You are viewing an incomplete version of our website. Please click to reload the website as full version.

Browse our anti-Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A) Antibodies

Full name:
anti-Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A Antibodies (PPP1R15A)
On www.antibodies-online.com are 69 Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A) Antibodies from 18 different suppliers available. Additionally we are shipping Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A Proteins (7) and Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A Kits (2) and many more products for this protein. A total of 82 Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A products are currently listed.
Synonyms:
9630030H21, GADD34, Myd116, Peg-3, RGD1624209
list all antibodies Gene Name GeneID UniProt
PPP1R15A 17872 P17564
PPP1R15A 23645 O75807
PPP1R15A 171071 Q6IN02

Show all species

Show all synonyms

Most Popular Reactivities for anti-Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A) Antibodies

Select your species and application

anti-Mouse (Murine) Antibodies:

anti-Human Antibodies:

anti-Rat (Rattus) Antibodies:

All available anti-Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A Antibodies

Go to our pre-filtered search.

Top referenced anti-Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A Antibodies

  1. Human Polyclonal PPP1R15A Primary Antibody for ELISA, IHC - ABIN262735 : Kojima, Takeuchi, Haneda, Yagi, Hasegawa, Yamaki, Takeda, Akira, Shimokata, Isobe: The function of GADD34 is a recovery from a shutoff of protein synthesis induced by ER stress: elucidation by GADD34-deficient mice. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003 (PubMed)
    Show all 2 references for ABIN262735

  2. Human Polyclonal PPP1R15A Primary Antibody for IHC (p), WB - ABIN374070 : Panaretakis, Kepp, Brockmeier, Tesniere, Bjorklund, Chapman, Durchschlag, Joza, Pierron, van Endert, Yuan, Zitvogel, Madeo, Williams, Kroemer: Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell death. in The EMBO journal 2009 (PubMed)

More Antibodies against Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A Interaction Partners

Mouse (Murine) Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A) interaction partners

  1. Sustained protein synthesis sensitized cells to pharmacological induction of the Unfolded Protein Response (UPR), and the observed decrease in cell viability was restored upon inhibition of GADD34 activity. We conclude that NMP4 (show ZNF384 Antibodies) is a key regulator of ribosome biogenesis and the UPR, which together play a central role in determining cell viability during endoplasmic reticulum stress.

  2. Through aging or a high fat diet, insulin (show INS Antibodies) signaling in GADD34-deficient liver converted to be down regulated compared with WT mice.

  3. Results show that GADD34 plays a vital role in promoting cell death following proteasome inhibition via enhancing protein synthesis involved in endoplasmic reticulum stress, reactive oxygen species production and autophagy formation.

  4. avidity for the substrate plays an important role in imparting specificity on the PPP1R15B-PP1G-actin ternary complex.

  5. GADD34 enhances autophagy and suppresses apoptosis stimulated by LPS (show TLR4 Antibodies) combined with amino acid deprivation through regulation of mTOR (show FRAP1 Antibodies) signaling pathway in macrophages.

  6. GADD34 upregulated pro-inflammatory mediator.

  7. GADD34 promotes cell survival and adaptation to increased extracellular osmolarity by increasing the uptake of small neutral amino acids via the amino acid transporter SNAT2 (show SLC38A2 Antibodies).

  8. GADD34 expression was upregulated in the liver of mice after exposure to a carcinogen, diethylnitrosamine (DEN). In both acute and chronic DEN treatment models, GADD34 deficiency not only decreased oncogene (show RAB1A Antibodies) expression, but also reduced hepatic damage.

  9. Thus these results indicate that GADD34 appears to suppress myofibroblast differentiation through inhibiting Smad3 (show SMAD3 Antibodies)-dependent TGFbeta (show TGFB1 Antibodies) signal pathway and promote its apoptosis by activating caspase-3 (show CASP3 Antibodies) pathway

  10. GADD34 works to inhibit the proliferation and differentiation of HSCs or myeloid precursor cells and maintains homeostatic differentiation of neutrophil-lineage cells to avoid early immunological senescence.

