You are viewing an incomplete version of our website. Please click to reload the website as full version.

Browse our Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A) ELISA Kits

Full name:
Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A ELISA Kits (PPP1R15A)
On www.antibodies-online.com are 2 Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A) ELISA Kits from 1 different suppliers available. Additionally we are shipping Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A Antibodies (69) and Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A Proteins (7) and many more products for this protein. A total of 82 Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A products are currently listed.
Synonyms:
9630030H21, GADD34, Myd116, Peg-3, RGD1624209
list all ELISA KIts Gene Name GeneID UniProt
PPP1R15A 17872 P17564
Human PPP1R15A PPP1R15A 23645 O75807
PPP1R15A 171071 Q6IN02

Show all species

Show all synonyms

Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A) ELISA Kits by Reactivity

Select your species

More ELISA Kits for Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A Interaction Partners

Mouse (Murine) Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A) interaction partners

  1. Sustained protein synthesis sensitized cells to pharmacological induction of the Unfolded Protein Response (UPR), and the observed decrease in cell viability was restored upon inhibition of GADD34 activity. We conclude that NMP4 (show ZNF384 ELISA Kits) is a key regulator of ribosome biogenesis and the UPR, which together play a central role in determining cell viability during endoplasmic reticulum stress.

  2. Through aging or a high fat diet, insulin (show INS ELISA Kits) signaling in GADD34-deficient liver converted to be down regulated compared with WT mice.

  3. Results show that GADD34 plays a vital role in promoting cell death following proteasome inhibition via enhancing protein synthesis involved in endoplasmic reticulum stress, reactive oxygen species production and autophagy formation.

  4. avidity for the substrate plays an important role in imparting specificity on the PPP1R15B-PP1G-actin ternary complex.

  5. GADD34 enhances autophagy and suppresses apoptosis stimulated by LPS (show TLR4 ELISA Kits) combined with amino acid deprivation through regulation of mTOR (show FRAP1 ELISA Kits) signaling pathway in macrophages.

  6. GADD34 upregulated pro-inflammatory mediator.

  7. GADD34 promotes cell survival and adaptation to increased extracellular osmolarity by increasing the uptake of small neutral amino acids via the amino acid transporter (show SLC38A7 ELISA Kits) SNAT2 (show SLC38A2 ELISA Kits).

  8. GADD34 expression was upregulated in the liver of mice after exposure to a carcinogen, diethylnitrosamine (DEN). In both acute and chronic DEN treatment models, GADD34 deficiency not only decreased oncogene (show RAB1A ELISA Kits) expression, but also reduced hepatic damage.

  9. Thus these results indicate that GADD34 appears to suppress myofibroblast differentiation through inhibiting Smad3 (show SMAD3 ELISA Kits)-dependent TGFbeta (show TGFB1 ELISA Kits) signal pathway and promote its apoptosis by activating caspase-3 (show CASP3 ELISA Kits) pathway

  10. GADD34 works to inhibit the proliferation and differentiation of HSCs or myeloid precursor cells and maintains homeostatic differentiation of neutrophil-lineage cells to avoid early immunological senescence.

Human Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A) interaction partners

  1. reduction of GADD34 expression significantly suppressed tumor, and resulted in decreased accumulation of MDSCs and T-cells, and inhibition of GADD34 reduced secretion of vascular epithelial growth factor alpha and transforming growth factor beta by MDSCs

  2. ANXA11 (show ANXA11 ELISA Kits) rs1049550 and PPP1R15A rs557806 may improve the identification of mCRC patients sensitive to bevacizumab regimens, and further validation is required in large cohorts

  3. Data of this study strengthen the evidence of an unfolded protein response during the course of RA and provide an insight of the potential interest in GADD34 as a relevant marker for RA.

  4. The results suggest that dephosphorylation of eIF2a (show EIF2S1 ELISA Kits) by GADD34 plays an important role in doxorubicin resistance of MCF-7/ADR (show AKR1B1 ELISA Kits) cells.

  5. The reactive oxygen species-generating NADPH oxidase-4 (Nox4 (show NOX4 ELISA Kits)) is induced downstream of ATF4 (show ATF4 ELISA Kits), binds to a PP1 (show PPA1 ELISA Kits)-targeting subunit GADD34 at the endoplasmic reticulum, and inhibits PP1 (show PPA1 ELISA Kits) activity to increase eIF2alpha (show EIF2A ELISA Kits) phosphorylation and ATF4 (show ATF4 ELISA Kits) levels.

  6. stress pathways lead to the induction of the protein GADD34, which appears to provide protection against the toxic effects of the secreted virulence factors in Pseudomonas aeruginosa infection

  7. The data highlight independent interactions of PP1 (show PPA1 ELISA Kits) and eIF2alpha (show EIF2A ELISA Kits) with GADD34, demonstrating that GADD34 functions as a scaffold both in vitro and in cells

  8. GADD34 may play a neuroprotective role against amyloid-beta toxicity.

  9. GADD34 enhances autophagy and suppresses apoptosis stimulated by LPS (show IRF6 ELISA Kits) combined with amino acid deprivation through regulation of mTOR (show FRAP1 ELISA Kits) signaling pathway in macrophages.

  10. Data indicate that protein phosphatase 1 (show PPP1CB ELISA Kits) subunit GADD34 directly interacts with eukaryotic translation initiation factor 2 subunit alpha (eIF2alpha (show EIF2S1 ELISA Kits)).

Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A) Antigen Profile

Antigen Summary

This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation.

Alternative names and synonyms associated with Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A)

  • protein phosphatase 1, regulatory subunit 15A (PPP1R15A) Elisa Kit
  • protein phosphatase 1, regulatory (inhibitor) subunit 15A (PPP1R15A) Elisa Kit
  • protein phosphatase 1, regulatory (inhibitor) subunit 15A (Ppp1r15a) Elisa Kit
  • protein phosphatase 1, regulatory subunit 15A (Ppp1r15a) Elisa Kit
  • 9630030H21 Elisa Kit
  • GADD34 Elisa Kit
  • Myd116 Elisa Kit
  • Peg-3 Elisa Kit
  • RGD1624209 Elisa Kit

Protein level used designations for PPP1R15A

protein phosphatase 1, regulatory (inhibitor) subunit 15A , growth arrest and DNA damage-inducible protein GADD34 , growth arrest and DNA-damage-inducible 34 , myeloid differentiation primary response gene 116 , myeloid differentiation primary response protein MyD116 , protein phosphatase 1 regulatory subunit 15A , myeloid differentiation primary response protein MyD116 homolog , progression elevated gene 3 protein

GENE ID SPECIES
456191 Pan troglodytes
718350 Macaca mulatta
100449481 Pongo abelii
100591446 Nomascus leucogenys
17872 Mus musculus
23645 Homo sapiens
171071 Rattus norvegicus
514688 Bos taurus
476419 Canis lupus familiaris
Selected quality suppliers for Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A) ELISA Kits
Did you look for something else?