Browse our Nuclear Receptor Subfamily 4, Group A, Member 3 Proteins (NR4A3)

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Nuclear Receptor Subfamily 4, Group A, Member 3 Proteins (NR4A3)
On www.antibodies-online.com are 15 Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3) Proteins from 7 different suppliers available. Additionally we are shipping Nuclear Receptor Subfamily 4, Group A, Member 3 Antibodies (218) and Nuclear Receptor Subfamily 4, Group A, Member 3 Kits (11) and many more products for this protein. A total of 256 Nuclear Receptor Subfamily 4, Group A, Member 3 products are currently listed.
Synonyms:
AI573420, CHN, CSMF, MINOR, MmTRA1a, MmTRA1b, NOR-1, NOR-2, Nor1, Nr4a3, PSCTK4, TEC, Tra1, Tra1a, Tra1b, Tras1, Tras2
list all proteins Gene Name GeneID UniProt
NR4A3 8013 Q92570
NR4A3 18124 Q9QZB6
NR4A3 58853 P51179

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Nuclear Receptor Subfamily 4, Group A, Member 3 Proteins (NR4A3) by Origin

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Top referenced Nuclear Receptor Subfamily 4, Group A, Member 3 Proteins

  1. Human NR4A3 Protein expressed in Wheat germ - ABIN1312985 : Medunjanin, Daniel, Weinert, Dutzmann, Burgbacher, Brecht, Bruemmer, Kähne, Naumann, Sedding, Zuschratter, Braun-Dullaeus: DNA-dependent protein kinase (DNA-PK) permits vascular smooth muscle cell proliferation through phosphorylation of the orphan nuclear receptor NOR1. in Cardiovascular research 2015 (PubMed)

More Proteins for Nuclear Receptor Subfamily 4, Group A, Member 3 Interaction Partners

Human Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3) interaction partners

  1. NR4A2 (show NR4A2 Proteins) and NR4A3 are components of a downstream transcriptional response to PKA activation in the neutrophil, and that they positively regulate neutrophil survival and homeostasis.

  2. NOR1 suppresses cancer stem-like cell properties in nasopharyngeal carcinoma cells by inhibiting the AKT (show AKT1 Proteins)-GSK-3beta-Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins)-ALDH1A1 (show ALDH1A1 Proteins) signaling circuit.

  3. Transcript analysis of four different aggressive lymphoma cell lines overexpressing either NR4A3 or NR4A1 (show NR4A1 Proteins) revealed that apoptosis was driven similarly by induction of BAK (show BAK1 Proteins), Puma (show BBC3 Proteins), BIK (show BIK Proteins), BIM (show BCL2L11 Proteins), BID (show BID Proteins), and Trail. Overall, our results showed that NR4A3 possesses robust tumor suppressor functions of similar impact to NR4A1 (show NR4A1 Proteins) in aggressive lymphomas

  4. Study found a marked down-regulated gene expression of the NR4A subfamily (NR4A1 (show NR4A1 Proteins), NR4A2 (show NR4A2 Proteins), and NR4A3) obtained from Parkinson's disease patients, but only a NR4A1 (show NR4A1 Proteins) decrease in Alzheimer's disease patients compared to healthy controls. This study reports that the entire NR4A subfamily and not only NR4A2 (show NR4A2 Proteins) could be systemically involved in Parkinson's disease.

  5. the role of intragenic DNA hypermethylation in reducing the expression of NR4A3 in AML (show RUNX1 Proteins)

  6. Overexpression of NR4A3 in adipocytes produces a complex phenotype characterized by impaired glucose metabolism and low serum catecholamines due to enhanced degradation by adipose tissue.

  7. NOR1 promotes the progression of hepatocellular carcinoma cells by activating Notch (show NOTCH1 Proteins) pathway.

  8. using RNA interference, the identified compounds corroborate the role of Tec kinase in unconventional secretion of FGF2 (show FGF2 Proteins).

  9. accumulation of NR4A3 is specific to alpha-synucleinopathy.

  10. miR-17 and -20a target NOR-1 thereby regulating NOR-1-dependent gene expression.

Zebrafish Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3) interaction partners

  1. NR4A2 (show NR4A2 Proteins) and NR4A3 are components of a downstream transcriptional response to PKA activation in the neutrophil, and that they positively regulate neutrophil survival and homeostasis.

