IST1 antibody (AA 172-284)
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- Target See all IST1 Antibodies
- IST1 (Increased Sodium Tolerance 1 Homolog (IST1))
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Binding Specificity
- AA 172-284
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IST1 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human IST1 homolog protein (172-284AA)
- Isotype
- IgG
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anti-Increased Sodium Tolerance 1 Homolog (IST1) antibody
IST1 Reactivity: Human, Mouse, Rat ELISA, WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Increased Sodium Tolerance 1 Homolog (IST1) (AA 125-317) antibodyIST1 Reactivity: Human WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Increased Sodium Tolerance 1 Homolog (IST1) antibodyIST1 Reactivity: Human ELISA, WB Host: Mouse Monoclonal 22 unconjugated
anti-Increased Sodium Tolerance 1 Homolog (IST1) (N-Term) antibodyIST1 Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio), Pig, Monkey, Bat, Xenopus laevis, Chicken WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- IST1 (Increased Sodium Tolerance 1 Homolog (IST1))
- Alternative Name
- IST1 (IST1 Products)
- Synonyms
- 2400003C14Rik antibody, AW536298 antibody, mKIAA0174 antibody, RGD1307799 antibody, OLC1 antibody, fb16b04 antibody, wu:fb16b04 antibody, wu:fi89e07 antibody, zgc:55671 antibody, ist1 antibody, kiaa0174 antibody, pm28 antibody, increased sodium tolerance 1 homolog (yeast) antibody, IST1, ESCRT-III associated factor antibody, increased sodium tolerance 1 homolog S homeolog antibody, Ist1 antibody, IST1 antibody, ist1 antibody, ist1.S antibody
- Background
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Background: ESCRT-III-like protein involved in specific functions of the ESCRT machinery. Is required for efficient abscission during cytokinesis, but not for HIV-1 budding. The involvement in the MVB pathway is not established. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells (PubMed:19129479, PubMed:19129480). During late anaphase, involved in nuclear envelope reassembly and mitotic spindle disassembly together with the ESCRT-III complex: IST1 acts by mediating the recruitment of SPAST to the nuclear membrane, leading to microtubule severing (PubMed:26040712). Regulates early endosomal tubulation together with the ESCRT-III complex by mediating the recruitment of SPAST (PubMed:23897888).
Aliases: hIST1 antibody, Increased sodium tolerance 1 antibody, Increased sodium tolerance 1 homolog antibody, IST1 homolog antibody, IST1_HUMAN antibody, KIAA0174 antibody, MAPK activating protein PM28 antibody, MGC117220 antibody, MGC128433 antibody, Putative MAPK-activating protein PM28 antibody
- UniProt
- P53990
- Pathways
- Regulation of Cell Size
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