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GABARAPL2 antibody (N-Term)

GABARAPL2 Reactivity: Human, Mouse, Rat ELISA, WB, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6261855
  • Target See all GABARAPL2 Antibodies
    GABARAPL2 (GABA(A) Receptor-Associated Protein-Like 2 (GABARAPL2))
    Binding Specificity
    • 20
    • 15
    • 12
    • 7
    • 6
    • 6
    • 6
    • 6
    • 2
    • 1
    • 1
    N-Term
    Reactivity
    • 87
    • 23
    • 13
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Human, Mouse, Rat
    Host
    • 88
    • 2
    Rabbit
    Clonality
    • 88
    • 2
    Polyclonal
    Conjugate
    • 26
    • 12
    • 12
    • 11
    • 9
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GABARAPL2 antibody is un-conjugated
    Application
    • 55
    • 52
    • 42
    • 13
    • 13
    • 9
    • 4
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    GABARAPL2 Antibody detects endogenous levels of total GABARAPL2.
    Predicted Reactivity
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human GABARAPL2, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product GABARAPL2 Primary Antibody
  • Application Notes
    WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    GABARAPL2 (GABA(A) Receptor-Associated Protein-Like 2 (GABARAPL2))
    Alternative Name
    GABARAPL2 (GABARAPL2 Products)
    Background

    Description: Ubiquitin-like modifier involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity). Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.

    Gene: GABARAPL2

    Molecular Weight
    14 kDa
    Gene ID
    11345
    UniProt
    P60520
    Pathways
    Autophagy
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