OPN4 antibody (AA 400-480)
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- Target See all OPN4 Antibodies
- OPN4 (Opsin 4 (OPN4))
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Binding Specificity
- AA 400-480
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This OPN4 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- Purpose
- Melanopsin Polyclonal Antibody
- Specificity
- Melanopsin Polyclonal Antibody detects endogenous levels of Melanopsin protein.
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- Immunogen
- Synthesized peptide derived from the C-terminal region of human Melanopsin at AA range: 400-480
- Isotype
- IgG
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anti-Opsin 4 (OPN4) (C-Term) antibody
OPN4 Reactivity: Human WB, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Opsin 4 (OPN4) (C-Term) antibodyOPN4 Reactivity: Human WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Opsin 4 (OPN4) (AA 365-489) antibodyOPN4 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Opsin 4 (OPN4) (AA 429-478) antibodyOPN4 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.
- Comment
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Primary Antibody
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Target
- OPN4 (Opsin 4 (OPN4))
- Alternative Name
- Melanopsin (OPN4 Products)
- Synonyms
- MOP antibody, 1110007J02Rik antibody, Gm533 antibody, OPN4-2 antibody, cOpn4L antibody, melanopsin antibody, opn4-A antibody, Xmop antibody, opn4 antibody, opn4d antibody, opsin 4 antibody, opsin 4 (melanopsin) antibody, melanopsin antibody, melanopsin-B-like L homeolog antibody, opsin 4a (melanopsin) antibody, OPN4 antibody, Opn4 antibody, LOC100303707 antibody, LOC100485437.L antibody, opn4a antibody
- Background
- Rabbit Anti-Melanopsin Polyclonal Antibody,OPN4, MOP, Melanopsin, Opsin-4,Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. OPN4 encodes a photoreceptive opsin protein melanopsin that is expressed within the ganglion and amacrine cell layers of the retina. In mouse, retinal ganglion cell axons expressing this gene projected to the suprachiasmatic nucleus and other brain nuclei involved in circadian photoentrainment. In mouse, this protein is coupled to a transient receptor potential (TRP) ion channel through a G protein signaling pathway and produces a physiologic light response via membrane depolarization and increased intracellular calcium. Melanopsin functions as a sensory photopigment and may also have photoisomerase activity. Experiments with knockout mice indicate that this gene attenuates, but does not abolish, photoentrainment. Alternative splicing results in multiple transcript variants encoding different isoforms.,Melanopsin
- Molecular Weight
- observerd band 55kDa
- Gene ID
- 94233
- UniProt
- Q9UHM6
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