Browse our anti-XBP1 (XBP1) Antibodies

Full name:
anti-X-Box Binding Protein 1 Antibodies (XBP1)
On www.antibodies-online.com are 223 X-Box Binding Protein 1 (XBP1) Antibodies from 27 different suppliers available. Additionally we are shipping XBP1 Kits (35) and XBP1 Proteins (8) and many more products for this protein. A total of 282 XBP1 products are currently listed.
Synonyms:
cb918, D11Ertd39e, HTF, id:ibd1195, TREB-5, TREB5, trebf, wu:fb02h05, wu:fb63f10, XBP-1, xbp1, xbp1a, xbp1b, XBP1P1, XBP2, XBPP1, xXBP1

Most Popular Reactivities for anti-XBP1 (XBP1) Antibodies

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anti-Human XBP1 Antibodies:

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Top referenced anti-XBP1 Antibodies

  1. Human Polyclonal XBP1 Primary Antibody for EIA, WB - ABIN955595 : Sudarshan, Schlegel, Liu: The HPV-16 E5 protein represses expression of stress pathway genes XBP-1 and COX-2 in genital keratinocytes. in Biochemical and biophysical research communications 2010 (PubMed)
    Show all 5 references for 955595

  2. Human Monoclonal XBP1 Primary Antibody for FACS - ABIN4899365 : Hasegawa, Wendling, He, Trilisky, Stevenson, Franey, Kinderman, Li, Piedmonte, Osslund, Shen, Ketchem: In vivo crystallization of human IgG in the endoplasmic reticulum of engineered Chinese hamster ovary (CHO) cells. in The Journal of biological chemistry 2011 (PubMed)

  3. Human Polyclonal XBP1 Primary Antibody for IF (p), IHC (p) - ABIN732728 : Li, Han, Shi: IRE1?-XBP1 Pathway Is Activated Upon Induction of Single-Prolonged Stress in Rat Neurons of the Medial Prefrontal Cortex. in Journal of molecular neuroscience : MN 2015 (PubMed)

  4. Human Polyclonal XBP1 Primary Antibody for ELISA, WB - ABIN263217 : Yokouchi, Hiramatsu, Hayakawa, Okamura, Du, Kasai, Takano, Shitamura, Shimada, Yao, Kitamura: Involvement of selective reactive oxygen species upstream of proapoptotic branches of unfolded protein response. in The Journal of biological chemistry 2008 (PubMed)

  5. Cow (Bovine) Polyclonal XBP1 Primary Antibody for WB - ABIN2777301 : Davies, Barraclough, Stewart, Joyce, Eccles, Barraclough, Rudland, Sibson: Expression and splicing of the unfolded protein response gene XBP-1 are significantly associated with clinical outcome of endocrine-treated breast cancer. in International journal of cancer. Journal international du cancer 2008 (PubMed)

  6. Human Polyclonal XBP1 Primary Antibody for FACS, IHC (p) - ABIN651279 : Navon, Gatushkin, Zelcbuch, Shteingart, Farago, Hadar, Tirosh: Direct proteasome binding and subsequent degradation of unspliced XBP-1 prevent its intracellular aggregation. in FEBS letters 2009 (PubMed)

More Antibodies against XBP1 Interaction Partners

Human X-Box Binding Protein 1 (XBP1) interaction partners

  1. IRE1alpha (show ERN1 Antibodies) was shown to cleave miR (show MLXIP Antibodies)-150 and thereby to release the suppressive effect that miR (show MLXIP Antibodies)-150 exerted on alphaSMA (show ACTA2 Antibodies) expression through c-Myb (show MYB Antibodies). Inhibition of IRE1alpha (show ERN1 Antibodies) was also demonstrated to block endoplasmic reticulum expansion through an XBP-1-dependent pathway.

  2. mTORC2 (show CRTC2 Antibodies) responds to glutamine (show GFPT1 Antibodies) catabolite levels to modulate the hexosamine biosynthesis enzyme GFAT1 (show GFPT1 Antibodies), and is essential for proper expression and nuclear accumulation of the GFAT1 (show GFPT1 Antibodies) transcriptional regulator, Xbp1s.

