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CDC27 antibody (AA 551-830)

CDC27 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1679113
  • Target See all CDC27 Antibodies
    CDC27 (Cell Division Cycle 27 Homolog (S. Cerevisiae) (CDC27))
    Binding Specificity
    • 17
    • 15
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 551-830
    Reactivity
    • 62
    • 45
    • 28
    • 9
    • 7
    • 6
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 72
    • 6
    Rabbit
    Clonality
    • 64
    • 14
    Polyclonal
    Conjugate
    • 32
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    This CDC27 antibody is un-conjugated
    Application
    • 27
    • 27
    • 27
    • 22
    • 11
    • 11
    • 7
    • 7
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Sequence
    HLQKDVALSV LSKDLTDMDK NSPEAWCAAG NCFSLQREHD IAIKFFQRAI QVDPNYAYAY TLLGHEFVLT EELDKALACF RNAIRVNPRH YNAWYGLGMI YYKQEKFSLA EMHFQKALDI NPQSSVLLCH IGVVQHALKK SEKALDTLNK AIVIDPKNPL CKFHRASVLF ANEKYKSALQ ELEELKQIVP KESLVYFLIG KVYKKLGQTH LALMNFSWAM DLDPKGANNQ IKEAIDKRYL PDDEEPITQE EQIMGTDESQ ESSMTDADDT QLHAAESDEF
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 551-830 of human CDC27 (NP_001107563.1).
    Isotype
    IgG
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    CDC27 (Cell Division Cycle 27 Homolog (S. Cerevisiae) (CDC27))
    Alternative Name
    CDC27 (CDC27 Products)
    Synonyms
    ANAPC3 antibody, APC3 antibody, CDC27Hs antibody, D0S1430E antibody, D17S978E antibody, HNUC antibody, NUC2 antibody, wu:fb54g06 antibody, wu:fc88c12 antibody, AI452358 antibody, BC023187 antibody, CDC27 antibody, NV10210 antibody, cell division cycle 27 antibody, cell division cycle 27 S homeolog antibody, cell division cycle protein 27 homolog antibody, anaphase-promoting complex subunit Apc3 antibody, CDC27 antibody, cdc27 antibody, Cdc27 antibody, cdc27.S antibody, LOC100123129 antibody, nuc2 antibody
    Background
    The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of the anaphase-promoting complex (APC), which is composed of eight protein subunits and is highly conserved in eukaryotic cells. This complex catalyzes the formation of cyclin B-ubiquitin conjugate, which is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. The protein encoded by this gene and three other members of the APC complex contain tetratricopeptide (TPR) repeats, which are important for protein-protein interactions. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and it may thus be involved in controlling the timing of mitosis. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2, 22 and Y.,CDC27,ANAPC3,APC3,CDC27Hs,D0S1430E,D17S978E,H-NUC,HNUC,NUC2,Cell Biology & Developmental Biology,Cell Cycle,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,CDC27
    Molecular Weight
    91 kDa/92 kDa
    Gene ID
    996
    UniProt
    P30260
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