CD33 antibody (AA 15-237)
(2 references)-
- Target See all CD33 Antibodies
- CD33
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Binding Specificity
- AA 15-237
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD33 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Purification
- purified
- Immunogen
- Purified recombinant fragment of human CD33 (AA: 15-237) expressed in E. coli.
- Clone
- 2C6B7
- Isotype
- IgG1
- Top Product
- Discover our top product CD33 Primary Antibody
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anti-CD33 (CD33) (AA 101-200) antibody
CD33 Reactivity: Human, Mouse FACS, WB, ELISA, IHC (fro), IF (p), IF (cc), IHC (p), ICC Host: Rabbit Polyclonal unconjugated
anti-CD33 (CD33) (AA 18-240) antibodyCD33 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-CD33 (CD33) (AA 49-259) antibodyCD33 Reactivity: Human WB, IF, IHC Host: Rabbit Polyclonal unconjugated
anti-CD33 (CD33) (AA 261-364) antibodyCD33 Reactivity: Human FACS, WB, ELISA, IHC (fro), IF (p), IF (cc), IHC (p) Host: Rabbit Polyclonal unconjugated
anti-CD33 (CD33) (AA 1-364) antibodyCD33 Reactivity: Human WB, ELISA, RNAi Host: Mouse Monoclonal 2D12-G4 unconjugated
anti-CD33 (CD33) (AA 18-269) antibodyCD33 Reactivity: Human FACS, ELISA Host: Rabbit Monoclonal DM77 unconjugated
anti-CD33 (CD33) antibodyCD33 Reactivity: Human, Non-Human Primate FACS, WB, IP, IHC (fro), ICC, Func, CyTOF Host: Mouse Monoclonal WM53 unconjugated
anti-CD33 (CD33) antibodyCD33 Reactivity: Human, Non-Human Primate FACS, WB, IP, IHC (fro), ICC, CyTOF Host: Mouse Monoclonal WM53 unconjugated
anti-CD33 (CD33) antibody (Biotin)CD33 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal HIM3-4 Biotin
anti-CD33 (CD33) antibody (FITC)CD33 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal WM53 FITC
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- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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: "The prevalence of CD33 and MS4A6A variant in Chinese Han population with Alzheimer's disease." in: Human genetics, Vol. 131, Issue 7, pp. 1245-9, (2012) (PubMed).
: "A single-chain triplebody with specificity for CD19 and CD33 mediates effective lysis of mixed lineage leukemia cells by dual targeting." in: mAbs, Vol. 3, Issue 1, pp. 21-30, (2011) (PubMed).
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: "The prevalence of CD33 and MS4A6A variant in Chinese Han population with Alzheimer's disease." in: Human genetics, Vol. 131, Issue 7, pp. 1245-9, (2012) (PubMed).
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- Target
- CD33
- Alternative Name
- CD33 (CD33 Products)
- Synonyms
- SIGLEC-3 antibody, SIGLEC3 antibody, p67 antibody, Siglec-3 antibody, gp67 antibody, CD33 molecule antibody, CD33 antigen antibody, CD33 antibody, Cd33 antibody
- Background
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Description: The protein encoded by this gene belongs to putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro) and CD33 plays potential key roles in the pathogenesis of Alzheimer's disease (AD)
Aliases: p67, SIGLEC3, SIGLEC-3
- Molecular Weight
- 39.8 kDa
- Gene ID
- 945
- HGNC
- 945
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