TGS1 antibody (AA 714-853)
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- Target See all TGS1 Antibodies
- TGS1 (Trimethylguanosine Synthase 1 (TGS1))
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Binding Specificity
- AA 714-853
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TGS1 antibody is un-conjugated
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Application
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- Cross-Reactivity
- Human, Mouse
- Purification
- Antigen Affinity Purified
- Immunogen
- Recombinant Human Trimethylguanosine synthase protein (714-853AA)
- Isotype
- IgG
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anti-Trimethylguanosine Synthase 1 (TGS1) (AA 713-853) antibody
TGS1 Reactivity: Human ELISA, WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Trimethylguanosine Synthase 1 (TGS1) antibodyTGS1 Reactivity: Human, Mouse IHC Host: Rabbit Polyclonal unconjugated
anti-Trimethylguanosine Synthase 1 (TGS1) (AA 1-141) antibodyTGS1 Reactivity: Human ELISA Host: Mouse Monoclonal 3F1 unconjugated
anti-Trimethylguanosine Synthase 1 (TGS1) (AA 432-481) antibodyTGS1 Reactivity: Human, Mouse, Horse, Monkey, Pig WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- TGS1 (Trimethylguanosine Synthase 1 (TGS1))
- Alternative Name
- TGS1 (TGS1 Products)
- Synonyms
- NCOA6IP antibody, PIMT antibody, PIPMT antibody, D4Ertd800e antibody, Ncoa6ip antibody, Pimt antibody, trimethylguanosine synthase 1 antibody, trimethylguanosine synthase 1 L homeolog antibody, TGS1 antibody, Tgs1 antibody, tgs1.L antibody
- Background
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Background: Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m7G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies (CBs). Plays a role in transcriptional regulation.
Aliases: Cap specific guanine N2 methyltransferase antibody, Cap-specific guanine-N2 methyltransferase antibody, CLL associated antigen KW 2 antibody, CLL-associated antigen KW-2 antibody, DKFZp762A163 antibody, FLJ22995 antibody, HCA137 antibody, Hepatocellular carcinoma associated antigen 137 antibody, Hepatocellular carcinoma-associated antigen 137 antibody, NCOA6IP antibody, Nuclear receptor coactivator 6 interacting protein antibody, Nuclear receptor coactivator 6-interacting protein antibody, PIMT antibody, PIPMT antibody, PRIP interacting protein PIPMT antibody, PRIP interacting protein with methyltransferase domain antibody, PRIP interacting protein with methyltransferase motif antibody, PRIP-interacting protein with methyltransferase motif antibody, SEREX defined antibody, TGS 1 antibody, Tgs1 antibody, TGS1_HUMAN antibody, Trimethylguanosine synthase antibody, Trimethylguanosine synthase homolog (S. cerevisiae) antibody, Trimethylguanosine synthase homolog antibody
- UniProt
- Q96RS0
- Pathways
- Mitotic G1-G1/S Phases, Regulation of Lipid Metabolism by PPARalpha, Ribonucleoprotein Complex Subunit Organization
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