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FOXP2 antibody (C-Term)

Verified FOXP2 Reactivity: Human WB, ELISA Host: Goat Polyclonal unconjugated
Catalog No. ABIN263146
  • Target See all FOXP2 Antibodies
    FOXP2 (Forkhead Box P2 (FOXP2))
    Binding Specificity
    • 11
    • 9
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 46
    • 24
    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 36
    • 7
    • 2
    • 1
    • 1
    Goat
    Clonality
    • 38
    • 8
    • 1
    Polyclonal
    Conjugate
    • 29
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FOXP2 antibody is un-conjugated
    Application
    • 35
    • 28
    • 15
    • 7
    • 6
    • 5
    • 3
    • 3
    Western Blotting (WB), ELISA
    Purpose
    FOXP2 (C terminus)
    Sequence
    REIEEEPLSE DLE
    Specificity
    This antibody is expected to recognise all three reported isoforms (NP_055306.1, NP_683696.2, NP_683697.1).
    Cross-Reactivity
    Cow, Dog, Human, Mouse, Pig, Rat
    Purification
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
    Grade
    Verified
    Immunogen
    Peptide with sequence C-REIEEEPLSEDLE, from the C Terminus of the protein sequence according to NP_055306.1, NP_683696.2, NP_683697.1.
    Isotype
    IgG
  • Application Notes

    Western Blot: Approx 80-90 kDa band observed in Human Brain (Cerebellum) lysates (calculated MW of 82.6 kDa according to NP_683696.2). This molecular weight is routinely observed by other sources. Recommended concentration: 0.5-2 μg/mL. Primary incubation

    Peptide ELISA: antibody detection limit dilution 1:128000.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Minimize freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
  • Willett, Bayin, Lee, Krishnamurthy, Wojcinski, Lao, Stephen, Rosello-Diez, Dauber-Decker, Orvis, Wu, Tessier-Lavigne, Joyner: "Cerebellar nuclei excitatory neurons regulate developmental scaling of presynaptic Purkinje cell number and organ growth." in: eLife, Vol. 8, (2020) (PubMed).

    Plaas, Seppa, Reimets, Jagomäe, Toots, Koppel, Vallisoo, Nigul, Heinla, Meier, Kaasik, Piirsoo, Hickey, Terasmaa, Vasar: "Wfs1- deficient rats develop primary symptoms of Wolfram syndrome: insulin-dependent diabetes, optic nerve atrophy and medullary degeneration." in: Scientific reports, Vol. 7, Issue 1, pp. 10220, (2019) (PubMed).

    Haldipur, Dang, Aldinger, Janson, Guimiot, Adle-Biasette, Dobyns, Siebert, Russo, Millen: "Phenotypic outcomes in Mouse and Human Foxc1 dependent Dandy-Walker cerebellar malformation suggest shared mechanisms." in: eLife, Vol. 6, (2017) (PubMed).

    Fujita, Morita, Furuichi, Sugihara: "Clustered fine compartmentalization of the mouse embryonic cerebellar cortex and its rearrangement into the postnatal striped configuration." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 45, pp. 15688-703, (2012) (PubMed).

    Fujita, Sugihara: "FoxP2 expression in the cerebellum and inferior olive: development of the transverse stripe-shaped expression pattern in the mouse cerebellar cortex." in: The Journal of comparative neurology, Vol. 520, Issue 3, pp. 656-77, (2011) (PubMed).

  • Target
    FOXP2 (Forkhead Box P2 (FOXP2))
    Alternative Name
    FOXP2 (FOXP2 Products)
    Synonyms
    CAGH44 antibody, SPCH1 antibody, TNRC10 antibody, 2810043D05Rik antibody, AI449000 antibody, CAG-16 antibody, D0Kist7 antibody, RGD1559697 antibody, FOXP2 antibody, spch1 antibody, cagh44 antibody, tnrc10 antibody, xlFoxP2 antibody, foxP2 antibody, foxP antibody, Foxp2 antibody, foxP2b antibody, foxp2a antibody, forkhead box P2 antibody, lmw-gs antibody, forkhead box transcription factor antibody, forkhead box P2 L homeolog antibody, FOXP2 antibody, Foxp2 antibody, foxp2 antibody, foxP2 antibody, foxp1c antibody, foxp2.L antibody
    Background
    FOXP2, forkhead box P2, SPCH1, CAGH44, TNRC10, CAG repeat protein 44, speech and language disorder 1, trinucleotide repeat containing 10, forkhead/winged-helix transcription factor, DKFZp686H1726, OTTHUMP00000196932
    Gene ID
    93986
    NCBI Accession
    NP_055306, NP_683696, NP_683697
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