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Browse our Nuclear Receptor Subfamily 4, Group A, Member 3 Proteins (NR4A3)

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Nuclear Receptor Subfamily 4, Group A, Member 3 Proteins (NR4A3)
On www.antibodies-online.com are 11 Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3) Proteins from 5 different suppliers available. Additionally we are shipping Nuclear Receptor Subfamily 4, Group A, Member 3 Antibodies (193) and Nuclear Receptor Subfamily 4, Group A, Member 3 Kits (7) and many more products for this protein. A total of 222 Nuclear Receptor Subfamily 4, Group A, Member 3 products are currently listed.
Synonyms:
AI573420, CHN, CSMF, MINOR, MmTRA1a, MmTRA1b, NOR-1, NOR-2, Nor1, Nr4a3, PSCTK4, TEC, Tra1, Tra1a, Tra1b, Tras1, Tras2
list all proteins Gene Name GeneID UniProt
NR4A3 8013 Q92570
NR4A3 18124 Q9QZB6
NR4A3 58853 P51179

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Nuclear Receptor Subfamily 4, Group A, Member 3 Proteins (NR4A3) by Origin

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Top referenced Nuclear Receptor Subfamily 4, Group A, Member 3 Proteins

  1. Human NR4A3 Protein expressed in Wheat germ - ABIN1312985 : Medunjanin, Daniel, Weinert, Dutzmann, Burgbacher, Brecht, Bruemmer, Kähne, Naumann, Sedding, Zuschratter, Braun-Dullaeus: DNA-dependent protein kinase (DNA-PK) permits vascular smooth muscle cell proliferation through phosphorylation of the orphan nuclear receptor NOR1. in Cardiovascular research 2015 (PubMed)

More Proteins for Nuclear Receptor Subfamily 4, Group A, Member 3 Interaction Partners

Human Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3) interaction partners

  1. miR-17 and -20a target NOR-1 thereby regulating NOR-1-dependent gene expression.

  2. NR4A2 (show NR4A2 Proteins) is a key factor in multiple diseases, such as inflammation, cancer and cardiovascular diseases.

  3. Identified Nur77 (show NR4A1 Proteins)/Nor1 as novel regulators of thrombomodulin (show THBD Proteins) expression and function in vascular endothelial cells.

  4. Data identify NOR1 as a transcription factor induced during alternative differentiation of human macrophages and demonstrate that NOR1 modifies the alternative macrophage phenotype.

  5. A2M (show A2M Proteins) is expressed in the vasculature and NR4A receptors modulate VSMC MMP2 (show MMP2 Proteins)/9 activity by several mechanisms including the up-regulation of A2M (show A2M Proteins).

  6. In this review, a concise overview of the current understanding of the important metabolic roles governed by NR4A members NR4A1 (show NR4A1 Proteins), NR4A2 (show NR4A2 Proteins) and NR4A3 including their participation in a number of diseases shall be provided

  7. DNA-PK directly phosphorylates NOR-1, modulating vascular smooth muscle cell proliferation.

  8. NOR1 promotes the proliferation of pulmonary artery smooth muscle cells.

  9. Studies demonstrate that NOR1 deletion in hematopoietic stem cells accelerates atherosclerosis formation by promoting myelopoiesis in the stem cell compartment and by inducing local proatherogenic activities in the macrophage.

  10. Our data support a role for NOR-1 as a negative modulator of the acute response elicited by pro-inflammatory stimuli in the vasculature.

Mouse (Murine) Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3) interaction partners

  1. Promoting Liver X receptor-alpha (show NR1H3 Proteins) expression inhibits lipopolysaccharide induced inflammation in Kupffer cells through elevating NOR-1 expression.

  2. Identified Nur77 (show NR4A1 Proteins)/Nor1 as novel regulators of thrombomodulin (show THBD Proteins) expression and function in vascular endothelial cells.

  3. Nr4a3 factor plays crucial role regulatory T cells, mediating the two defining characteristics of regulatory T cells: stability of cell lineage and immunosuppressive functions.

  4. Tec enhances c-Maf (show MAF Proteins)-dependent IL-4 (show IL4 Proteins) promoter activity. This effect of Tec is counteracted by Ptpn22 (show PTPN22 Proteins), which physically interacts with and facilitates tyrosine dephosphorylation of c-Maf (show MAF Proteins) thereby attenuating its transcriptional activity.

  5. Phospholipid scramblase 1 regulates phosphatidylserine exposure in response to oxygen stress, leading to beta2-glycoprotein I and IgM binding and lipid-mediated, inflammatory responses.

  6. Studies demonstrate that NOR1 deletion in hematopoietic stem cells accelerates atherosclerosis formation by promoting myelopoiesis in the stem cell compartment and by inducing local proatherogenic activities in the macrophage.

  7. Our data support a role for NOR-1 as a negative modulator of the acute response elicited by pro-inflammatory stimuli in the vasculature.

  8. identify dectin-1 as the pathogen recognition receptor being required for Syk-dependent Tec activation.

  9. Btk (show BTK Proteins), Tec, Bmx (show BMX Proteins) are required for TLR-dependent signaling in many types of myeloid cells while being tissue-specific.

  10. Results indicate that DNA hypomethylation of the CpG island at Nr4a3 exon 3 is associated with low Nr4a3 expression, and correlates with poor prognosis of neuroblastoma (show ARHGEF16 Proteins).

Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3) Protein Profile

Protein Summary

The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.

Alternative names and synonyms associated with Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3)

  • nuclear receptor subfamily 4, group A, member 3 (NR4A3)
  • neuron-derived orphan receptor-1 alfa (NOR-1)
  • nuclear receptor subfamily 4, group A, member 3 (nr4a3)
  • nuclear receptor subfamily 4, group A, member 3 (Nr4a3)
  • phospholipid scramblase 1 (Plscr1)
  • tec protein tyrosine kinase (TEC)
  • tec protein tyrosine kinase (Tec)
  • AI573420 protein
  • CHN protein
  • CSMF protein
  • MINOR protein
  • MmTRA1a protein
  • MmTRA1b protein
  • NOR-1 protein
  • NOR-2 protein
  • Nor1 protein
  • Nr4a3 protein
  • PSCTK4 protein
  • TEC protein
  • Tra1 protein
  • Tra1a protein
  • Tra1b protein
  • Tras1 protein
  • Tras2 protein

Protein level used designations for NR4A3

nuclear receptor subfamily 4, group A, member 3 , chondrosarcoma, extraskeletal myxoid, fused to EWS , mitogen-induced nuclear orphan receptor , neuron-derived orphan receptor 1 , nuclear hormone receptor NOR-1 , nuclear receptor subfamily 4 group A member 3 , translocated in extraskeletal chondrosarcoma , neural orphan nuclear receptor NOR1 , neural orphan receptor 1 , orphan nuclear receptor TEC , neuron-derived orphan receptor 1/2 , nuclear hormone receptor NOR-1/NOR-2 , PL scramblase 1 , ca(2+)-dependent phospholipid scramblase 1 , transplantability-associated protein 1 , tyrosine-protein kinase Tec , cytoplasmic tyrosine kinase, Dscr28C related

GENE ID SPECIES
464615 Pan troglodytes
397479 Sus scrofa
8013 Homo sapiens
548604 Danio rerio
420996 Gallus gallus
100684628 Canis lupus familiaris
528877 Bos taurus
18124 Mus musculus
58853 Rattus norvegicus
22038 Mus musculus
7006 Homo sapiens
21682 Mus musculus
84492 Rattus norvegicus
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