Browse our MBTPS1 (MBTPS1) ELISA Kits

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Membrane-Bound Transcription Factor Peptidase, Site 1 ELISA Kits (MBTPS1)
On are 0 Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1) ELISA Kits from different suppliers available. Additionally we are shipping MBTPS1 Antibodies (10) and MBTPS1 Proteins (6) and many more products for this protein. A total of 17 MBTPS1 products are currently listed.
0610038M03Rik, AV003995, mKIAA0091, PCSK8, S1p, Ski-1, Ski1
list all ELISA KIts Gene Name GeneID UniProt
Human MBTPS1 MBTPS1 8720 Q14703
Mouse MBTPS1 MBTPS1 56453 Q9WTZ2
Rat MBTPS1 MBTPS1 89842 Q9WTZ3

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More ELISA Kits for MBTPS1 Interaction Partners

Human Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1) interaction partners

  1. Results suggest that (pro)renin receptor (show ATP6AP2 ELISA Kits) (s(P)RR (show ATP6AP2 ELISA Kits)) is generated by sequential processing by site-1 protease (S1P) and furin (show FURIN ELISA Kits) protein.

  2. primordial SKI-1/S1P likely contained a simpler prodomain consisting of the highly conserved AB fragment that represents an independent folding unit

  3. S1P substrate-dependent regulatory mechanisms for lipid synthesis and biogenesis of lysosomes are different

  4. The interaction between S1P and C5a plays an important role in neutrophils for antineutrophil cytoplasmic antibody -mediated activation

  5. Incompletely matured forms of SKI-1/S1P further process cellular and viral substrates in distinct subcellular compartments.

  6. We show that SKI-1 is constitutively expressed in human pigment cells with higher SKI (show SKI ELISA Kits) activity in seven out of eight melanoma cell lines compared with normal melanocytes.

  7. Diabetic high-density lipoprotein carries higher levels of S1P compared with normal high-density lipoprotein.

  8. Y285 of SKI-1 is crucial for the efficient processing of envelope glycoproteins from Old World and clade C New World arenavirus.

  9. The role of MBTPS1 (SKI-1/S1P) peptides in cancer and approaches used to inhibit SKI-1/S1P were studied.

  10. study found that the N-acetylglucosamine-1-phosphotransferase alpha/beta-subunit (show POLG ELISA Kits) precursor is cleaved by S1P that activates sterol regulatory element-binding proteins in response to cholesterol deprivation; S1P functions in the biogenesis of lysosomes

Mouse (Murine) Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1) interaction partners

  1. Data (including data from studies in knockout mice) suggest osteocyte Mbtps1 expression is involved in development of sarcopenia in slow-twitch muscle fibers; Mbtps1 knockout mice (conditional osteocyte deletion) do not develop sarcopenia of aging.

  2. S1P (show S1PR1 ELISA Kits) substrate-dependent regulatory mechanisms for lipid synthesis and biogenesis of lysosomes are different

  3. A novel role for MBTPS1/SKI-1/S1P (membrane bound transcription factor protease, subtilisin kexin isozyme-1, or site 1 protease) in somite segmentation and in the pathogenesis of vertebral anomalies.

  4. These studies indicate an indispensable role for S1P in type IIB procollagen trafficking from the ER.

  5. Site-1 protease is essential to growth plate maintenance and is a critical regulator of chondrocyte hypertrophic differentiation in postnatal mice.

  6. Hypomorphic mutation in the site-1 protease Mbtps1 endows resistance to persistent viral infection in a cell-specific manner

  7. the differentiated phenotype of osteoblastic cells and possibly osteocytes depends upon the non-apoptotic actions of SKI-1.

  8. S1P (show S1PR1 ELISA Kits) affects and sustains all key cellular processes responsible for wound repair and point to a unique potential for this molecule in the therapy of diabetic wounds, particularly as an angiogenic agent in treatment of diabetic wounds.

  9. Site-1 protease is essential for endochondral bone formation.

  10. SKI-1 plays a direct or indirect role in assembly of functional nucleation complexes containing BAG-75 and BSP (show KLK6 ELISA Kits) and their fragments, thus facilitating initial mineral nucleation within these biomineralization foci.

MBTPS1 Antigen Profile

Antigen Summary

The encoded protein has a central role in the regulation of lipid metabolism in cells. It is a sterol-regulated subtilisin-like serine protease that cleaves ER membrane-bound sterol regulatory element-binding proteins (SREBPs), a reaction that initiates the two-step proteolytic process by which transcriptionally active fragments of SREBPs are released from the membrane for translocation to the nucleus. The gene product is an integral membrane ER protein, with the bulk located in the ER lumen. It is synthesized as an inactive preproprotein that is self-activated by an intramolecular cleavage that generates the mature protein.

Alternative names and synonyms associated with MBTPS1

  • membrane-bound transcription factor peptidase, site 1 (MBTPS1) Elisa Kit
  • membrane-bound transcription factor peptidase, site 1 (Mbtps1) Elisa Kit
  • 0610038M03Rik Elisa Kit
  • AV003995 Elisa Kit
  • mKIAA0091 Elisa Kit
  • PCSK8 Elisa Kit
  • S1p Elisa Kit
  • Ski-1 Elisa Kit
  • Ski1 Elisa Kit

Protein level used designations for MBTPS1

endopeptidase S1P , membrane-bound transcription factor site-1 protease , site-1 protease , subtilisin/kexin isozyme-1 , S1P endopeptidase , membrane-bound transcription factor protease, site 1 , sterol-regulated luminal protease , subtilisin/kexin isozyme 1 , subtilisin/kexin isozyme SKI-1

8720 Homo sapiens
56453 Mus musculus
89842 Rattus norvegicus
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