CREB3L1 antibody (AA 396-500)
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- Target See all CREB3L1 Antibodies
- CREB3L1 (CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1))
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Binding Specificity
- AA 396-500
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CREB3L1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Cyclic AMP-responsive element-binding protein 3-like protein 1 protein (396-500AA)
- Isotype
- IgG
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anti-CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1) (AA 481-509), (C-Term) antibody
CREB3L1 Reactivity: Human, Mouse WB, IHC (p), FACS Host: Rabbit Polyclonal RB19585 unconjugated
anti-CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1) (C-Term) antibodyVerified CREB3L1 Reactivity: Human WB, ELISA, IHC Host: Goat Polyclonal unconjugated
anti-CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1) (C-Term) antibodyCREB3L1 Reactivity: Human WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1) (N-Term) antibodyCREB3L1 Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated
anti-CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1) (C-Term) antibodyCREB3L1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1) (AA 1-519) antibodyCREB3L1 Reactivity: Human WB, IF Host: Mouse Polyclonal unconjugated
anti-CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1) antibodyCREB3L1 Reactivity: Human, Mouse WB, IHC, FACS Host: Rabbit Polyclonal unconjugated
anti-CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1) (AA 488-517), (C-Term) antibodyCREB3L1 Reactivity: Human, Mouse WB, IHC (p), FACS, EIA Host: Rabbit Polyclonal unconjugated
anti-CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1) (AA 1-519) antibodyCREB3L1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1) (AA 43-92) antibodyCREB3L1 Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Horse, Monkey, Bat WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Recommended dilution: WB:1:200-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- CREB3L1 (CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1))
- Alternative Name
- CREB3L1 (CREB3L1 Products)
- Synonyms
- CREB3L1 antibody, OASIS antibody, Oasis antibody, diacylglycerol kinase-like antibody, cAMP responsive element binding protein 3 like 1 antibody, cAMP responsive element binding protein 3-like 1 antibody, LOC423198 antibody, CREB3L1 antibody, Creb3l1 antibody
- Background
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Background: Transcription factor involved in unfolded protein response (UPR). In the absence of endoplasmic reticulum (ER) stress, inserted into ER membranes, with N-terminal DNA-binding and transcription activation domains oriented toward the cytosolic face of the membrane. In response to ER stress, transported to the Golgi, where it is cleaved in a site-specific manner by resident proteases S1P/MBTPS1 and S2P/MBTPS2. The released N-terminal cytosolic domain is translocated to the nucleus to effect transcription of specific target genes. Plays a critical role in bone formation through the transcription of COL1A1, and possibly COL1A2, and the secretion of bone matrix proteins. Directly binds to the UPR element (UPRE)-like sequence in an osteoblast-specific COL1A1 promoter region and induces its transcription. Does not regulate COL1A1 in other tissues, such as skin (By similarity). Required to protect astrocytes from ER stress-induced cell death. In astrocytes, binds to the cAMP response element (CRE) of the BiP/HSPA5 promoter and participate in its transcriptional activation (By similarity). May play a role in limiting virus spread by inhibiting proliferation of virus-infected cells. Upon infection with diverse DNA and RNA viruses, inhibits cell-cycle progression by binding to promoters and activating transcription of genes encoding cell-cycle inhibitors, such as p21/CDKN1A (PubMed:21767813). Binds the DNA consensus sequence 5\\\'-GTGXGCXGC-3\\\' (PubMed:21767813).
Aliases: BBF-2 homolog antibody, CAMP responsive element binding protein 3 like 1 antibody, cAMP-responsive element-binding protein 3-like protein 1 antibody, CR3L1_HUMAN antibody, Creb3l1 antibody, Cyclic AMP responsive element binding protein 3 like protein 1 antibody, OASIS antibody, Old astrocyte specifically-induced substance antibody, Processed cyclic AMP-responsive element-binding protein 3-like protein 1 antibody
- UniProt
- Q96BA8
- Pathways
- Thyroid Hormone Synthesis, Chromatin Binding
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