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Browse our EIF2AK2 (EIF2AK2) ELISA Kits

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Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 ELISA Kits (EIF2AK2)
On www.antibodies-online.com are 16 Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2) ELISA Kits from 8 different suppliers available. Additionally we are shipping EIF2AK2 Antibodies (266) and EIF2AK2 Proteins (6) and many more products for this protein. A total of 307 EIF2AK2 products are currently listed.
Synonyms:
2310047A08Rik, 4732414G15Rik, AI467567, AI747578, DKFZp469K1934, EIF2AK1, EIF2AK2, Pkr, Prkr, Tik
list all ELISA KIts Gene Name GeneID UniProt
EIF2AK2 5610 P19525
EIF2AK2 19106 Q03963
EIF2AK2 54287 Q63184

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EIF2AK2 (EIF2AK2) ELISA Kits by Reactivity

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Human Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2) interaction partners

  1. It was established in this report that interactions between PACT (show RBBP6 ELISA Kits), ADAR1 (show ADAR ELISA Kits) and HIV-1-encoded Tat (show TAT ELISA Kits) protein diminish the activation of PKR (show PKLR ELISA Kits) in response to HIV-1 infection.

  2. In insulitic islets from living patients with recent-onset T1D, most of the overexpressed ISGs, including GBP1 (show GBP1 ELISA Kits), TLR3 (show TLR3 ELISA Kits), OAS1 (show OAS1 ELISA Kits), EIF2AK2, HLA-E (show HLAE ELISA Kits), IFI6 (show IFI6 ELISA Kits), and STAT1 (show STAT1 ELISA Kits), showed higher expression in the islet core compared with the peri (show PLIN1 ELISA Kits)-islet area containing the surrounding immune cells

  3. NF90 (show MMP4 ELISA Kits) exerts its antiviral activity by antagonizing the inhibitory role of NS1 (show PTPN11 ELISA Kits) on PKR (show PKLR ELISA Kits) phosphorylation

  4. Crucially, Chlamydia trachomatis infection resulted in robust IRE1alpha (show ERN1 ELISA Kits) RNAse activity that was dependent on TLR4 (show TLR4 ELISA Kits) signalling and inhibition of IRE1alpha (show ERN1 ELISA Kits) RNAse activity prevented PKR (show PKLR ELISA Kits) activation.

  5. the expression of a Tat (show TAT ELISA Kits) construct containing mutations in the basic region (49-57aa), which is responsible for the interaction with PKR (show PKLR ELISA Kits), favored neither parasite growth nor IL-10 (show IL10 ELISA Kits) expression in infected macrophages.

  6. This study provides insight into the molecular pathology of Cornelia de Lange syndrome by establishing a relationship between NIPBL (show NIPBL ELISA Kits) and HDAC8 (show HDAC8 ELISA Kits) mutations and PKR (show PKLR ELISA Kits) activation.

  7. The Newcastle disease virus-induced translation shutoff at late infection times was attributed to sustaining phosphorylation of eIF2a (show EIF2S1 ELISA Kits), which is mediated by continual activation of PKR (show PKLR ELISA Kits) and degradation of PP1 (show PPA1 ELISA Kits).

  8. The sole essential function of cytomegalovirus TRS1 is to antagonize host PKR (show PKLR ELISA Kits).

  9. results show that ceramide acts at two distinct levels of the insulin (show INS ELISA Kits) signaling pathway (IRS1 (show IRS1 ELISA Kits) and Akt (show AKT1 ELISA Kits)). PKR (show PKLR ELISA Kits), which is induced by both inflammation signals and ceramide, could play a major role in the development of insulin (show INS ELISA Kits) resistance in muscle cells.

  10. Classical swine fever virus (CSFV) infection increased the phosphorylation of eukaryotic translation initiation factor (show EIF2A ELISA Kits) (eIF)2alpha (show EIF2S1 ELISA Kits) and its kinase PKR (show PKLR ELISA Kits). The activation of PKR (show PKLR ELISA Kits) during CSFV infection is beneficial to the virus.

Mouse (Murine) Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2) interaction partners

  1. We therefore concluded that in osteoblasts, P. gingivalis activated PKR, which in turn increased NLRP3 (show NLRP3 ELISA Kits) expression by activating NF-kappaB (show NFKB1 ELISA Kits). Our results suggest that PKR modulates inflammation by regulating the expression of the NLRP3 (show NLRP3 ELISA Kits) inflammasome through the NF-kappaB (show NFKB1 ELISA Kits) pathway in periodontal diseases.

