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Browse our FCER1A Proteins (FCER1A)

Full name:
Fc Fragment of IgE, High Affinity I, Receptor For, alpha Polypeptide Proteins (FCER1A)
On www.antibodies-online.com are 12 Fc Fragment of IgE, High Affinity I, Receptor For, alpha Polypeptide (FCER1A) Proteins from 7 different suppliers available. Additionally we are shipping FCER1A Antibodies (89) and FCER1A Kits (6) and many more products for this protein. A total of 117 FCER1A products are currently listed.
Synonyms:
Fce1a, fcepsilonri, FCER1A, FcERI, Fcr-5, Iger01, RATIGER01
list all proteins Gene Name GeneID UniProt
FCER1A 2205 P12319
FCER1A 25047 P12371
FCER1A 14125 P20489

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FCER1A Proteins (FCER1A) by Origin

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Top referenced FCER1A Proteins

  1. Human FCER1A Protein expressed in HEK-293 Cells - ABIN2181074 : Garman, Kinet, Jardetzky: Crystal structure of the human high-affinity IgE receptor. in Cell 1999 (PubMed)
    Show all 3 references for ABIN2181074

More Proteins for FCER1A Interaction Partners

Human Fc Fragment of IgE, High Affinity I, Receptor For, alpha Polypeptide (FCER1A) interaction partners

  1. F-AFE containing anti-allergic phytochemicals, including arctigenin, inhibited the activation of the FceRI receptor induced by the antigenIgE complex

  2. IgG2 and IgG3 are involved in recruiting CD32 (show FCGR2B Proteins) to inhibit activation of FcepsilonRI (show FCER1G Proteins) in human basophils.

  3. Asthmatics with reduced lung function had a higher frequency of Lin(-) CD34 (show CD34 Proteins)(hi) CD117(int/hi) Fc epsilon RI(+) blood mast cell progenitors than asthmatics with normal lung function.

  4. SNPs of FcepsilonR1alpha promoter region may be used as disease markers for IgE-mediated allergic inflammation caused by Dermatophagoides pteronyssinus.

  5. FcepsilonRI (show FCER1G Proteins) alpha-chain (show FCGRT Proteins) is an activating platelet endothelium aggregation receptor 1 (PEAR1 (show PEAR1 Proteins)) ligand.

  6. Tetraspanin CD151 (show CD151 Proteins) Is a Negative Regulator of FcepsilonRI (show FCER1G Proteins)-Mediated Mast Cell Activation

  7. FCER2 (show FCER2 Proteins) polymorphism rs3760687 affects moderately elevated total serum IgE levels, especially in the absence of homozygosity for the risk allele of FCER1A SNP rs2427837.

  8. Data indicate that antigen (Ag) targeting to FcepsilonRI (show FCER1G Proteins) inhibits the development of Ag-specific T cell immunity and induces T cell tolerance.

  9. FCER1A expressing dendritic cells and monocytes but not basophils, significantly contribute to serum hIgE clearance.

  10. Genetic polymorphism is associated with IgE levels in asthmatics in Germany

Mouse (Murine) Fc Fragment of IgE, High Affinity I, Receptor For, alpha Polypeptide (FCER1A) interaction partners

  1. Tim-3 (show HAVCR2 Proteins) acts at a receptor-proximal point to enhance Lyn (show LYN Proteins) kinase-dependent signaling pathways that modulate both immediate-phase degranulation and late-phase cytokine production downstream of FcepsilonRI ligation.

  2. Data indicate that white adipose tissue from IgE receptor FcR1-deficient Fcer1a(-/-) mice showed an increased expression of CCAAT-enhancer-binding protein-alpha (C-EBPalpha (show CEBPA Proteins)) and peroxisome proliferator-activated receptor-gamma (PPARgamma (show PPARG Proteins)).

  3. Conferring expression of FcepsilonRI to dendritic cells decreases the severity of food allergy and asthma in disease-relevant models suggesting anti-inflammatory IgE/FcepsilonRI signals.

  4. IgE-mediated activation of dendritic cells via IgE receptors binding in allergic Th2-type inflammation appears to be immune regulatory rather than pro-inflammatory. (Review)

  5. Tetraspanin CD151 (show CD151 Proteins) Is a Negative Regulator of FcepsilonRI-Mediated Mast Cell Activation

  6. IgE-mediated allergic hypersensitivity provokes release of renin (show REN Proteins) from both cultured and resident cardiac mast cells.

  7. CD72 (show CD72 Proteins) negatively regulates mouse mast cell functions and down-regulates the expression of KIT and FcepsilonRIalpha.

  8. Zinc-binding MT1 (show MT1 Proteins) and MT2 are key modulators of Fc epsilonRI-induced basophil production of IL-4 (show IL4 Proteins).

  9. Loss of Tespa1 in mouse mast cells led to hyper-responsiveness to stimulation via FcepsilonRI.

  10. Overexpression of miR (show MLXIP Proteins)-142-3p enhances FcepsilonRI-mediated degranulation.

FCER1A Protein Profile

Protein Summary

The immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. This receptor is comprised of an alpha subunit, a beta subunit, and two gamma subunits. The protein encoded by this gene represents the alpha subunit.

Alternative names and synonyms associated with FCER1A

  • Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide (FCER1A)
  • Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide (Fcer1a)
  • Fc receptor, IgE, high affinity I, alpha polypeptide (Fcer1a)
  • Fce1a protein
  • fcepsilonri protein
  • FCER1A protein
  • FcERI protein
  • Fcr-5 protein
  • Iger01 protein
  • RATIGER01 protein

Protein level used designations for FCER1A

Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide , high affinity immunoglobulin epsilon receptor subunit alpha , Fc IgE receptor, alpha polypeptide , Fc epsilon RI alpha-chain , Fc-epsilon RI-alpha , high affinity immunoglobulin epsilon receptor alpha-subunit , igE Fc receptor subunit alpha , immunoglobulin E receptor, high-affinity, of mast cells, alpha polypeptide , Fc receptor, IgE, high affinity I, alpha polypeptide , alpha polypeptide , fc-epsilon RI-alpha , fcERI

GENE ID SPECIES
469538 Pan troglodytes
478970 Canis lupus familiaris
506783 Bos taurus
719324 Macaca mulatta
100144427 Ovis aries
2205 Homo sapiens
25047 Rattus norvegicus
14125 Mus musculus
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