FNIP1 antibody
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- Target See all FNIP1 Antibodies
- FNIP1 (Folliculin Interacting Protein 1 (FNIP1))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FNIP1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- Strong expression is found in the heart, liver placenta, muscle, nasal mucosa, salivary gland and uvula and moderate expression in kidney and lung. Higher levels detected in clear cell renal cell carcinoma (RCC) and chromophobe RCC than in normal kidney tissue.,Detects ~130 kDa.
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Peptide Affinity Purified
- Immunogen
- Synthetic peptide from the mid-protein of Human FNIP1
- Isotype
- IgG
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anti-Folliculin Interacting Protein 1 (FNIP1) antibody (HRP)
FNIP1 Reactivity: Human WB, IHC, IF, ICC Host: Rabbit Polyclonal HRP
anti-Folliculin Interacting Protein 1 (FNIP1) antibody (FITC)FNIP1 Reactivity: Human WB, IHC, IF, ICC Host: Rabbit Polyclonal FITC
anti-Folliculin Interacting Protein 1 (FNIP1) antibody (Alkaline Phosphatase (AP))FNIP1 Reactivity: Human WB, IHC, IF, ICC Host: Rabbit Polyclonal Alkaline Phosphatase (AP)
anti-Folliculin Interacting Protein 1 (FNIP1) antibody (Biotin)FNIP1 Reactivity: Human WB, IHC, IF, ICC Host: Rabbit Polyclonal Biotin
anti-Folliculin Interacting Protein 1 (FNIP1) antibody (PE)FNIP1 Reactivity: Human WB, IHC, IF, ICC Host: Rabbit Polyclonal PE
anti-Folliculin Interacting Protein 1 (FNIP1) antibody (PerCP)FNIP1 Reactivity: Human WB, IHC, IF, ICC Host: Rabbit Polyclonal PerCP
anti-Folliculin Interacting Protein 1 (FNIP1) antibody (APC)FNIP1 Reactivity: Human WB, IHC, IF, ICC Host: Rabbit Polyclonal APC
anti-Folliculin Interacting Protein 1 (FNIP1) antibody (Atto 594)FNIP1 Reactivity: Human WB, IHC, IF, ICC Host: Rabbit Polyclonal Atto 594
anti-Folliculin Interacting Protein 1 (FNIP1) antibody (Atto 488)FNIP1 Reactivity: Human WB, IHC, IF, ICC Host: Rabbit Polyclonal Atto 488
anti-Folliculin Interacting Protein 1 (FNIP1) antibody (Atto 390)FNIP1 Reactivity: Human WB, IHC, IF, ICC Host: Rabbit Polyclonal Atto 390
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- Application Notes
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- WB (1:1000)
- ICC/IF (1:100)
- IHC (1:50)
- optimal dilutions for assays should be determined by the user.
- Comment
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A 1:1000 dilution of ABIN5066839 was sufficient for detection of FNIP1 in 15 μg of mouse kidney cell lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- -20°C
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- Target
- FNIP1 (Folliculin Interacting Protein 1 (FNIP1))
- Alternative Name
- FNIP1 (FNIP1 Products)
- Background
- Folliculin-interacting protein 1 (FNIP1) is a co-chaperone of HSP90 (1). It Inhibits the ATPase activity of HSP90AA1 leading to reduction in its chaperone activity. It may be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways and may regulate the phosphorylation of RPS6KB1 (2). FNIP1 is strongly expressed in the heart, liver placenta, muscle, nasal mucosa, salivary gland, and uvula. Elevated levels of FNIP1 have been detected in renal cell carcinoma (RCC) (3).
- Gene ID
- 96459
- NCBI Accession
- NP_001008738
- UniProt
- Q8TF40
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