NLRP12 antibody (N-Term)
(1 reference)-
- Target See all NLRP12 Antibodies
- NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))
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Binding Specificity
- AA 183-212, N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NLRP12 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This NLRP12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 183-212 amino acids from the N-terminal region of human NLRP12.
- Clone
- RB33963
- Isotype
- Ig Fraction
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anti-NLR Family, Pyrin Domain Containing 12 (NLRP12) (AA 1-110) antibody
NLRP12 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 4B9 unconjugated
anti-NLR Family, Pyrin Domain Containing 12 (NLRP12) antibodyNLRP12 Reactivity: Human, Mouse WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 12 (NLRP12) (AA 183-212) antibodyNLRP12 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 12 (NLRP12) (Internal Region) antibodyVerified NLRP12 Reactivity: Mouse WB, ELISA Host: Goat Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 12 (NLRP12) (AA 862-1062) antibodyNLRP12 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 12 (NLRP12) (AA 862-1062) antibodyNLRP12 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 12 (NLRP12) antibodyNLRP12 Reactivity: Mouse WB, ELISA Host: Mouse Monoclonal 228CT4-1-3 unconjugated
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- Application Notes
- WB: 1:1000. IHC-P: 1:10~50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- NLRP12 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
- Expiry Date
- 6 months
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: "NLRP12 modulates host defense through IL-17A-CXCL1 axis." in: Mucosal immunology, (2015) (PubMed).
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: "NLRP12 modulates host defense through IL-17A-CXCL1 axis." in: Mucosal immunology, (2015) (PubMed).
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- Target
- NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))
- Alternative Name
- NLRP12 (NLRP12 Products)
- Synonyms
- Nalp12 antibody, NALP12 antibody, CLR19.3 antibody, FCAS2 antibody, PAN6 antibody, PYPAF7 antibody, RNO antibody, RNO2 antibody, NLR family, pyrin domain containing 12 antibody, NLR family pyrin domain containing 12 antibody, NACHT, LRR and PYD domains-containing protein 3 antibody, Nlrp12 antibody, NLRP12 antibody, LOC100018508 antibody
- Background
- This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Alternatively spliced transcript variants encoding distinct isoforms have been described but the full-length nature of some of these has not been determined.
- Molecular Weight
- 120173
- Gene ID
- 91662
- NCBI Accession
- NP_001264055, NP_001264058, NP_653288
- UniProt
- P59046
- Pathways
- Positive Regulation of Endopeptidase Activity, Inflammasome
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