MUC16 antibody (AA 1-200)
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- Target See all MUC16 (CA125) Antibodies
- MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))
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Binding Specificity
- AA 1-200
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This MUC16 antibody is un-conjugated
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Application
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Purification
- purified
- Immunogen
- Purified recombinant fragment of human MUC16 (AA: extra 1-200) expressed in E. coli.
- Clone
- 4C8C8
- Isotype
- IgG1
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anti-Mucin 16, Cell Surface Associated (CA125) (AA 13977-14117) antibody
CA125 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Mucin 16, Cell Surface Associated (CA125) antibodyCA125 Reactivity: Human IHC, StM Host: Rabbit Monoclonal OCA125-2349R unconjugated Recombinant Antibody
anti-Mucin 16, Cell Surface Associated (CA125) (AA 2-258) antibodyCA125 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Mucin 16, Cell Surface Associated (CA125) (AA 14067-14328) antibodyCA125 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Mucin 16, Cell Surface Associated (CA125) (AA 250-350) antibodyCA125 Reactivity: Human ELISA, WB, IHC (p), FACS, IF (p), IF (cc), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Mucin 16, Cell Surface Associated (CA125) antibodyCA125 Reactivity: Human, Mouse, Rat IHC Host: Rabbit Polyclonal unconjugated
anti-Mucin 16, Cell Surface Associated (CA125) antibodyCA125 Reactivity: Human IHC, StM Host: Mouse Monoclonal MUC16-1860 unconjugated
anti-Mucin 16, Cell Surface Associated (CA125) (AA 10329-10628) antibodyCA125 Reactivity: Human WB, IHC, IHC (p) Host: Mouse Monoclonal 2C4 unconjugated
anti-Mucin 16, Cell Surface Associated (CA125) (AA 10329-10628) antibodyCA125 Reactivity: Human WB, IHC, IHC (p) Host: Mouse Monoclonal 3B6 unconjugated
anti-Mucin 16, Cell Surface Associated (CA125) antibodyCA125 Reactivity: Human ELISA, IF Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB:1:500 - 1:2000, IHC:1:200 - 1:1000, FCM:1:200 - 1:400, ELISA:1:10000,
- Restrictions
- For Research Use only
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- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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- Target
- MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))
- Alternative Name
- MUC16 (CA125 Products)
- Synonyms
- CA125 antibody, 1110008I14Rik antibody, Ca125 antibody, Gm1480 antibody, RGD1308422 antibody, MUC16 antibody, mucin 16, cell surface associated antibody, mucin 16 antibody, mucin-16 antibody, MUC16 antibody, Muc16 antibody, LOC476718 antibody, LOC712735 antibody
- Background
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Description: This gene encodes a protein that is a member of the mucin family. Mucins are high molecular weight, O-glycosylated proteins that play an important role in forming a protective mucous barrier, and are found on the apical surfaces of the epithelia. The encoded protein is a membrane-tethered mucin that contains an extracellular domain at its amino terminus, a large tandem repeat domain, and a transmembrane domain with a short cytoplasmic domain. The amino terminus is highly glycosylated, while the repeat region contains 156 amino acid repeats unit that are rich in serines, threonines, and prolines. Interspersed within the repeats are Sea urchin sperm protein Enterokinase and Agrin (SEA) modules, leucine-rich repeats and ankyrin (ANK) repeats. These regions together form the ectodomain, and there is a potential cleavage site found near an SEA module close to the transmembrane domain. This protein is thought to play a role in forming a barrier, protecting epithelial cells from pathogens. Products of this gene have been used as a marker for different cancers, with higher expression levels associated with poorer outcomes.
Aliases: CA125
- Molecular Weight
- 1519 kDa
- Gene ID
- 94025
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