Browse our anti-XBP1 (XBP1) Antibodies

Full name:
anti-X-Box Binding Protein 1 Antibodies (XBP1)
On www.antibodies-online.com are 223 X-Box Binding Protein 1 (XBP1) Antibodies from 26 different suppliers available. Additionally we are shipping XBP1 Kits (35) and XBP1 Proteins (8) and many more products for this protein. A total of 282 XBP1 products are currently listed.
Synonyms:
cb918, D11Ertd39e, HTF, id:ibd1195, TREB-5, TREB5, trebf, wu:fb02h05, wu:fb63f10, XBP-1, xbp1, xbp1a, xbp1b, XBP1P1, XBP2, XBPP1, xXBP1

Most Popular Reactivities for anti-XBP1 (XBP1) Antibodies

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anti-Human XBP1 Antibodies:

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anti-Rat (Rattus) XBP1 Antibodies:

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Top referenced anti-XBP1 Antibodies

  1. Human Polyclonal XBP1 Primary Antibody for EIA, WB - ABIN955595 : Sudarshan, Schlegel, Liu: The HPV-16 E5 protein represses expression of stress pathway genes XBP-1 and COX-2 in genital keratinocytes. in Biochemical and biophysical research communications 2010 (PubMed)
    Show all 5 references for 955595

  2. Dog (Canine) Polyclonal XBP1 Primary Antibody for EIA, IHC (p) - ABIN374982 : Yokouchi, Hiramatsu, Hayakawa, Okamura, Du, Kasai, Takano, Shitamura, Shimada, Yao, Kitamura: Involvement of selective reactive oxygen species upstream of proapoptotic branches of unfolded protein response. in The Journal of biological chemistry 2008 (PubMed)

  3. Human Polyclonal XBP1 Primary Antibody for IF, WB - ABIN501132 : Yoshida, Matsui, Yamamoto, Okada, Mori: XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor. in Cell 2002 (PubMed)

  4. Cow (Bovine) Polyclonal XBP1 Primary Antibody for IHC, WB - ABIN2780640 : Davies, Barraclough, Stewart, Joyce, Eccles, Barraclough, Rudland, Sibson: Expression and splicing of the unfolded protein response gene XBP-1 are significantly associated with clinical outcome of endocrine-treated breast cancer. in International journal of cancer. Journal international du cancer 2008 (PubMed)

  5. Human Polyclonal XBP1 Primary Antibody for FACS, IHC (p) - ABIN651279 : Navon, Gatushkin, Zelcbuch, Shteingart, Farago, Hadar, Tirosh: Direct proteasome binding and subsequent degradation of unspliced XBP-1 prevent its intracellular aggregation. in FEBS letters 2009 (PubMed)

More Antibodies against XBP1 Interaction Partners

Human X-Box Binding Protein 1 (XBP1) interaction partners

  1. The findings indicate that IRE1 (show ERN1 Antibodies)-XBP1 downregulation distinguishes germinal center B-cell-like diffuse large B-cell lymphoma (DLBCL) from other DLBCL subtypes and contributes to tumor growth.

  2. XBP1 does not act as a direct activator of STAT3 phosphorylation. Hence, in regenerati (show DDR1 Antibodies)ng livers, XBP1 deficiency most likely affects STAT3 phosphorylation in an indirect manner, possibly related to unresolved ER stress.

  3. reciprocal regulation of Pin1 (show PIN1 Antibodies) and XBP1s is associated with the activation of oncogenic pathways, and the relationship of PIN1 (show PIN1 Antibodies) and XBP1 may be an attractive target for novel therapy in cancers

  4. Our data indicate that reduced response of IRE1alpha (show ERN1 Antibodies)/Xbp-1 signaling pathway to bortezomib may contribute to drug resistance in myeloma cells

  5. XBP1 regulates VEGF-mediated cardiac angiogenesis.

  6. XBP1s expression in mouse and human fibroblasts is critical for TiAl6 V4 particle-induced RANKL (show TNFSF11 Antibodies) expression and osteolysis

  7. The molecular-level exploration into the signaling mechanism was investigated for the respective role of the residues from the two important proteins from Homo sapiens ERalpha (show ESR1 Antibodies) and XBP-1 (bZIP domain)) for breast tumors metastasis via proliferation. It further dealt with the analysis and examination of the changes that are caused due to the point mutation K214R in the ERalpha (show ESR1 Antibodies) protein.

  8. plasma exposure resulted in expression of unfolded protein response (UPR) proteins such as glucoserelated protein 78 (GRP78 (show HSPA5 Antibodies)), protein kinase (show CDK7 Antibodies) R (PKR (show PKLR Antibodies))like ER kinase (PERK (show EIF2AK3 Antibodies)), and inositolrequiring enzyme 1 (IRE1 (show ERN1 Antibodies)). Elevated expression of spliced Xbox binding protein 1 (XBP1) and CCAAT/enhancerbinding protein homologous protein (CHOP (show DDIT3 Antibodies)) further confirmed that ROS (show ROS1 Antibodies) generatedby NTGP induces apoptosis through the ER stress

  9. Data suggest that XBP1 is a major component in endocrine pancreas that is crucial for glucose homeostasis and lipid metabolism; drugs targeting XBP1 signaling and endoplasmic reticulum stress/unfolded protein response in endocrine pancreas are potential approaches for treatment of disorders of glucose metabolism.

  10. High XBP1 expression is associated with glioma.

Mouse (Murine) X-Box Binding Protein 1 (XBP1) interaction partners

  1. The findings indicate that IRE1 (show ERN1 Antibodies)-XBP1 downregulation distinguishes germinal center B-cell-like diffuse large B-cell lymphoma (DLBCL) from other DLBCL subtypes and contributes to tumor growth.