Human Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A) interaction partners

  1. reduction of GADD34 expression significantly suppressed tumor, and resulted in decreased accumulation of MDSCs and T-cells, and inhibition of GADD34 reduced secretion of vascular epithelial growth factor alpha and transforming growth factor beta by MDSCs

  2. ANXA11 (show ANXA11 Antibodies) rs1049550 and PPP1R15A rs557806 may improve the identification of mCRC patients sensitive to bevacizumab regimens, and further validation is required in large cohorts

  3. Data of this study strengthen the evidence of an unfolded protein response during the course of RA and provide an insight of the potential interest in GADD34 as a relevant marker for RA.

  4. The results suggest that dephosphorylation of eIF2a (show EIF2S1 Antibodies) by GADD34 plays an important role in doxorubicin resistance of MCF-7/ADR (show AKR1B1 Antibodies) cells.

  5. The reactive oxygen species-generating NADPH oxidase-4 (Nox4 (show NOX4 Antibodies)) is induced downstream of ATF4 (show ATF4 Antibodies), binds to a PP1 (show PPA1 Antibodies)-targeting subunit GADD34 at the endoplasmic reticulum, and inhibits PP1 (show PPA1 Antibodies) activity to increase eIF2alpha (show EIF2A Antibodies) phosphorylation and ATF4 (show ATF4 Antibodies) levels.

  6. stress pathways lead to the induction of the protein GADD34, which appears to provide protection against the toxic effects of the secreted virulence factors in Pseudomonas aeruginosa infection

  7. The data highlight independent interactions of PP1 (show PPA1 Antibodies) and eIF2alpha (show EIF2A Antibodies) with GADD34, demonstrating that GADD34 functions as a scaffold both in vitro and in cells

  8. GADD34 may play a neuroprotective role against amyloid-beta toxicity.

  9. GADD34 enhances autophagy and suppresses apoptosis stimulated by LPS (show IRF6 Antibodies) combined with amino acid deprivation through regulation of mTOR (show FRAP1 Antibodies) signaling pathway in macrophages.

  10. Data indicate that protein phosphatase 1 (show PPP1CB Antibodies) subunit GADD34 directly interacts with eukaryotic translation initiation factor 2 subunit alpha (eIF2alpha (show EIF2S1 Antibodies)).

Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A) Antigen Profile

Antigen Summary

This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation.

Alternative names and synonyms associated with Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A)

  • protein phosphatase 1, regulatory subunit 15A (PPP1R15A) antibody
  • protein phosphatase 1, regulatory (inhibitor) subunit 15A (PPP1R15A) antibody
  • protein phosphatase 1, regulatory (inhibitor) subunit 15A (Ppp1r15a) antibody
  • protein phosphatase 1, regulatory subunit 15A (Ppp1r15a) antibody
  • 9630030H21 antibody
  • GADD34 antibody
  • Myd116 antibody
  • Peg-3 antibody
  • RGD1624209 antibody

Protein level used designations for PPP1R15A

protein phosphatase 1, regulatory (inhibitor) subunit 15A , growth arrest and DNA damage-inducible protein GADD34 , growth arrest and DNA-damage-inducible 34 , myeloid differentiation primary response gene 116 , myeloid differentiation primary response protein MyD116 , protein phosphatase 1 regulatory subunit 15A , myeloid differentiation primary response protein MyD116 homolog , progression elevated gene 3 protein

GENE ID SPECIES
456191 Pan troglodytes
718350 Macaca mulatta
100449481 Pongo abelii
100591446 Nomascus leucogenys
17872 Mus musculus
23645 Homo sapiens
171071 Rattus norvegicus
514688 Bos taurus
476419 Canis lupus familiaris
Selected quality suppliers for anti-Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A) Antibodies
Did you look for something else?