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MAP3K6 antibody (C-Term)

MAP3K6 Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB0946 unconjugated
Catalog No. ABIN392411
  • Target See all MAP3K6 Antibodies
    MAP3K6 (Mitogen-Activated Protein Kinase Kinase Kinase 6 (MAP3K6))
    Binding Specificity
    • 8
    • 7
    • 7
    • 7
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1028-1058, C-Term
    Reactivity
    • 43
    • 26
    • 3
    Human, Mouse
    Host
    • 43
    • 2
    • 1
    Rabbit
    Clonality
    • 45
    • 1
    Polyclonal
    Conjugate
    • 15
    • 6
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MAP3K6 antibody is un-conjugated
    Application
    • 33
    • 31
    • 31
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This MEKK6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1028-1058 amino acids from the C-terminal region of human MEKK6.
    Clone
    RB0946
    Isotype
    Ig Fraction
  • Application Notes
    WB: 1:1000. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Han, Oh, Kang, Kim, Seo, Kim, Park, Kim: "Protein profiling in human sera for identification of potential lung cancer biomarkers using antibody microarray." in: Proteomics, Vol. 9, Issue 24, pp. 5544-52, (2009) (PubMed).

  • Target
    MAP3K6 (Mitogen-Activated Protein Kinase Kinase Kinase 6 (MAP3K6))
    Alternative Name
    MEKK6 (MAP3K6 Products)
    Synonyms
    ASK2 antibody, MAPKKK6 antibody, MEKK6 antibody, Ask2 antibody, mitogen-activated protein kinase kinase kinase 6 antibody, MAP3K6 antibody, Map3k6 antibody
    Background
    Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MEKK6 activates the JNK, but not ERK or p38 kinase pathways.
    Molecular Weight
    142596
    Gene ID
    9064
    NCBI Accession
    NP_004663
    UniProt
    O95382
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