  2. However, depletion of XBP1 and ATF6 (show ATF6 Antibodies), alone or in combination, prevented autophagy induction and significantly enhanced Japanese encephalitis virus-induced cell death.

  3. XBP1 expression regulates the unfolded protein response, acute-phase response, and DDR (show DDR1 Antibodies) in hepatocytes. In regenerating livers, XBP1 deficiency leads to endoplasmic reticulum stress and DNA damage.

  4. Ire1alpha (show ERN1 Antibodies)-Xbp1s and associated molecular targets link ER stress in arcuate Pomc (show POMC Antibodies) neurons to aspects of normal energy and glucose homeostasis.

  5. XBP1 regulates VEGF-mediated cardiac angiogenesis.

  6. Overexpression of active XBP1 partially reversed 4mu8C-induced anomalies in tight junctions.

  7. XBP1s expression in mouse and human fibroblasts is critical for TiAl6 V4 particle-induced RANKL (show TNFSF11 Antibodies) expression and osteolysis

  8. results reveal that XBP1s reduces hepatic lipogenic gene expression and improves hepatosteatosis in mouse models of obesity and insulin (show INS Antibodies) resistance, which leads us to conclude that XBP1s has anti-lipogenic properties in the liver.

  9. Study used three experimental approaches to enhance the IKKbeta (show IKBKB Antibodies) activity in the liver of obese mice and observed increased XBP1s activity, reduced endoplasmic reticulum stress, and a significant improvement in insulin (show INS Antibodies) sensitivity and consequently in glucose homeostasis.

  10. Findings indicate that PERK (show EIF2AK3 Antibodies) kinase-activating transcription factor 4 (ATF4 (show ATF4 Antibodies)) pathway affected the efficiency of X-box binding protein 1 (XBP1) mRNA splicing by regulating inositol-requiring enzyme 1alpha (IRE1alpha (show ERN1 Antibodies)) expression.

Pig (Porcine) X-Box Binding Protein 1 (XBP1) interaction partners

  1. analyzed XBP1 level and location to explore the effect of ER stress on oocyte maturation and developmental competency of porcine embryos in an in vitro culture system

  2. Knock-down of XBP1 enhanced endoplasmic reticulum stress-mediated cell death in porcine embryonic fibroblasts.

Cow (Bovine) X-Box Binding Protein 1 (XBP1) interaction partners

  1. Exposure of endothelial cells to VEGF (show VEGFA Antibodies), high glucose, or hydrogen peroxide up-regulated the XBP1/IRE1 alpha (show ERN1 Antibodies) and ATF6 (show ATF6 Antibodies) arms of the unfolded protein response compared with untreated cells.

Zebrafish X-Box Binding Protein 1 (XBP1) interaction partners

  1. Expression of xbp1 is significantly upregulated in the liver of Cdipt (show CDIPT Antibodies)-deficient zebrafish due to persistent endoplasmic reticulum stress. Cdipt (show CDIPT Antibodies)-deficient zebrafish exhibits hepatic lipid accumulation.

  2. zebrafish XBP-1 spliced form not only activates genes responsible for protein folding, transporting, glycosylation and Endoplasmic Reticulum associated degradation but also activates anti-apoptosis signal via IGF1 (show IGF1 Antibodies)/Akt (show AKT1 Antibodies) pathway in unfolded protein

Xenopus laevis X-Box Binding Protein 1 (XBP1) interaction partners

  1. XBP1 might function as an inhibitor of mesodermal and neural tissue formation by acting either as transcriptional activator or as repressor.

XBP1 Antigen Profile

Antigen Summary

This gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER), the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1). The resulting loss of 26 nt from the spliced mRNA causes a frame-shift and an isoform XBP1(S), which is the functionally active transcription factor. The isoform encoded by the unspliced mRNA, XBP1(U), is constitutively expressed, and thought to function as a negative feedback regulator of XBP1(S), which shuts off transcription of target genes during the recovery phase of ER stress. A pseudogene of XBP1 has been identified and localized to chromosome 5.

Alternative names and synonyms associated with XBP1

  • X-box binding protein 1 (xbp1) antibody
  • X-box binding protein 1 (XBP1) antibody
  • uncharacterized LOC100719734 (LOC100719734) antibody
  • X box-binding protein active isoform (LOC100037692) antibody
  • X-box binding protein 1 (Xbp1) antibody
  • cb918 antibody
  • D11Ertd39e antibody
  • HTF antibody
  • id:ibd1195 antibody
  • TREB-5 antibody
  • TREB5 antibody
  • trebf antibody
  • wu:fb02h05 antibody
  • wu:fb63f10 antibody
  • XBP-1 antibody
  • xbp1 antibody
  • xbp1a antibody
  • xbp1b antibody
  • XBP1P1 antibody
  • XBP2 antibody
  • XBPP1 antibody
  • xXBP1 antibody

Protein level used designations for XBP1

X-box binding protein 1 pseudogene 1 , X-box binding protein pseudogene 1 , X-box binding protein 1 , X-box-binding protein 1 , tax-responsive element-binding protein 5 , tax-responsive element-binding protein 5 homolog , XBP-1 , hepatocarcinogenesis-related transcription factor , X-box binding protein 1B

GENE ID SPECIES
407858 Xenopus (Silurana) tropicalis
458735 Pan troglodytes
654272 Takifugu rubripes
100719734 Cavia porcellus
100037692 Ovis aries
7494 Homo sapiens
22433 Mus musculus
100217386 Sus scrofa
541236 Bos taurus
289754 Rattus norvegicus
140614 Danio rerio
380215 Xenopus laevis
416918 Gallus gallus
477532 Canis lupus familiaris
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