SMARCA5 antibody (C-Term)
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- Target See all SMARCA5 Antibodies
- SMARCA5 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 (SMARCA5))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SMARCA5 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Specificity
- SMARCA5 Antibody detects endogenous levels of total SMARCA5.
- Predicted Reactivity
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human SMARCA5, corresponding to a region within C-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product SMARCA5 Primary Antibody
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anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 (SMARCA5) (AA 59-147) antibody
SMARCA5 Reactivity: Human WB, ELISA, IF, IHC (p) Host: Mouse Monoclonal 3F4 unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 (SMARCA5) (AA 1-1052) antibodySMARCA5 Reactivity: Human WB, IF Host: Mouse Polyclonal unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 (SMARCA5) (AA 100-400) antibodySMARCA5 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 (SMARCA5) (AA 1-1052) antibodySMARCA5 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 (SMARCA5) (AA 946-975), (C-Term) antibodySMARCA5 Reactivity: Human WB, FACS Host: Rabbit Polyclonal RB20627 unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 (SMARCA5) (AA 59-147) antibodySMARCA5 Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 (SMARCA5) antibodySMARCA5 Reactivity: Human, Mouse WB, IF Host: Rabbit Polyclonal unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 (SMARCA5) antibodySMARCA5 Reactivity: Human, Mouse WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 (SMARCA5) (AA 51-100) antibodySMARCA5 Reactivity: Human, Mouse, Rat, Horse, Cow, Dog, Guinea Pig, Rabbit, Bat, Monkey, Pig WB Host: Rabbit Polyclonal unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 (SMARCA5) antibodySMARCA5 Reactivity: Human, Mouse, Rat WB, IF, IP, ChIP, IC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- SMARCA5 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 (SMARCA5))
- Alternative Name
- SMARCA5 (SMARCA5 Products)
- Synonyms
- fb26d12 antibody, fb49g04 antibody, chunp6878 antibody, im:7146484 antibody, wu:fb26d12 antibody, wu:fb49g04 antibody, zgc:158434 antibody, smarca5 antibody, iswi antibody, SMARCA5 antibody, hiswi antibody, snf2h antibody, hsnf2h antibody, wcrf135 antibody, MGC79455 antibody, ISWI antibody, SNF2H antibody, WCRF135 antibody, hISWI antibody, hSNF2H antibody, 4933427E24Rik antibody, D030040M08Rik antibody, D330027N15Rik antibody, MommeD4 antibody, Snf2h antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 S homeolog antibody, smarca5 antibody, smarca5.S antibody, SMARCA5 antibody, Smarca5 antibody
- Background
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Description: Helicase that possesses intrinsic ATP-dependent nucleosome-remodeling activity. Complexes containing SMARCA5 are capable of forming ordered nucleosome arrays on chromatin, this may require intact histone H4 tails. Also required for replication of pericentric heterochromatin in S-phase specifically in conjunction with BAZ1A. Probably plays a role in repression of polI dependent transcription of the rDNA locus, through the recruitment of the SIN3/HDAC1 corepressor complex to the rDNA promoter. Essential component of the WICH complex, a chromatin remodeling complex that mobilizes nucleosomes and reconfigures irregular chromatin to a regular nucleosomal array structure. The WICH complex regulates the transcription of various genes, has a role in RNA polymerase I and RNA polymerase III transcription, mediates the histone H2AX phosphorylation at 'Tyr-142', and is involved in the maintenance of chromatin structures during DNA replication processes. Essential component of the NoRC (nucleolar remodeling complex) complex, a complex that mediates silencing of a fraction of rDNA by recruiting histone-modifying enzymes and DNA methyltransferases, leading to heterochromatin formation and transcriptional silencing.
Gene: SMARCA5
- Molecular Weight
- 122kDa
- Gene ID
- 8467
- UniProt
- O60264
- Pathways
- Chromatin Binding
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