For best experience we recommend to activate Javascript in your browser.

GDF15 antibody (AA 49-308)

Name: GDF15 antibody (AA 49-308)
Brand: antibodies-online
SKU: ABIN3020659
Price: 731.45 USD
Availability: InStock

GDF15 Reactivity: Human WB, IHC, IP, IF Host: Rabbit Polyclonal unconjugated

Western blot analysis of SW620 cell lysate using GDF15 antibody.

Immunofluorescence analysis of BALB-3T3 cells using GDF15 Rabbit pAb (ABIN3020658, ABIN3020659, ABIN3020660, ABIN1512942 and ABIN6213652) at dilution of 1:100 (40x lens).

Western blot analysis of extracts of various cell lines, using GDF15 Antibody.

Expression of GDF15 modulates the expression of epithelial-mesenchymal transition markers in human HT1376 cells.

Immunohistochemistry of paraffin-embedded human placenta using GDF15 Rabbit pAb (ABIN3020658, ABIN3020659, ABIN3020660, ABIN1512942 and ABIN6213652) at dilution of 1:100 (40x lens).

IHC

Immunoprecipitation analysis of 200 μg extracts of HT-1080 cells using 3 μg GDF15 antibody (ABIN3020658, ABIN3020659, ABIN3020660, ABIN1512942 and ABIN6213652).

6 images

(3 references)

Catalog No. ABIN3020659

Datasheet as PDF

Target See all GDF15 Antibodies

GDF15 (Growth Differentiation Factor 15 (GDF15))
Binding Specificity
18

15

11

8

7

5

5

5

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
AA 49-308
Reactivity
88

30

23

1

1
Human
Host
85

12

3

1
Rabbit
Compatible Secondaries
Clonality
85

15

1
Polyclonal
Conjugate
52

15

9

8

3

3

1

1

1

1

1

1

1

1

1

1

1
This GDF15 antibody is un-conjugated
Application
86

54

35

16

13

13

9

6

6

5

3

2

2

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Sequence

EDSRFRELRK RYEDLLTRLR ANQSWEDSNT DLVPAPAVRI LTPEVRLGSG GHLHLRISRA ALPEGLPEAS RLHRALFRLS PTASRSWDVT RPLRRQLSLA RPQAPALHLR LSPPPSQSDQ LLAESSSARP QLELHLRPQA ARGRRRARAR NGDHCPLGPG RCCRLHTVRA SLEDLGWADW VLSPREVQVT MCIGACPSQF RAANMHAQIK TSLHRLKPDT VPAPCCVPAS YNPMVLIQKT DTGVSLQTYD DLLAKDCHCI

Cross-Reactivity

Human, Mouse, Rat

Characteristics

Polyclonal Antibodies

Purification

Affinity purification

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 49-308 of human GDF15 (NP_004855.2).

Isotype

IgG
anti-Growth Differentiation Factor 15 (GDF15) (C-Term) antibody
Verified GDF15 Reactivity: Human WB, ELISA, IHC, FACS Host: Goat Polyclonal unconjugated

anti-Growth Differentiation Factor 15 (GDF15) (C-Term) antibody (Biotin)
GDF15 Reactivity: Human, Mouse WB, ELISA Host: Rabbit Polyclonal Biotin

anti-Growth Differentiation Factor 15 (GDF15) (AA 51-79) antibody
GDF15 Reactivity: Human WB, ELISA, IHC, FACS Host: Rabbit Polyclonal unconjugated

anti-Growth Differentiation Factor 15 (GDF15) (AA 30-308) antibody
GDF15 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Growth Differentiation Factor 15 (GDF15) (AA 221-308) antibody
GDF15 Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-Growth Differentiation Factor 15 (GDF15) (AA 51-79), (N-Term) antibody
GDF15 Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB30209 unconjugated

anti-Growth Differentiation Factor 15 (GDF15) (C-Term) antibody (HRP)
GDF15 Reactivity: Human, Mouse WB, ELISA Host: Rabbit Polyclonal HRP

anti-Growth Differentiation Factor 15 (GDF15) (AA 195-308) antibody
GDF15 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Growth Differentiation Factor 15 (GDF15) (AA 198-308) antibody
GDF15 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated

anti-Growth Differentiation Factor 15 (GDF15) (AA 16-143) antibody
GDF15 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated

Application Notes

WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200,IP,1:50 - 1:200

Restrictions

For Research Use only
Format

Liquid

Buffer

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice

Avoid freeze / thaw cycles

Storage

-20 °C

Storage Comment

Store at -20°C. Avoid freeze / thaw cycles.
Wang, Yang, Dai, Lu, Zhang, Keller: "Prostate cancer promotes a vicious cycle of bone metastasis progression through inducing osteocytes to secrete GDF15 that stimulates prostate cancer growth and invasion." in: Oncogene, Vol. 38, Issue 23, pp. 4540-4559, (2019) (PubMed).

Han, Dai, Yousafzai, Wang, Wang, Zhou, Lu, Xu, Feng, Jin, Wang: "CXXC4 activates apoptosis through up-regulating GDF15 in gastric cancer." in: Oncotarget, Vol. 8, Issue 61, pp. 103557-103567, (2017) (PubMed).

Tsui, Hsu, Chung, Lin, Feng, Lee, Chang, Juang: "Growth differentiation factor-15: a p53- and demethylation-upregulating gene represses cell proliferation, invasion, and tumorigenesis in bladder carcinoma cells." in: Scientific reports, Vol. 5, pp. 12870, (2016) (PubMed).
Target

GDF15 (Growth Differentiation Factor 15 (GDF15))

Alternative Name

GDF15 (GDF15 Products)

Synonyms

GDF15 antibody, GDF-15 antibody, MIC-1 antibody, MIC1 antibody, NAG-1 antibody, PDF antibody, PLAB antibody, PTGFB antibody, SBF antibody, growth differentiation factor 15 antibody, GDF15 antibody, Gdf15 antibody

Background

The protein encoded by this gene belongs to the transforming growth factor-beta (TGF-beta) family. The protein is expressed in a broad range of cell types, acts as a pleiotropic cytokine and is involved in the stress reponse program of cells after cellular injury. Increased protein levels are associated with disease states such as tissue hypoxia, inflammation, acute injury and oxidative stress.,GDF15,GDF-15,MIC-1,MIC1,NAG-1,PDF,PLAB,PTGFB,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cytoskeleton,Extracellular Matrix,Bone,Growth factor,Immunology & Inflammation,Cytokines,Cardiovascular,Heart,Hypertrophy,GDF15

Molecular Weight

34 kDa

Gene ID

9518

UniProt

Q99988

Pathways

SARS-CoV-2 Protein Interactome