Mouse (Murine) Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3) interaction partners

  1. these data indicate that in mature B cells, Tec and Btk may compete for activation of the Akt signaling pathway, whereby the activating capacity of Btk is limited by the presence of Tec kinase.

  2. NR4A3 plays an important role in the regulation of CD103 (show ITGAE Proteins)+ mDCs by regulating CCR7 (show CCR7 Proteins)-dependent cell migration.

  3. PLSCR1 (show PLSCR1 Proteins) aggravates anaphylactic reactions by increasing Fc epsion RI-dependent mast cell degranulation.

  4. Genetic knockdown of PLSCR1 (show PLSCR1 Proteins) activity reduces intracellular calcium dysregulation, prevents phosphatidylserine externalization, and enables months-long protection of vector-transduced, transgene-expressing cells from microglial phagocytosis.

  5. Study shows that NOR-1 can transduce survival signals in neuronal cells responsible for hypoxiainduced apoptotic insults through activation of a CREB (show CREB1 Proteins)/cIAP2 (show BIRC3 Proteins)-dependent mechanism

  6. Promoting Liver X receptor-alpha (show NR1H3 Proteins) expression inhibits lipopolysaccharide induced inflammation in Kupffer cells through elevating NOR-1 expression.

  7. Identified Nur77 (show NR4A1 Proteins)/Nor1 as novel regulators of thrombomodulin (show THBD Proteins) expression and function in vascular endothelial cells.

  8. Nr4a3 factor plays crucial role regulatory T cells, mediating the two defining characteristics of regulatory T cells: stability of cell lineage and immunosuppressive functions.

  9. Tec enhances c-Maf (show MAF Proteins)-dependent IL-4 (show IL4 Proteins) promoter activity. This effect of Tec is counteracted by Ptpn22 (show PTPN22 Proteins), which physically interacts with and facilitates tyrosine dephosphorylation of c-Maf (show MAF Proteins) thereby attenuating its transcriptional activity.

  10. Phospholipid scramblase 1 regulates phosphatidylserine exposure in response to oxygen stress, leading to beta2-glycoprotein I and IgM binding and lipid-mediated, inflammatory responses.

Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3) Protein Profile

Protein Summary

The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.

Alternative names and synonyms associated with Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3)

  • nuclear receptor subfamily 4, group A, member 3 (NR4A3)
  • neuron-derived orphan receptor-1 alfa (NOR-1)
  • nuclear receptor subfamily 4, group A, member 3 (nr4a3)
  • nuclear receptor subfamily 4, group A, member 3 (Nr4a3)
  • phospholipid scramblase 1 (Plscr1)
  • tec protein tyrosine kinase (TEC)
  • tec protein tyrosine kinase (Tec)
  • AI573420 protein
  • CHN protein
  • CSMF protein
  • MINOR protein
  • MmTRA1a protein
  • MmTRA1b protein
  • NOR-1 protein
  • NOR-2 protein
  • Nor1 protein
  • Nr4a3 protein
  • PSCTK4 protein
  • TEC protein
  • Tra1 protein
  • Tra1a protein
  • Tra1b protein
  • Tras1 protein
  • Tras2 protein

Protein level used designations for NR4A3

nuclear receptor subfamily 4, group A, member 3 , chondrosarcoma, extraskeletal myxoid, fused to EWS , mitogen-induced nuclear orphan receptor , neuron-derived orphan receptor 1 , nuclear hormone receptor NOR-1 , nuclear receptor subfamily 4 group A member 3 , translocated in extraskeletal chondrosarcoma , neural orphan nuclear receptor NOR1 , neural orphan receptor 1 , orphan nuclear receptor TEC , neuron-derived orphan receptor 1/2 , nuclear hormone receptor NOR-1/NOR-2 , PL scramblase 1 , ca(2+)-dependent phospholipid scramblase 1 , transplantability-associated protein 1 , tyrosine-protein kinase Tec , cytoplasmic tyrosine kinase, Dscr28C related

GENE ID SPECIES
464615 Pan troglodytes
397479 Sus scrofa
8013 Homo sapiens
548604 Danio rerio
420996 Gallus gallus
100684628 Canis lupus familiaris
528877 Bos taurus
18124 Mus musculus
58853 Rattus norvegicus
22038 Mus musculus
7006 Homo sapiens
21682 Mus musculus
84492 Rattus norvegicus
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