Oncostatin M Receptor Protein (OSMR) (AA 28-740) (His tag)
-
- Target See all Oncostatin M Receptor (OSMR) Proteins
- Oncostatin M Receptor (OSMR)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 28-740
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Oncostatin M Receptor protein is labelled with His tag.
- Purpose
- Human OSMR Protein
- Sequence
- Glu28-Met740
- Characteristics
- Recombinant Human OSMR Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu28-Met740.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human OSMR, His Tag at 1μg/ml (100μl/Well) on the plate. Dose response curve for Anti-OSMR Antibody, hFc Tag with the EC50 of 4.4ng/ml determined by ELISA. See testing image for detail.
-
Oncostatin M Receptor (OSMR) (AA 28-737) protein (His tag)
OSMR Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Oncostatin M Receptor (OSMR) (AA 24-737) protein (His tag)OSMR Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Oncostatin M Receptor (OSMR) (AA 1-342) protein (GST tag)OSMR Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Oncostatin M Receptor (OSMR) (AA 141-240) protein (GST tag)OSMR Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Oncostatin M Receptor (OSMR) (AA 762-979) protein (His tag)Crystallography grade OSMR Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Oncostatin M Receptor (OSMR) (AA 759-971) protein (His tag)Crystallography grade OSMR Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Oncostatin M Receptor (OSMR) (AA 28-740) protein (His tag)Crystallography grade OSMR Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Oncostatin M Receptor (OSMR) (AA 24-737) protein (His tag)Crystallography grade OSMR Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Oncostatin M Receptor (OSMR) (AA 28-979) protein (rho-1D4 tag)Crystallography grade OSMR Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Oncostatin M Receptor (OSMR) (AA 24-971) protein (rho-1D4 tag)Crystallography grade OSMR Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
-
- Target
- Oncostatin M Receptor (OSMR)
- Alternative Name
- OSMR (OSMR Products)
- Synonyms
- OSMRB Protein, PLCA1 Protein, oncostatin M receptor Protein, OSMR Protein, Osmr Protein
- Background
- OSMR is targeted to the mitochondrial matrix via the presequence translocase-associated motor complex components, mtHSP70 and TIM44. OSMR interacts with NADH ubiquinone oxidoreductase 1/2 (NDUFS1/2) of complex I and promotes mitochondrial respiration. Deletion of OSMR impairs spare respiratory capacity, increases reactive oxygen species, and sensitizes BTSCs to IR-induced cell death.
- Molecular Weight
- 82.2 kDa. Due to glycosylation, the protein migrates to 110-140 kDa based on Tris-Bis PAGE result.
- Pathways
- JAK-STAT Signaling, Growth Factor Binding
-
