MTDH antibody
(1 reference)-
- Target See all MTDH Antibodies
- MTDH (Metadherin (MTDH))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MTDH antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
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Rabbit polyclonal antibody to LYRIC (metadherin)
LYRIC antibody [N2C3] - Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human LYRIC . The exact sequence is proprietary.
- Isotype
- IgG
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anti-Metadherin (MTDH) (AA 101-270) antibody
MTDH Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Metadherin (MTDH) antibodyMTDH Reactivity: Human WB, IHC, ELISA, FACS Host: Mouse Monoclonal 2F11C3 unconjugated
anti-Metadherin (MTDH) antibodyMTDH Reactivity: Human, Mouse, Rat IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Metadherin (MTDH) (AA 1-582) antibodyMTDH Reactivity: Human WB, IF, IP Host: Rabbit Polyclonal unconjugated
anti-Metadherin (MTDH) (AA 1-582) antibodyMTDH Reactivity: Human WB, IF Host: Mouse Polyclonal unconjugated
anti-Metadherin (MTDH) (AA 101-270) antibodyMTDH Reactivity: Human, Mouse, Rat WB, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
anti-Metadherin (MTDH) (AA 1-260) antibodyMTDH Reactivity: Human IHC, ELISA, IP Host: Rabbit Polyclonal unconjugated
anti-Metadherin (MTDH) (AA 131-230) antibodyMTDH Reactivity: Human WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Metadherin (MTDH) antibodyMTDH Reactivity: Human WB, IHC (p) Host: Mouse Monoclonal CL0397 unconjugated
anti-Metadherin (MTDH) antibodyMTDH Reactivity: Human WB, IHC (p), EIA Host: Mouse Monoclonal 2F11C3 unconjugated
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- Application Notes
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Comment
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Positive Control: rat brain
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.69 mg/mL
- Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Antibodies Against Modified NS1 Wing Domain Peptide Protect Against Dengue Virus Infection." in: Scientific reports, Vol. 7, Issue 1, pp. 6975, (2019) (PubMed).
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: "Antibodies Against Modified NS1 Wing Domain Peptide Protect Against Dengue Virus Infection." in: Scientific reports, Vol. 7, Issue 1, pp. 6975, (2019) (PubMed).
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- Target
- MTDH (Metadherin (MTDH))
- Alternative Name
- metadherin (MTDH Products)
- Synonyms
- MGC75963 antibody, 2610103J23Rik antibody, 3D3 antibody, 3D3/Lyric antibody, AEG-1 antibody, AV353288 antibody, D8Bwg1112e antibody, Lyric antibody, AEG1 antibody, LYRIC antibody, LYRIC/3D3 antibody, metadherin antibody, mtdh antibody, MTDH antibody, Mtdh antibody
- Background
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Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance.
Cellular Localization: Endoplasmic reticulum membrane, Single-pass membrane protein , Nucleus membrane, Single-pass membrane protein (By similarity) , Cell junction , tight junction (By similarity) , Nucleus , nucleolus (By similarity) , Cytoplasm , perinuclear region - Molecular Weight
- 64 kDa
- Gene ID
- 92140
- UniProt
- Q86UE4
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization
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