  2. identify iNOS (show NOS2 ELISA Kits)/NO as an integral component of IFN-beta (show IFNB1 ELISA Kits) production in response to dsRNA in hepatocytes in a pathway that involves the coordinated activities of TLR3 (show TLR3 ELISA Kits)/Trif (show RNF138 ELISA Kits) and PKR

  3. The data predicts that PKR diminishes inflammasome activity by controlling protein translation to repress the induction of factors that are critical for the activity of the cryopyrin (show NLRP3 ELISA Kits) inflammasome.

  4. This study provides insight into the molecular pathology of Cornelia de Lange syndrome by establishing a relationship between NIPBL (show NIPBL ELISA Kits) and HDAC8 (show HDAC8 ELISA Kits) mutations and PKR activation.

  5. Deletion of PKR does not affect HFD-induced obesity, hepatic steatosis or glucose metabolism, and only modestly affects adipose tissue inflammation.

  6. results show that ceramide acts at two distinct levels of the insulin (show INS ELISA Kits) signaling pathway (IRS1 (show IRS1 ELISA Kits) and Akt (show AKT1 ELISA Kits)). PKR, which is induced by both inflammation signals and ceramide, could play a major role in the development of insulin (show INS ELISA Kits) resistance in muscle cells.

  7. Data (including data from studies in transgenic/knockout mice) suggest that PACT/RAX (protein activator of protein kinase (show CDK7 ELISA Kits) R) functions as negative regulator of PKR/Eif2ak2 (protein kinase (show CDK7 ELISA Kits) R) in development of postnatal anterior pituitary tissue.

  8. Data indicate increasing expression of PKR during TNF-a (show TNF ELISA Kits)-induced osteoclast formation. Its inhibition prevents TNF-a (show TNF ELISA Kits)-induced bone destruction in vivo and can be then considered as new therapeutic target for bone disease.

  9. The authors show that Murine cytomegalovirus m142 and m143 knockout mutants attain organ titers equivalent to those attained by wild-type virus in Pkr knockout mice.

  10. these data indicate a pivotal role for PKR's protein-binding function on the proliferation of pancreatic beta cells through TRAF2 (show TRAF2 ELISA Kits)/RIP1 (show RALBP1 ELISA Kits)/NF-kappaB (show NFKB1 ELISA Kits)/c-Myc (show MYC ELISA Kits) pathways.

EIF2AK2 Antigen Profile

Antigen Summary

The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.

Alternative names and synonyms associated with EIF2AK2

  • eukaryotic translation initiation factor 2-alpha kinase 2 (EIF2AK2) Elisa Kit
  • eukaryotic translation initiation factor 2-alpha kinase 2 (eif2ak2) Elisa Kit
  • eukaryotic translation initiation factor 2-alpha kinase 2 (Eif2ak2) Elisa Kit
  • 2310047A08Rik Elisa Kit
  • 4732414G15Rik Elisa Kit
  • AI467567 Elisa Kit
  • AI747578 Elisa Kit
  • DKFZp469K1934 Elisa Kit
  • EIF2AK1 Elisa Kit
  • EIF2AK2 Elisa Kit
  • Pkr Elisa Kit
  • Prkr Elisa Kit
  • Tik Elisa Kit

Protein level used designations for EIF2AK2

double-stranded RNA-activated protein kinase , interferon-induced, double-stranded RNA-activated protein kinase , p68 kinase , P1/eIF-2A protein kinase , interferon-inducible RNA-dependent protein kinase , IFN-stimulated dsRNA-activated eIF2-alpha kinase 2 , double-stranded RNA activated protein kinase , eukaryotic translation initiation factor 2-alpha kinase 2 , double stranded RNA activated protein kinase , eIF-2A protein kinase 2 , interferon-inducible elF2alpha kinase , protein kinase, interferon-inducible double stranded RNA dependent , tyrosine-protein kinase EIF2AK2 , IFN- type I-induced and dsRNA-activated kinase , IFN-induced and double-stranded RNA-activated kinase , T-cell viral integration site , dsRNA-activated kinase , eIF-2 alpha , eukaryotic translation initiation factor 2 alpha kinase 2 , protein kinase RNA-activated , protein kinase, interferon inducible double stranded RNA dependent , serine/threonine-protein kinase TIK , Protein kinase, interferon-inducible double stranded RNA dependent

GENE ID SPECIES
395147 Gallus gallus
459155 Pan troglodytes
611397 Canis lupus familiaris
708912 Macaca mulatta
100001092 Danio rerio
100009013 Oryctolagus cuniculus
100147679 Equus caballus
100173054 Pongo abelii
100579484 Nomascus leucogenys
5610 Homo sapiens
19106 Mus musculus
54287 Rattus norvegicus
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