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Browse our AGO2 (EIF2C2) ELISA Kits

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Eukaryotic Translation Initiation Factor 2C, 2 ELISA Kits (EIF2C2)
On are 6 Eukaryotic Translation Initiation Factor 2C, 2 (EIF2C2) ELISA Kits from 2 different suppliers available. Additionally we are shipping AGO2 Antibodies (67) and AGO2 Proteins (11) and many more products for this protein. A total of 87 AGO2 products are currently listed.
1110029L17Rik, 2310051F07Rik, AG02, ago, ago-2, AGO 2, ago2, AI225898, AL022874, Argonaute2, argonaute 2, AW546247, CG7439, CG13452, dAgo2, Dm Ago2, Dmel\\CG7439, eif2c1, eIF2C2, ENSMUSG00000072493, Gerp95, Gm10365, mKIAA4215, Q10, T19E23.7, T19E23_7
list all ELISA KIts Gene Name GeneID UniProt
EIF2C2 27161 Q9UKV8
EIF2C2 59117 Q9QZ81
EIF2C2 239528 Q8CJG0

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More ELISA Kits for AGO2 Interaction Partners

Arabidopsis thaliana Eukaryotic Translation Initiation Factor 2C, 2 (EIF2C2) interaction partners

  1. AGO1, AGO2 and AGO10 promoted anti-TuMV defense in a modular way in various organs, with AGO2 providing a prominent antiviral role in leaves. AGO5, AGO7 and AGO10 had minor effects in leaves.

  2. Base pairing at the 15th nucleotide of a miRNA duplex is important for miRNA sorting in both Arabidopsis AGO1 (show EIF2C1 ELISA Kits) and AGO2. AGO2 favours miRNA duplexes with no middle mismatches.

  3. Complementation analyses in ago mutant plants revealed that the catalytic residues of AGO1, AGO2, and AGO7 are required to restore the defects of Arabidopsis ago1-25, ago2-1, and zip-1 (AGO7-defective) mutants, respectively.

  4. AGO2 and HEN1 (show HENMT1 ELISA Kits) participate in the DCL2-mediated antiviral defense to ensure the survival of Turnip crinkle virus-infected plants at high temperature.

  5. This study reveals that miR408, which has a 5'A, regulates its target Plantacyanin through either AGO1 (show EIF2C1 ELISA Kits) or AGO2.

  6. AGO1 (show EIF2C1 ELISA Kits) and AGO2 are involved in defense against mutant of Cucumber mosaic virus, which act downstream the biogenesis of viral secondary siRNAs in a nonredundant and cooperative manner.

  7. Results show that AGO2-bound small RNA miR393b( *) targets a Golgi-localized SNARE (show NAPA ELISA Kits) gene, MEMB12.

  8. second layer is activated when the first layer is suppressed because AGO2 is repressed by AGO1 (show EIF2C1 ELISA Kits) via miR403

Human Eukaryotic Translation Initiation Factor 2C, 2 (EIF2C2) interaction partners

  1. overactivity of KRAS due to mutation inhibits localization of Ago2 to multivesicular endosomes (MVEs) and decreases Ago2 secretion in exosomes.

  2. TP53 (show TP53 ELISA Kits) regulates miRNA association with AGO2 to remodel the miRNA-mRNA interaction network

  3. These results support the notion that the cereblon (show CRBN ELISA Kits) binding partner AGO2 plays an important role in regulating MM cell growth and survival and AGO2 could be considered as a novel drug target for overcoming IMiD resistance in MM cells.

  4. KRAS engages AGO2 to enhance cellular neoplastic transformation.

  5. Authors found that target binding of core-RISC (show SCPEP1 ELISA Kits) starts at the seed region of the guide RNA. After target binding, four distinct reactions followed: target cleavage, transient binding, stable binding, and Argonaute 2 unloading.

  6. AGO2 suppression by miR (show MLXIP ELISA Kits)-132 affects the steady state levels of miR (show MLXIP ELISA Kits)-221 and miR (show MLXIP ELISA Kits)-146a, two miRNAs involved in angiogenesis and inflammation, respectively.

