition of dextran-superparamagnetic iron oxide nanoparticle conjugates (Feridex) via macrophage scavenger receptor charged domains." in: Bioconjugate chemistry, Vol. 23, Issue 5, pp. 1003-9, (2014) (PubMed).

  • Target
    MARCO (Macrophage Receptor with Collagenous Structure (MARCO))
    Alternative Name
    MARCO (MARCO Products)
    Background
    MARCO is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains.
    Molecular Weight
    52658
    Gene ID
    8685
    NCBI Accession
    NP_006761
    UniProt
    Q9UEW3
    Pathways
    Activation of Innate immune Response
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