Browse our LCK (LCK) ELISA Kits

Full name:
Lymphocyte-Specific Protein tyrosine Kinase ELISA Kits (LCK)
On www.antibodies-online.com are 17 Lymphocyte-Specific Protein tyrosine Kinase (LCK) ELISA Kits from 5 different suppliers available. Additionally we are shipping LCK Antibodies (416) and LCK Proteins (15) and many more products for this protein. A total of 472 LCK products are currently listed.
Synonyms:
Hck-3, LCK, Lck1, Lcktkr, LSK, Lskt, p56, P56LCK, pp58lck, tkl, YT16, zgc:136695

More ELISA Kits for LCK Interaction Partners

Mouse (Murine) Lymphocyte-Specific Protein tyrosine Kinase (LCK) interaction partners

  1. We show a striking 65% reduction in cellularity, preferential development of gammadelta versus alphabeta T cells, and increased expression of IL-7R in the thymus of mice expressing Cre under the proximal lck promoter (lck-cre(+) mice)

  2. this work demonstrates a role for constitutive Lck activity in controlling antigen sensitivity

  3. this study defines distinct and complementary requirements for proximal and distal lck promoters during T-cell development

  4. Aurora A (show AURKA ELISA Kits) inhibition causes delocalized clustering of Lck at the immunological synapses and decreases its phosphorylation levels thus indicating Aurora A (show AURKA ELISA Kits) is required for maintaining Lck active during T-cell activation.

  5. essential for thymic development in presence or absence of Cbl, ensuring MHC restriction of T cells

  6. Lck-Dlx5 (show DLX5 ELISA Kits) mice develop T-ALLs that consistently acquire overexpression of Myc (show MYC ELISA Kits) and activation of Akt (show AKT1 ELISA Kits).

  7. Lck-CD8 (show CD8A ELISA Kits) interaction is required for initial CD8 (show CD8A ELISA Kits) recruitment.

  8. The kinase Itk (show ITK ELISA Kits) and the adaptor TSAd change the specificity of the kinase Lck in T cells by promoting the phosphorylation of Tyr192.

  9. CD4 (show CD4 ELISA Kits) is expressed in distinct nanoclusters and does not colocalize with T-cell receptor and active protein tyrosine kinase (show YES1 ELISA Kits) p56lck

  10. Study concludes that the intracellular state of Lck Study conclude that the intracellular state of Lck determines the specificity of thymic selection and that Lck association with coreceptor proteins during thymic selection is the mechanism by which MHC restriction is imposed on a randomly generated alphabetaTCR repertoire.

Human Lymphocyte-Specific Protein tyrosine Kinase (LCK) interaction partners

  1. data indicate that HSP65 (show HSPD1 ELISA Kits) suppresses cholesterol efflux and increases cellular cholesterol content through an Lck-mediated pathway in T cells

  2. LSKlow cells, which are derived from LSK cells in p18 (show CDKN2C ELISA Kits)(-/-) mice, possess lymphoid differentiation ability and short-term repopulation capability.

  3. These results suggest that PM lipids, including phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate, modulate interaction of Lck with its binding partners in the TCR signaling complex and its TCR signaling activities in a spatiotemporally specific manner via its SH2 domain.

  4. this study shows that p56(lck), which is essential for activation of T cells through the T-cell receptor, is also critical for signal transduction through Toll (show TLR4 ELISA Kits)-like receptors in T cells

  5. Aurora A (show AURKA ELISA Kits) inhibition causes delocalized clustering of Lck at the immunological synapses and decreases its phosphorylation levels thus indicating Aurora A (show AURKA ELISA Kits) is required for maintaining Lck active during T-cell activation.

  6. Results demonstrate that Lck represses oxidative phosphorylation through competitive binding with mitochondrial CRIF1 (show GADD45GIP1 ELISA Kits) in a kinase-independent manner.

  7. introducing bulky side-chains into this patch (GGxxG to GVxxL) impairs the Lck-independent role of CD4 in T cell activation upon TCR engagement of agonist and weak agonist stimulation.

  8. our results support a novel function of nuclear Lck in promoting human leukemic T cell survival through interaction with a tumor suppressor, CRIF1 (show GADD45GIP1 ELISA Kits)

  9. TSAD binds to and co-localizes with Nck (show NCK1 ELISA Kits). Expression of TSAD increases both Nck (show NCK1 ELISA Kits)-Lck and Nck (show NCK1 ELISA Kits)-SLP-76 (show LCP2 ELISA Kits) interaction in T cells.

  10. These findings demonstrate highly dynamic Lck palmitoylation kinetics that are essential for signaling downstream of the Fas receptor (show FAS ELISA Kits).

Pig (Porcine) Lymphocyte-Specific Protein tyrosine Kinase (LCK) interaction partners

  1. LCK gene could be an useful candidate gene in selection for increasing litter size in pigs.

LCK Antigen Profile

Antigen Summary

This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described.

Alternative names and synonyms associated with LCK

  • lymphocyte-specific protein tyrosine kinase (lck) Elisa Kit
  • lymphocyte-specific protein tyrosine kinase (LCK) Elisa Kit
  • lymphocyte-specific protein tyrosine kinase (LOC100349102) Elisa Kit
  • lymphocyte protein tyrosine kinase (Lck) Elisa Kit
  • lymphocyte-specific protein tyrosine kinase (Lck) Elisa Kit
  • Hck-3 Elisa Kit
  • LCK Elisa Kit
  • Lck1 Elisa Kit
  • Lcktkr Elisa Kit
  • LSK Elisa Kit
  • Lskt Elisa Kit
  • p56 Elisa Kit
  • P56LCK Elisa Kit
  • pp58lck Elisa Kit
  • tkl Elisa Kit
  • YT16 Elisa Kit
  • zgc:136695 Elisa Kit

Protein level used designations for LCK

lymphocyte protein tyrosine kinase , lymphocyte-specific protein tyrosine kinase , tyrosine-protein kinase Lck-like , leukocyte C-terminal Src kinase , lymphocyte cell-specific protein-tyrosine kinase , proto-oncogene tyrosine-protein kinase LCK , T-lymphocyte specific protein tyrosine kinase p56lck , p56(LSTRA) protein-tyrosine kinase , t cell-specific protein-tyrosine kinase , tyrosine-protein kinase Lck , tyrosine protein kinase , tyrosine-protein kinase LCK , p56-LCK

GENE ID SPECIES
414333 Danio rerio
456715 Pan troglodytes
100216439 Ovis aries
100349102 Oryctolagus cuniculus
100436326 Pongo abelii
100477981 Ailuropoda melanoleuca
16818 Mus musculus
3932 Homo sapiens
396460 Gallus gallus
313050 Rattus norvegicus
478151 Canis lupus familiaris
100233188 Sus scrofa
508890 Bos taurus
Selected quality suppliers for LCK (LCK) ELISA Kits
Did you look for something else?