  7. DIS3L2 (show DIS3L2 ELISA Kits) interacts with Ago2 and governs target RNA-directed miRNA degradation.

  8. MiR (show MLXIP ELISA Kits)-138 suppresses hTERT expression in an AGO2-dependent manner.

  9. Knockdown of Ago2 in Huh7 cells and SMMC-7721 cells substantially decreased VEGF expression, whereas the restoration of AGO2 reversed both VEGF expression and secretion.

  10. genetic polymorphism in AGO2 may be a risk factor for the advanced lymph node metastasis of NPC (show NPC1 ELISA Kits) in Chinese populations, and AGO2 acts as an oncogene (show RAB1A ELISA Kits) in the development of NPC (show NPC1 ELISA Kits).

Mouse (Murine) Eukaryotic Translation Initiation Factor 2C, 2 (EIF2C2) interaction partners

  1. Increased AGO2 was detected in autophagy-deficient ATG5 (show ATG5 ELISA Kits)-/- and ATG16 (show ATG16L1 ELISA Kits)-/- mouse embryonic fibroblast cells. Chemical agents and VacA toxin, which disrupt autophagy, increased AGO2 expression in MEFs, epithelial cells lines, and human monocytes.

  2. DIS3L2 (show DIS3L2 ELISA Kits) interacts with Ago2 and governs target RNA-directed miRNA degradation.

  3. Results from the liver show that, siRNA targets 3'UTR (show UTS2R ELISA Kits) and the coding sequence (CDs (show ABHD5 ELISA Kits)) of endogenous genes in the presence Ago2 but in its absence, only 3'UTR (show UTS2R ELISA Kits)-targeted siRNA-mediated knockdown are active with the help of Ago1 (show EIF2C1 ELISA Kits) and Ago3 (show EIF2C3 ELISA Kits).

  4. Roquin (show RC3H1 ELISA Kits) also directly binds Argonaute2, a central component of the RNA-induced silencing complex, and miR (show MLXIP ELISA Kits)-146a, a microRNA that targets Icos (show ICOS ELISA Kits) mRNA.

  5. Target mRNAs induce tailing and trimming on Ago2-loaded miRNAs.

  6. Mouse AGO2 binds tighter to miRNA targets than its RNAi cleavage product, even though the cleaved product contains more base pairs. By re-writing the rules for nucleic acid hybridization, Argonautes allow oligonucleotides to serve as specificity determinants with thermodynamic and kinetic properties more typical of RNA-binding proteins than of RNA or DNA.

  7. Mouse Ago2 can be expressed as a fusion protein with the maltose binding protein in a soluble and enzymatically active form, without requiring coexpression with chaperones and cleave the complementary RNA in absence of other cellular factors.

  8. This study identifies the targeting of Ago2 by miR (show MLXIP ELISA Kits)-184 as an essential component of the compensatory response to regulate proliferation according to insulin (show INS ELISA Kits) sensitivity.

  9. study identifies Fkbp4 (show FKBP4 ELISA Kits) and Fkbp5 (show FKBP5 ELISA Kits) as novel components of the Ago2 RISC (show SCPEP1 ELISA Kits) loading complex

  10. Insights into the role of Ago2 in the systemic release of proteins from beta-cells.

Fruit Fly (Drosophila melanogaster) Eukaryotic Translation Initiation Factor 2C, 2 (EIF2C2) interaction partners

  1. We find there are large differences in evolutionary rates and gene turnover between pathways, and that paralogs of Ago2, Ago3, and Piwi/Aub show contrasting rates of evolution after duplication.

  2. Study shows that the Cricket Paralysis virus suppressor of RNA silencing, CrPV-1A but not B2 strongly interfere with the Ago-2-dependent miRNA silencing in Drosophila.

  3. siRNA biogenesis does not stabilize AGO2 in Drosophila.

  4. The results of this study found that mutations in Drosophila Argonaute 2 (Ago2) resulted in exacerbated transposon expression in the brain, progressive and age-dependent memory impairment, and shortened lifespan

  5. analysis of regulation of Argonaute (show EIF2C1 ELISA Kits) slicer activity by guide RNA 3' end interactions with the N-terminal lobe

  6. two new nuclear roles for Ago-2: one in pre-mRNA splicing and one in transcriptional repression.

