CABLES1 antibody (C-Term)
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- Target See all CABLES1 Antibodies
- CABLES1 (Cdk5 and Abl Enzyme Substrate 1 (CABLES1))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CABLES1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- Ik3-1 Antibody detects endogenous levels of total Ik3-1.
- Predicted Reactivity
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human Ik3-1, corresponding to a region within C-terminal amino acids.
- Isotype
- IgG
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anti-Cdk5 and Abl Enzyme Substrate 1 (CABLES1) (AA 1-368) antibody
CABLES1 Reactivity: Human WB, IF Host: Mouse Polyclonal unconjugated
anti-Cdk5 and Abl Enzyme Substrate 1 (CABLES1) (C-Term) antibodyCABLES1 Reactivity: Human, Mouse, Rat WB, IHC, IF, IC Host: Rabbit Polyclonal unconjugated
anti-Cdk5 and Abl Enzyme Substrate 1 (CABLES1) (C-Term) antibodyCABLES1 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Cdk5 and Abl Enzyme Substrate 1 (CABLES1) (C-Term) antibodyCABLES1 Reactivity: Human, Mouse WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Cdk5 and Abl Enzyme Substrate 1 (CABLES1) antibodyCABLES1 Reactivity: Human, Mouse WB, ELISA Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- CABLES1 (Cdk5 and Abl Enzyme Substrate 1 (CABLES1))
- Alternative Name
- CABLES1 (CABLES1 Products)
- Synonyms
- CABLES1 antibody, si:dkey-2p18.3 antibody, CABL1 antibody, CABLES antibody, HsT2563 antibody, IK3-1 antibody, Cables antibody, ik3-1 antibody, Cdk5 and Abl enzyme substrate 1 antibody, CDK5 and Abl enzyme substrate 1 antibody, CABLES1 antibody, cables1 antibody, CpipJ_CPIJ019832 antibody, Cables1 antibody
- Background
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Description: Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death (By similarity).
Gene: CABLES1
- Molecular Weight
- 67 kDa
- Gene ID
- 91768
- UniProt
- Q8TDN4
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