  3. we identify a positive feedback regulatory loop consisting of XBP1 and NCOA3 (show NCOA3 Antibodies) that maintains high levels of NCOA3 (show NCOA3 Antibodies) and XBP1 expression in breast cancer tissues.

  4. The findings indicate that IRE1 (show ERN1 Antibodies)-XBP1 downregulation distinguishes germinal center B-cell-like diffuse large B-cell lymphoma (DLBCL) from other DLBCL subtypes and contributes to tumor growth.

  5. XBP1 does not act as a direct activator of STAT3 phosphorylation. Hence, in regenerati (show DDR1 Antibodies)ng livers, XBP1 deficiency most likely affects STAT3 phosphorylation in an indirect manner, possibly related to unresolved ER stress.

  6. reciprocal regulation of Pin1 (show PIN1 Antibodies) and XBP1s is associated with the activation of oncogenic pathways, and the relationship of PIN1 (show PIN1 Antibodies) and XBP1 may be an attractive target for novel therapy in cancers

  7. Our data indicate that reduced response of IRE1alpha (show ERN1 Antibodies)/Xbp-1 signaling pathway to bortezomib may contribute to drug resistance in myeloma cells

  8. XBP1 regulates VEGF-mediated cardiac angiogenesis.

  9. XBP1s expression in mouse and human fibroblasts is critical for TiAl6 V4 particle-induced RANKL (show TNFSF11 Antibodies) expression and osteolysis

  10. The molecular-level exploration into the signaling mechanism was investigated for the respective role of the residues from the two important proteins from Homo sapiens ERalpha (show ESR1 Antibodies) and XBP-1 (bZIP domain)) for breast tumors metastasis via proliferation. It further dealt with the analysis and examination of the changes that are caused due to the point mutation K214R in the ERalpha (show ESR1 Antibodies) protein.

Mouse (Murine) X-Box Binding Protein 1 (XBP1) interaction partners

  1. mTORC2 (show CRTC2 Antibodies) responds to glutamine (show GFPT1 Antibodies) catabolite levels to modulate the hexosamine biosynthesis enzyme GFAT1 (show GFPT1 Antibodies), and is essential for proper expression and nuclear accumulation of the GFAT1 (show GFPT1 Antibodies) transcriptional regulator, Xbp1s.

  2. although feeding LS-Xbp1(-/-) mice cholesterol did not increase CYP7A1 (show CYP7A1 Antibodies) expression, serum C4 levels increased significantly up to levels similar to chow-fed Xbp1(fl/fl (show FLT3LG Antibodies)) mice and the total bile acid pool normalized. In conclusion, loss of hepatic XBP1 decreased the bile acid pool and CYP7A1 (show CYP7A1 Antibodies) synthetic activity.

  3. The findings indicate that IRE1 (show ERN1 Antibodies)-XBP1 downregulation distinguishes germinal center B-cell-like diffuse large B-cell lymphoma (DLBCL) from other DLBCL subtypes and contributes to tumor growth.

  4. However, depletion of XBP1 and ATF6 (show ATF6 Antibodies), alone or in combination, prevented autophagy induction and significantly enhanced Japanese encephalitis virus-induced cell death.

  5. XBP1 expression regulates the unfolded protein response, acute-phase response, and DDR (show DDR1 Antibodies) in hepatocytes. In regenerating livers, XBP1 deficiency leads to endoplasmic reticulum stress and DNA damage.

  6. Ire1alpha (show ERN1 Antibodies)-Xbp1s and associated molecular targets link ER stress in arcuate Pomc (show POMC Antibodies) neurons to aspects of normal energy and glucose homeostasis.

  7. XBP1 regulates VEGF-mediated cardiac angiogenesis.

  8. Overexpression of active XBP1 partially reversed 4mu8C-induced anomalies in tight junctions.

  9. XBP1s expression in mouse and human fibroblasts is critical for TiAl6 V4 particle-induced RANKL (show TNFSF11 Antibodies) expression and osteolysis

  10. results reveal that XBP1s reduces hepatic lipogenic gene expression and improves hepatosteatosis in mouse models of obesity and insulin (show INS Antibodies) resistance, which leads us to conclude that XBP1s has anti-lipogenic properties in the liver.

