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TNFRSF6B antibody

TNFRSF6B Reactivity: Human, Mouse, Rat WB, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7076071
  • Target See all TNFRSF6B Antibodies
    TNFRSF6B (Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B))
    Reactivity
    Human, Mouse, Rat
    Host
    • 39
    • 7
    Rabbit
    Clonality
    • 39
    • 7
    Polyclonal
    Conjugate
    • 24
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TNFRSF6B antibody is un-conjugated
    Application
    • 30
    • 25
    • 24
    • 19
    • 8
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Mouse, Rat
    Purification
    Affinity purification
    Immunogen
    Recombinant protein corresponding to Human DcR3
  • Application Notes
    WB (H,M,R) 1:500-1:1000, IHC/IF (H,M,R) 1:700-1:1400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Target
    TNFRSF6B (Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B))
    Alternative Name
    DcR3 (TNFRSF6B Products)
    Synonyms
    DCR3 antibody, DJ583P15.1.1 antibody, M68 antibody, M68E antibody, TR6 antibody, dcr3 antibody, m68 antibody, tr6 antibody, TNF receptor superfamily member 6b antibody, tumor necrosis factor receptor superfamily, member 11b antibody, regulator of telomere elongation helicase 1 antibody, TNF receptor superfamily member 6b L homeolog antibody, TNFRSF6B antibody, tnfrsf11b antibody, RTEL1 antibody, tnfrsf6b antibody, tnfrsf6b.L antibody
    Background
    Several novel members in the TNFR family including DR3, DR4, DR5, and DR6 were recently discovered and function as cell death receptors. Two decoy receptors, DcR1 and DcR2, were recently identified to compete with DR4 and DR5 for their ligand TRAIL binding. A novel decoy receptor was more recently discovered and designated DcR3 and TR6, respectively. Unlike DcR1and DcR2, DcR3 is a soluble rather than a membraneassociated molecule. DcR3 binds to FasL and LIGHT andinhibits FasL and LIGHT induced apoptosis. DcR3 transcript is expressed in a number of lung and coloncarcinomas and in some normal tissues.
    Molecular Weight
    33 kDa
    Gene ID
    8771
    NCBI Accession
    NP_003814
    UniProt
    O95407
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