  7. Highlighting its role in antiviral defense, fly Ago2 dissociates so slowly from extensively complementary target RNAs that essentially every fully paired target is cleaved. Conversely, mouse AGO2, which mainly mediates miRNA-directed repression, dissociates rapidly and with similar rates for fully paired and seed-matched targets.

  8. Nora virus VP1 and the viral suppressor of RNAi of Cricket paralysis virus (1A) antagonized Argonaute-2 (AGO2) Slicer activity of RNA induced silencing complexes pre-loaded with a methylated single-stranded guide strand.

  9. the key RNAi components Dicer (show DICER1 ELISA Kits) 2 (DCR2 (show TNFRSF10D ELISA Kits)) and Argonaute 2 (AGO2) associate with chromatin (with a strong preference for euchromatic, transcriptionally active, loci) and interact with the core transcription machinery

  10. Data show that AGO2 interacts physically with CTCF (show CTCF ELISA Kits) and CP190, and depletion of either CTCF (show CTCF ELISA Kits) or CP190 results in genome-wide loss of AGO2 chromatin association.

AGO2 (EIF2C2) Antigen Profile

Antigen Summary

This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in short-interfering-RNA-mediated gene silencing. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with AGO2 (EIF2C2)

  • eukaryotic translation initiation factor 2C, 2 (EIF2C2) Elisa Kit
  • Argonaute family protein (AGO2) Elisa Kit
  • argonaute RISC catalytic component 2 (AGO2) Elisa Kit
  • argonaute RISC catalytic component 2 (Ago2) Elisa Kit
  • argonaute RISC catalytic component 2 (ago2) Elisa Kit
  • argonaute RISC catalytic subunit 2 (Ago2) Elisa Kit
  • Argonaute 2 (AGO2) Elisa Kit
  • 1110029L17Rik Elisa Kit
  • 2310051F07Rik Elisa Kit
  • AG02 Elisa Kit
  • ago Elisa Kit
  • ago-2 Elisa Kit
  • AGO 2 Elisa Kit
  • ago2 Elisa Kit
  • AI225898 Elisa Kit
  • AL022874 Elisa Kit
  • Argonaute2 Elisa Kit
  • argonaute 2 Elisa Kit
  • AW546247 Elisa Kit
  • CG7439 Elisa Kit
  • CG13452 Elisa Kit
  • dAgo2 Elisa Kit
  • Dm Ago2 Elisa Kit
  • Dmel\\CG7439 Elisa Kit
  • eif2c1 Elisa Kit
  • eIF2C2 Elisa Kit
  • ENSMUSG00000072493 Elisa Kit
  • Gerp95 Elisa Kit
  • Gm10365 Elisa Kit
  • mKIAA4215 Elisa Kit
  • Q10 Elisa Kit
  • T19E23.7 Elisa Kit
  • T19E23_7 Elisa Kit

Protein level used designations for EIF2C2

eukaryotic translation initiation factor 2C, 2 , protein argonaute-2-like , PAZ Piwi domain protein , PPD , argonaute 2 , argonaute2 , eIF-2C 2 , eIF2C 2 , hAgo2 , protein argonaute-2 , protein slicer , GERp95 , golgi ER protein 95 kDa , Protein slicer , eukaryotic translation initiation factor 2C, 1 , Piwi/Argonaute family protein meIF2C2 , argonaute RISC catalytic component 2 , mAgo2 , eukaryotic translation initiation factor 2C 2 , Eukaryotic translation initiation factor 2C 2 , translation initiation factor eIF2C , AGO2-PB , AGO2-PC , AGO2-PE , ARGONAUTE2 , CG7439-PB , CG7439-PC , CG7439-PE , argonaute , argonaute-2

475107 Canis lupus familiaris
737376 Pan troglodytes
100082977 Ornithorhynchus anatinus
100464244 Ailuropoda melanoleuca
840016 Arabidopsis thaliana
27161 Homo sapiens
59117 Rattus norvegicus
446823 Xenopus laevis
239528 Mus musculus
404130 Bos taurus
100009457 Oryctolagus cuniculus
39683 Drosophila melanogaster
448205 Xenopus (Silurana) tropicalis
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