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CES2 antibody (AA 340-369)

Name: CES2 antibody (AA 340-369)
SKU: ABIN654618
Price: 429 USD
Availability: InStock

CES2 Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB18998 unconjugated

CES2 Antibody (Center) (ABIN654618 and ABIN2844316) western blot analysis in MCF-7 cell line lysates (35 μg/lane).

Overlay histogram showing MCF-7 cells stained with (ABIN654618 and ABIN2844316) (green line).

FACS

All lanes : Anti-CES2 Antibody (Center) at 1:2000 dilution Lane 1: S whole cell lysates Lane 2: human liver lysates Lysates/proteins at 20 μg per lane.

All lanes : Anti-CES2 Antibody (Center) at 1:2000 dilution Lane 1: HepG2 whole cell lysates Lane 2: human liver lysates Lysates/proteins at 20 μg per lane.

CES2 antibody (Center) (ABIN654618 and ABIN2844316) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.

IHC (p)

Overlay histogram showing U-87 MG cells stained with (ABIN654618 and ABIN2844316) (green line).

FACS

6 images

(2 references)

Catalog No. ABIN654618

Datasheet as PDF

Target See all CES2 Antibodies

CES2 (Carboxylesterase 2 (CES2))
Binding Specificity
7

7

6

5

4

3

2

2

2

1

1

1

1

1

1

1

1
AA 340-369
Reactivity
45

9

3

3

1

1
Human
Host
39

7

3

1
Rabbit
Compatible Secondaries
Clonality
46

4
Polyclonal
Conjugate
33

3

2

2

2

2

1

1

1

1

1

1
This CES2 antibody is un-conjugated
Application
41

26

24

11

9

6

5

4

1

1
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen

This CES2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 340-369 amino acids from the Central region of human CES2.

Clone

RB18998

Isotype

Ig Fraction
anti-Carboxylesterase 2 (CES2) (AA 514-621) antibody
CES2 Reactivity: Human WB, ELISA, IHC (p) Host: Mouse Monoclonal 4F12 unconjugated

anti-Carboxylesterase 2 (CES2) (C-Term) antibody
CES2 Reactivity: Human, Mouse, Rat, Dog, Guinea Pig WB, IHC Host: Rabbit Polyclonal unconjugated

anti-Carboxylesterase 2 (CES2) (N-Term) antibody
CES2 Reactivity: Human, Mouse WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Carboxylesterase 2 (CES2) (C-Term) antibody
CES2 Reactivity: Human WB, IHC, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-Carboxylesterase 2 (CES2) antibody
CES2 Reactivity: Human WB, IF, IHC (p), ICC Host: Rabbit Polyclonal unconjugated

anti-Carboxylesterase 2 (CES2) (AA 310-522) antibody
CES2 Reactivity: Human WB, IHC, IF, IHC (p), ICC Host: Rabbit Polyclonal unconjugated

anti-Carboxylesterase 2 (CES2) (AA 310-410) antibody
CES2 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated

anti-Carboxylesterase 2 (CES2) antibody
CES2 Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated

anti-Carboxylesterase 2 (CES2) antibody
CES2 Reactivity: Human, Mouse IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Carboxylesterase 2 (CES2) (AA 1-623) antibody
CES2 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated

Application Notes

WB: 1:1000. WB: 1:2000. WB: 1:2000. IHC-P: 1:50~100. FC: 1:25. FC: 1:25

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C,-20 °C

Storage Comment

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date

6 months
Shang, Liu, Chen, Ning, Xiong, Liu, Mao, Hu, Yang: "Fluoxetine reduces CES1, CES2, and CYP3A4 expression through decreasing PXR and increasing DEC1 in HepG2 cells." in: Xenobiotica; the fate of foreign compounds in biological systems, pp. 1-13, (2015) (PubMed).

Chen, Wang, Ning, Hu, Liu, Xiong, Wu, Liu, Hu, Yang: "Decreased carboxylesterases expression and hydrolytic activity in type 2 diabetic mice through Akt/mTOR/HIF-1?/Stra13 pathway." in: Xenobiotica; the fate of foreign compounds in biological systems, pp. 1-12, (2015) (PubMed).
Target

CES2 (Carboxylesterase 2 (CES2))

Alternative Name

CES2 (CES2 Products)

Synonyms

CE-2 antibody, CES2A1 antibody, PCE-2 antibody, iCE antibody, Ces2 antibody, im:6908784 antibody, si:dkey-38l12.2 antibody, zgc:153863 antibody, ce-2 antibody, ces2a1 antibody, pce-2 antibody, carboxylesterase 2 antibody, liver carboxylesterase 2 antibody, cocaine esterase antibody, carboxylesterase 2 (intestine, liver) antibody, CES2 antibody, Ces2 antibody, LOC100343300 antibody, LOC100734360 antibody, ces2 antibody

Background

CES2 is a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance.

Molecular Weight

61807

Gene ID

8824

NCBI Accession

NP_003860, NP_932327

UniProt

O00748