Pig (Porcine) X-Box Binding Protein 1 (XBP1) interaction partners

  1. analyzed XBP1 level and location to explore the effect of ER stress on oocyte maturation and developmental competency of porcine embryos in an in vitro culture system

  2. Knock-down of XBP1 enhanced endoplasmic reticulum stress-mediated cell death in porcine embryonic fibroblasts.

Cow (Bovine) X-Box Binding Protein 1 (XBP1) interaction partners

  1. Exposure of endothelial cells to VEGF (show VEGFA Antibodies), high glucose, or hydrogen peroxide up-regulated the XBP1/IRE1 alpha (show ERN1 Antibodies) and ATF6 (show ATF6 Antibodies) arms of the unfolded protein response compared with untreated cells.

Zebrafish X-Box Binding Protein 1 (XBP1) interaction partners

  1. Expression of xbp1 is significantly upregulated in the liver of Cdipt (show CDIPT Antibodies)-deficient zebrafish due to persistent endoplasmic reticulum stress. Cdipt (show CDIPT Antibodies)-deficient zebrafish exhibits hepatic lipid accumulation.

  2. zebrafish XBP-1 spliced form not only activates genes responsible for protein folding, transporting, glycosylation and Endoplasmic Reticulum associated degradation but also activates anti-apoptosis signal via IGF1 (show IGF1 Antibodies)/Akt (show AKT1 Antibodies) pathway in unfolded protein

Xenopus laevis X-Box Binding Protein 1 (XBP1) interaction partners

  1. XBP1 might function as an inhibitor of mesodermal and neural tissue formation by acting either as transcriptional activator or as repressor.

XBP1 Antigen Profile

Antigen Summary

This gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER), the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1). The resulting loss of 26 nt from the spliced mRNA causes a frame-shift and an isoform XBP1(S), which is the functionally active transcription factor. The isoform encoded by the unspliced mRNA, XBP1(U), is constitutively expressed, and thought to function as a negative feedback regulator of XBP1(S), which shuts off transcription of target genes during the recovery phase of ER stress. A pseudogene of XBP1 has been identified and localized to chromosome 5.

Alternative names and synonyms associated with XBP1

  • X-box binding protein 1 (xbp1) antibody
  • X-box binding protein 1 (XBP1) antibody
  • uncharacterized LOC100719734 (LOC100719734) antibody
  • X box-binding protein active isoform (LOC100037692) antibody
  • X-box binding protein 1 (Xbp1) antibody
  • cb918 antibody
  • D11Ertd39e antibody
  • HTF antibody
  • id:ibd1195 antibody
  • TREB-5 antibody
  • TREB5 antibody
  • trebf antibody
  • wu:fb02h05 antibody
  • wu:fb63f10 antibody
  • XBP-1 antibody
  • xbp1 antibody
  • xbp1a antibody
  • xbp1b antibody
  • XBP1P1 antibody
  • XBP2 antibody
  • XBPP1 antibody
  • xXBP1 antibody

Protein level used designations for XBP1

X-box binding protein 1 pseudogene 1 , X-box binding protein pseudogene 1 , X-box binding protein 1 , X-box-binding protein 1 , tax-responsive element-binding protein 5 , tax-responsive element-binding protein 5 homolog , XBP-1 , hepatocarcinogenesis-related transcription factor , X-box binding protein 1B

GENE ID SPECIES
407858 Xenopus (Silurana) tropicalis
458735 Pan troglodytes
654272 Takifugu rubripes
100719734 Cavia porcellus
100037692 Ovis aries
7494 Homo sapiens
22433 Mus musculus
100217386 Sus scrofa
541236 Bos taurus
289754 Rattus norvegicus
140614 Danio rerio
380215 Xenopus laevis
416918 Gallus gallus
477532 Canis lupus familiaris
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