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Cathepsin F antibody (AA 261-290)

CTSF Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB19248 unconjugated
Catalog No. ABIN390488
  • Target See all Cathepsin F (CTSF) Antibodies
    Cathepsin F (CTSF)
    Binding Specificity
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 261-290
    Reactivity
    • 31
    • 12
    • 2
    • 1
    Human
    Host
    • 29
    • 2
    • 1
    • 1
    Rabbit
    Clonality
    • 31
    • 2
    Polyclonal
    Conjugate
    • 14
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Cathepsin F antibody is un-conjugated
    Application
    • 15
    • 12
    • 10
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This CTSF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 261-290 amino acids from the Central region of human CTSF.
    Clone
    RB19248
    Isotype
    Ig Fraction
    Top Product
    Discover our top product CTSF Primary Antibody
  • Application Notes
    WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    Cathepsin F (CTSF)
    Alternative Name
    CTSF (CTSF Products)
    Synonyms
    CTSF antibody, MGC140519 antibody, cb420 antibody, sb:cb420 antibody, zgc:153093 antibody, LOC100101596 antibody, Ctsf antibody, ACYPI000376 antibody, catf antibody, CATSF antibody, CLN13 antibody, AI481912 antibody, cathepsin F antibody, cathepsin W antibody, CTSF antibody, ctsf antibody, Ctsf antibody, ctsw antibody, Tsp_02382 antibody
    Background
    Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. Cathepsins generally contain a signal sequence, followed by a propeptide and then a catalytically active mature region. The very long (251 amino acid residues) proregion of the cathepsin F precursor contains a C-terminal domain similar to the pro-segment of cathepsin L-like enzymes, a 50-residue flexible linker peptide, and an N-terminal domain predicted to adopt a cystatin-like fold. The cathepsin F proregion is unique within the papain family cysteine proteases in that it contains this additional N-terminal segment predicted to share structural similarities with cysteine protease inhibitors of the cystatin superfamily. This cystatin-like domain contains some of the elements known to be important for inhibitory activity. CTSF is a predicted protein of 484 amino acids which contains a 19 residue signal peptide. Cathepsin F contains five potential N-glycosylation sites, and it may be targeted to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway.
    Molecular Weight
    53366
    Gene ID
    8722
    NCBI Accession
    NP_003784
    UniProt
    Q9UBX1
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