FAM65B antibody
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- Target See all FAM65B Antibodies
- FAM65B (Family with Sequence Similarity 65, Member B (FAM65B))
- Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FAM65B antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Specificity
- FAM65B antibody detects endogenous levels of FAM65B.
- Cross-Reactivity
- Human, Mouse (Murine), Rat (Rattus)
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human FAM65B.
- Isotype
- IgG
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anti-Family with Sequence Similarity 65, Member B (FAM65B) (AA 1-591) antibody
FAM65B Reactivity: Human WB, ELISA Host: Mouse Monoclonal 2E6-1B10 unconjugated
anti-Family with Sequence Similarity 65, Member B (FAM65B) (AA 1-210) antibodyFAM65B Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-Family with Sequence Similarity 65, Member B (FAM65B) (AA 829-856), (C-Term) antibodyFAM65B Reactivity: Human WB Host: Rabbit Polyclonal RB37251 unconjugated
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C.Stable for 12 months from date of receipt
- Expiry Date
- 12 months
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- Target
- FAM65B (Family with Sequence Similarity 65, Member B (FAM65B))
- Alternative Name
- FAM65B (FAM65B Products)
- Synonyms
- C6orf32 antibody, DIFF40 antibody, DIFF48 antibody, MYONAP antibody, PL48 antibody, 1700108N18Rik antibody, 6330500D04Rik antibody, AI225904 antibody, E430013J17Rik antibody, si:dkey-218n20.1 antibody, Ab2-162 antibody, RGD1306939 antibody, RHO family interacting cell polarization regulator 2 antibody, family with sequence similarity 65, member B antibody, ripor2 antibody, RIPOR2 antibody, Ripor2 antibody, FAM65B antibody
- Background
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Description: Acts as an inhibitor of the small GTPase RHOA and plays several roles in the regulation of myoblast and hair cell differentiation, lymphocyte T proliferation and neutrophil polarization (PubMed:17150207, PubMed:24687993, PubMed:23241886, PubMed:24958875, PubMed:25588844, PubMed:27556504). Inhibits chemokine-induced T lymphocyte responses, such as cell adhesion, polarization and migration (PubMed:23241886). Involved also in the regulation of neutrophil polarization, chemotaxis and adhesion (By similarity). Required for normal development of inner and outer hair cell stereocilia within the cochlea of the inner ear (By similarity). Plays a role for maintaining the structural organization of the basal domain of stereocilia (By similarity). Involved in mechanosensory hair cell function (By similarity). Required for normal hearing (PubMed:24958875).
Gene: RIPOR2
- Molecular Weight
- 115 kDa,66 kDa
- Gene ID
- 9750
- UniProt
- Q9Y4F9
- Pathways
- Transition Metal Ion Homeostasis
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